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The relationship between calcification nano particle and dentalcariculus

Research Project

Project/Area Number 20592475
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionNational Institute of Public Health

Principal Investigator

TAMAKI Yoh  National Institute of Public Health, 政策科学部, 主任研究官 (50386827)

Co-Investigator(Kenkyū-buntansha) NOMURA Yoshiaki  鶴見大学, 歯学部・探索歯学講座, 准教授 (90350587)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords歯周病 / 歯石 / 異所性石灰化 / 石灰化ナノ粒子 / 歯石沈着
Research Abstract

We find out that the Calcificaton Nano Particle(CNPs) is existed both in human serum and saliva. The bovine serum protein separated by the high performance liquid chromatography were reacted to the monoclonal antibody for the CNPs. And these proteins were strongly attached to the hydroxyapatite. These results suggested that the CNPs may contribute to the dental calculus formation.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (46 results)

All 2011 2010 2009 2008 Other

All Journal Article (25 results) (of which Peer Reviewed: 13 results) Presentation (17 results) Book (2 results) Remarks (2 results)

  • [Journal Article] Effects of Coenzyme Q10 on Salivary Secretion.2011

    • Author(s)
      Ryo K, Ito A, Takatori R, Tai Y, Arikawa K, Seido T, Yamada T, Shinpo K, Tamaki Y, Fujii K, Yamamoto Y, Saito I
    • Journal Title

      Clinical Biochemistry. Clinical Biochemistry 44

      Pages: 669-674

    • Related Report
      2010 Final Research Report
  • [Journal Article] 地域住民を対象とした歯間ブラシの使用に重点をおいた歯周病予防のための健康教育プログラムの効果2011

    • Author(s)
      山崎洋治,湯之上志保,山口敏子,細久保和美,武儀山,武井,高田康二,中安美枝子,石川昭,中村宗達,玉置洋,野村義明,花田信弘
    • Journal Title

      口腔衛生学会誌 61(1)

      Pages: 13-21

    • NAID

      110008440557

    • Related Report
      2010 Final Research Report
  • [Journal Article] Effects of Coenzyme Q10 on Salivary Secretion.2011

    • Author(s)
      Ryo K, Ito A, Takatori R, Tai Y, Arikawa K, Seido T, Yamada T, Shinpo K, Tamaki Y, Fujii K, Yamamoto Y, Saito I.
    • Journal Title

      Clinical Biochemistry.

      Volume: 44 Pages: 669-674

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Therapeutic of Astaxanthin on Impairments in Salivary Secretion.2010

    • Author(s)
      Yamada T, Ryo K, Tai Y, Tamaki Y, Inoue H, Mishima K, Tsubota K, Saito I
    • Journal Title

      J.Clin.Biochem. 47

      Pages: 130-137

    • Related Report
      2010 Final Research Report
  • [Journal Article] HSPA1A is upregulated in periodontal ligament at early stage of tooth movement in rats.2010

    • Author(s)
      Arai C, Nomura Y, Ishikawa M, Noda K, Choi JW, Yashiro Y, Hanada N, Nakamura Y
    • Journal Title

      Histochem Cell Biol.(Epub 2010 Sep 1) 134(4)

      Pages: 337-43

    • Related Report
      2010 Final Research Report
  • [Journal Article] Evaluation of Therapeutic of Astaxanthin on Impairments in Salivary Secretion.2010

    • Author(s)
      Yamada T, Ryo K, Tai Y, Tamaki Y, Inoue H, Mishima K, Tsubota K, Saito I.
    • Journal Title

      J.Clin.Biochem.

      Volume: 47 Pages: 130-137

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HSPA1A is upregulated in periodontal ligament at early stage of tooth movement in rats.2010

    • Author(s)
      Arai C, Nomura Y, Ishikawa M, Noda K, Choi JW, Yashiro Y, Hanada N, Nakamura Y.
    • Journal Title

      Histochem Cell Biol.

