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Study of stress inducing proteins in periodontitis.

Research Project

Project/Area Number 20592456
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionHiroshima University

Principal Investigator

SHIMAZU Atsushi  広島大学, 大学院・医歯薬学総合研究科, 助教 (10274094)

Co-Investigator(Kenkyū-buntansha) FUJIMOTO Katsumi  広島大学, 大学院・医歯薬学総合研究科, 助教 (40294566)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords歯周組織 / 歯周疾患 / ストレス / RAE-1
Research Abstract

The retinoic acid early inducible gene-1(RAE-1) is around 35 kDa protein induced by the exogenous stimulation, such as infection and tumorigenesis. However, there is completely unknown about the expression and the funcion of RAE-1 in periodontal tissue. In this study, we examined the the expression and the funcion of RAE-1 and our results provide novel evidence for a possible interaction in periodontal tissue and roles against the expgenous stumlation.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (16 results)

All 2011 2010 2009 2008

All Journal Article (5 results) (of which Peer Reviewed: 3 results) Presentation (11 results)

  • [Journal Article] Detection of a single bacterial cell using a 16S ribosomal RNA-specific oligonucleotide probe designed to investigate periodontal pathogens2009

    • Author(s)
      Tsuruda, K., Shimazu, A., Sugai, M.
    • Journal Title

      Oral Microbiol. Immunol.

      Volume: 24 Pages: 133-140

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detection of a single bacterial cell using a 16S ribosomal RNA-specific oligonucleotide probe designed to investigate periodontal pathogens2009

    • Author(s)
      Tsuruda, K., Shimazu, A., Sugai, M.
    • Journal Title

      Oral Microbiol.Immunol. 24

      Pages: 133-140

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of a single bacterial cell using a 16S ribosomal RNA-specific oligonucleotide probe designed to investigate periodontal pathogens.2009

    • Author(s)
      Tsuruda, K., Shimazu, A., Sugai, M.
    • Journal Title

      Oral Microbiol. Immunol. 24

      Pages: 133-140

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] NKレセプターリガンドによるIgA産生増強2008

    • Author(s)
      島津篤, 鶴田圭伊子
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 49(1) Pages: 22-27

    • Related Report
      2010 Final Research Report
  • [Journal Article] NKレセプターリガンドによるIgA産生増強2008

    • Author(s)
      島津 篤, 鶴田 圭伊子
    • Journal Title

      臨床免疫・アレルギー科 49

      Pages: 22-27

    • Related Report
      2008 Annual Research Report
  • [Presentation] エナメル芽細胞の増殖および分化に対するアメロブラスチンの生理活性2011

    • Author(s)
      廣瀬尚人, 島津篤, 谷本幸太郎, 丹根由起, 國松亮, 尾崎徳継, 吉見友希, 内田隆, 丹根一夫
    • Organizer
      第70回日本矯正歯科学術大会・第4回国際会議
    • Place of Presentation
      名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] マウス歯根形成期におけるアメロブラスチンの役割2010

    • Author(s)
      廣瀬尚人, 島津篤, 渡邊峰朗, 伊藤剛志, 村崎恭子, 高橋拡史, 谷本幸太郎, 内田隆, 丹根一夫
    • Organizer
      第69回日本矯正歯科学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-27
    • Related Report
      2010 Final Research Report
  • [Presentation] マウス歯根形成期におけるアメロブラスチンの役割2010

    • Author(s)
      廣瀬尚人, 他
    • Organizer
      第69回日本矯正歯科学会大会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2010-09-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 喫煙者における唾液中のストレス指標物質クロモグラニンAの定量2009

    • Author(s)
      久保皓太朗, 松本厚枝, 仁井谷善恵, 竹本俊伸, 島津篤, 鶴田佳伊子, 天野秀昭
    • Organizer
      第20回日本口腔衛生学会近畿・中国・四国地方会総会
    • Place of Presentation
      広島
    • Year and Date
      2009-06-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨芽細胞様細胞MC3T3-E1細胞におけるretinoic acid early inducible gene-Iの発現2008

    • Author(s)
      島津篤, 河原和子
    • Organizer
      第57回日本口腔衛生学会・総会
    • Place of Presentation
      さいたま
    • Year and Date
      2008-10-04
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨芽細胞様細胞MC3T3-E1細胞におけるretinoic acid early inducible gene-1の発現2008

    • Author(s)
      島津 篤
    • Organizer
      日本口腔衛生学会
    • Place of Presentation
      さいたま市
    • Year and Date
      2008-10-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 骨芽細胞におけるretinoic acid early inducible gene-1の発現について2008

    • Author(s)
      島津篤, 河原和子, 内田隆
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 硬組織形成過程におけるレチノイン酸誘導タンパク質retinoic acid early inducible gene-1(RAE-1)の機能解析2008

    • Author(s)
      島津篤
    • Organizer
      第1回口腔からQOL向上を目指す連携研究研究集会
    • Place of Presentation
      広島
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト歯周組織におけるストレス応答性タンパク質MICAの発現2008

    • Author(s)
      河原和子, 島津篤
    • Organizer
      第57回日本口腔衛生学会・総会
    • Place of Presentation
      さいたま
    • Related Report
      2010 Final Research Report
  • [Presentation] 歯周組織におけるストレス誘導タンパク質MICA遺伝子発現と調節因子2008

    • Author(s)
      河原和子, 島津篤, 加治屋幹人, 柴秀樹, 河口浩之
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト歯根膜細胞におけるMHC classI-related chain A(MICA)の発現2008

    • Author(s)
      河原和子, 島津篤, 加治屋幹人, 永原隆吉, 藤田剛, 柴秀樹
    • Organizer
      第51回春季日本歯周病学会学術大会
    • Place of Presentation
      さいたま
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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