      Volume: 134(4) Pages: 337-343

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 地域住民を対象とした歯間ブラシの使用に重点をおいた歯周病予防のための健康教育プログラムの効果2010

    • Author(s)
      山崎洋治, 湯之上志保, 山口敏子, 細久保和美, 武儀山, 武井, 高田康二, 中安美枝子, 石川昭, 中村宗達, 玉置洋, 野村義明, 花田信弘
    • Journal Title

      口腔衛生学会誌

      Volume: 61(1) Pages: 13-21

    • NAID

      110008440557

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Construction of a dental caries prediction model by data mining.2009

    • Author(s)
      Tamaki Y, Nomura Y, Katsumura S, Okada A, Yamada H, Tsuge S, Kadoma Y, Hanada N
    • Journal Title

      J Oral Sci. 51(1)

      Pages: 61-8

    • NAID

      130000666181

    • Related Report
      2010 Final Research Report
  • [Journal Article] Bonding durability against water of a fluorine-containing resin for precious metal alloys.2009

    • Author(s)
      Kadoma Y, Tamaki Y
    • Journal Title

      Dent Mater J. 28(5)

      Pages: 642-648

    • NAID

      10025916899

    • Related Report
      2010 Final Research Report
  • [Journal Article] Fluoride Intake from Tea in Japanese Infants.2009

    • Author(s)
      Kubota K, Kuroha K, Kawata K, Komiyama E, Tamaki Y, Uematsu M, Arakawa H
    • Journal Title

      Int J Oral Health. 5

      Pages: 7-15

    • Related Report
      2010 Final Research Report
  • [Journal Article] 中学生と高校生における歯の摩損に関する研究2009

    • Author(s)
      黒羽加寿美,久保田友嘉,荒川勇喜,川田和重,宋文群,戸田真司,川村和章,木本一成,玉置洋,荒川浩久
    • Journal Title

      口腔衛生学会雑誌 59(5)

      Pages: 577-585

    • NAID

      110008460539

    • Related Report
      2010 Final Research Report
  • [Journal Article] Asymmetry of the lips of orthognathic surgery patients.2009

    • Author(s)
      Yamashita Y, Nakamura Y, Shimada T, Nomura Y, Hirashita A
    • Journal Title

      Am J Orthod Dentofacial Orthop. 136(4)

      Pages: 559-63

    • Related Report
      2010 Final Research Report
  • [Journal Article] Morphological changes in the rat periodontal ligament and its vascularity after experimental tooth movement using superelastic forces.2009

    • Author(s)
      Noda K, Nakamura Y, Kogure K, Nomura Y
    • Journal Title

      Eur J Orthod.(Epub 2008 Dec 10) 31(1)

      Pages: 37-45

    • Related Report
      2010 Final Research Report
  • [Journal Article] Construction of a dental caries prediction model by data mining2009

    • Author(s)
      Tamaki Y, Nomura Y, Katsumura S, Okada A, Yamada H, Tsuge S, Kadoma Y, Hanada N.
    • Journal Title

      J Oral Sci 51

      Pages: 61-68

    • NAID

      130000666181

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bonding durability against water of a fluorine-containing resin for precious metal alloys2009

    • Author(s)
      Kadoma Y, Tamaki Y.
    • Journal Title

      Dent Mater J. 28(5)

      Pages: 642-648

    • NAID

      10025916899

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluoride Intake from Tea in Japanese Infants2009

    • Author(s)
      Kubota K, Kuroha K, Kawata K, Komiyama E, Tamaki Y, Uematsu M, Arakawa H.
    • Journal Title

      Int J Oral Health. 2009 5

      Pages: 7-15

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 中学生と高校生における歯の摩損に関する研究2009

    • Author(s)
      黒羽加寿美, 久保田友嘉, 荒川勇喜, 川田和重, 宋文群, 戸田真司, 川村和章, 木本一成, 玉置洋, 荒川浩久
    • Journal Title

      口腔衛生学会雑誌 59(5)

      Pages: 577-585

    • NAID

      110008460539

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 成人矯正治療患者の中切歯における鼓形空隙拡大の発生要因について2009

    • Author(s)
      香西陽子, 玉置洋, 野村義明, 戒田清和
    • Journal Title

      Orthodontic Waves-Japanese Edition 68(1)

      Pages: 9-15

    • NAID

      110007226050

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetry of the lips of orthognathic surgery patients2009

    • Author(s)
      Yamashita Y, Nakamura Y, Shimada T, Nomura Y, Hirashita A.
    • Journal Title

      Am J Orthod Dentofacial Orthop 136(4)

      Pages: 559-563

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Morphological changes in the rat periodontal ligament and its vascularity after experimental tooth movement using superelastic forces2009

    • Author(s)
      Noda K, Nakamura Y, Kogure K, Nomura Y.
    • Journal Title

      Eur J Orthod. 31(1)

      Pages: 37-45

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Community based screening for periodontitis using salivary test : Bulletein of Kanagawa Dental College2008

    • Author(s)
      Furuya M, Nomura Y, Tamaki Y, Sato T, Hanada N, Kamoi K, Arakawa H
    • Journal Title

      36(1)

      Pages: 3-9

    • Related Report
      2010 Final Research Report
  • [Journal Article] Factors affecting the oral condition of patients with severe motor and intellectual disabilities.2008

    • Author(s)
      IdairaY, Nomura Y, Tamaki Y, Katsumura S, Kodama S, Kurata K, AsadaY
    • Journal Title

      Oral Diseases. 14

      Pages: 435-9

    • Related Report
      2010 Final Research Report
  • [Journal Article] Factors affecting the oral condition of patients with severe motor and intellectual disabilities2008

    • Author(s)
      IdairaY, Nomura Y, Tamaki Y, Ktsumura S, Kodama S, Kurate K, et al.
    • Journal Title

      Oral Diseases 14

      Pages: 435-9

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of risk factor for dental caries from 6 to 8 years old children2008

    • Author(s)
      Katsumura S, Nishikawara F, Tamaki Y, Yamada H, Nakamura Y, Sato K, et al.
    • Journal Title

      Pediatric Dental Journal 18(1)

      Pages: 27-33

    • NAID

      10024180134

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 横須賀地区海上自衛隊員の喫煙状況と歯周疾患の関連性2011

    • Author(s)
      海老沢政人、玉置洋、有井丈朗、清水彰一郎
    • Organizer
      第56回防衛衛生学会(防衛衛生、第58巻別冊Vol.58.2011.P106)
    • Place of Presentation
      東京
    • Year and Date
      2011-02-03
    • Related Report
      2010 Final Research Report
  • [Presentation] 横須賀地区海上自衛隊員の喫煙状況と歯周疾患の関連性2011

    • Author(s)
      海老沢政人、玉置洋、有井丈朗、清水彰一郎
    • Organizer
      第56回防衛衛生学会 防衛衛生、第58巻別冊Vol.58.2011.P106
    • Place of Presentation
      東京
    • Year and Date
      2011-02-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 虚弱高齢者における摂食・嚥下機能と健康関連QOLとの関連性2010

    • Author(s)
      三浦宏子, 角保徳, 玉置洋, 安藤雄一, 江藤亜紀子, 井上一彦
    • Organizer
      第59回日本口腔衛生学会・口腔衛生学会雑誌 60(4) p386
    • Place of Presentation
      新潟
    • Year and Date
      2010-10-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 喫煙状況による歯周疾患リスクの解析2010

    • Author(s)
      海老沢政人、玉置洋、有井丈朗、大小田学、五味一博、新井高
    • Organizer
      第53回日本歯周病学会秋期学術大会(日本歯周病学会会誌52秋期特別号p99)
    • Place of Presentation
      高松
    • Year and Date
      2010-09-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 喫煙状況による歯周疾患リスクの解析2010

    • Author(s)
      海老沢政人、玉置洋、有井丈朗、大小田学、五味一博、新井高
    • Organizer
      第53回日本歯周病学会秋期学術大会
    • Place of Presentation
      高松
    • Year and Date
      2010-09-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地方衛生研究所の予算及び規模に関する現状について2010

    • Author(s)
      玉置洋、荻野大助、金谷泰宏、中西好子、小澤邦寿
    • Organizer
      第69回日本公衆衛生学会総会日本公衆衛生学会総会抄録集69回 p460
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 地方衛生研究所の食品検査に関する現状について2010

    • Author(s)
      荻野大助、玉置洋、金谷泰宏、中西好子、小澤邦寿
    • Organizer
      第69回日本公衆衛生学会総会日本公衆衛生学会総会抄録集69回 p461
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 臨地実習中におけるインシデント・アクシデントの実態と課題2009

    • Author(s)
      松江なるえ, 玉置洋, 種田憲一郎
    • Organizer
      第3回保健医療科学研究会
    • Place of Presentation
      埼玉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] ベイジアンネットワークを用いた齲蝕リスク評価の試み2009

    • Author(s)
      玉置洋、勝村聖子、柘植紳平、野村義明、花田信弘
    • Organizer
      第58回日本口腔衛生学会(口腔衛生学会雑誌59(4)p513)
    • Place of Presentation
      岐阜
    • Year and Date
      2009-10-11
    • Related Report
      2010 Final Research Report
  • [Presentation] ベイジアンネットワークを用いた齲蝕リスク評価の試み2009

    • Author(s)
      玉置洋, 勝村聖子, 柘植紳平, 野村義明, 花田信弘
    • Organizer
      第58回日本口腔衛生学会
    • Place of Presentation
      岐阜
    • Year and Date
      2009-10-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Improved screening for periodontal diseases using salivary biochemical markers and statistical modering.2009

    • Author(s)
      Nomura Y, Tamaki Y, A Eto, Ogino D, Nakamura Y, N Takahashi, F Hino, Koresawa K, Hanada N, Shimizu K
    • Organizer
      IADR PAPF/APR/JADR
    • Place of Presentation
      Wuhan China
    • Year and Date
      2009-10-03
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 歯科医療関連死を考える-診療関連死への歯科医師の対応-2009

    • Author(s)
      玉置洋
    • Organizer
      日本法歯科医学会 第3回学術大会
    • Place of Presentation
      歯科医師会館 東京
    • Year and Date
      2009-06-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] 唾液中のクロモグラニンAを指標としたストレス反応のパターン化2008

    • Author(s)
      篠原佐知緒、玉置洋、伊平弥生、栗山千裕、朝田芳信
    • Organizer
      第46回日本小児歯科学会大会(抄録集小児歯科学雑誌、46(2)p214)
    • Place of Presentation
      埼玉
    • Related Report
      2010 Final Research Report
  • [Presentation] 防衛省海上自衛隊における艦艇勤務者と陸上勤務者のう蝕罹患状況の比較2008

    • Author(s)
      田島聖士,海老沢政人,玉置洋,野村義明,花田信弘
    • Organizer
      第57回日本口腔衛生学会・総会(口腔衛生学会雑誌58(4)p350)
    • Place of Presentation
      埼玉
    • Related Report
      2010 Final Research Report
  • [Presentation] 学童期追跡調査における齲蝕リスクファクターの評価2008

    • Author(s)
      勝村聖子,玉置洋,野村義明,柘植紳平,花田信弘
    • Organizer
      第57回日本口腔衛生学会・総会(口腔衛生学会雑誌58(4)p445)
    • Place of Presentation
      埼玉
    • Related Report
      2010 Final Research Report
  • [Presentation] 唾液中のクロモグラニンAを指標としたストレス反応のパターン化2008

    • Author(s)
      篠原佐知緒, 玉置洋, 伊平弥生, 栗山千裕, 朝田芳信
    • Organizer
      第46回日本小児歯科学会大会
    • Place of Presentation
      埼玉
    • Related Report
      2008 Annual Research Report
  • [Presentation] 鶴見大学歯学部附属病院における外来来院患者に対する満足度調査2008

    • Author(s)
      玉置洋, 今中正浩, 佐藤慶太, 新井高
    • Organizer
      第10回医療マネジメント学会学術総会
    • Place of Presentation
      名古屋
    • Related Report
      2008 Annual Research Report
  • [Book] 歯科衛生士テキスト 口腔衛生学-口腔保健統計を含む-2008

    • Author(s)
      荒川浩久, 尾崎哲則, 神原正樹, 向井美恵, 玉置洋, 他
    • Total Pages
      12
    • Publisher
      学建書院
    • Related Report
      2008 Annual Research Report
  • [Book] 歯科医師・歯科衛生士のための唾液検査ハンドブック2008

    • Author(s)
      鴨井久一, 花田信弘, 佐藤慶太, 玉置洋, 他
    • Total Pages
      6
    • Publisher
      ヒョーロン・パブリッシャーズ
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.niph.go.jp/soshiki/seisaku/index.html

    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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