Liposome-Encapsulated Hemoglobin Alleviates Hearing Loss After Transient Cochlear Ischemia

• Project/Area Number: 20599011
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: Ehime University
• Principal Investigator: OKADA Masahiro Ehime University, 医学部附属病院, 医員 (20512130)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,390,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥390,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥1,700,000 (Direct Cost: ¥1,700,000)
• Keywords: 人工酸素運搬体 / 内耳一過性虚血 / 聴性脳幹反応 / 蝸牛有毛細胞 / 一過性内耳虚血

Research Abstract

Pre-treatment or post-treatment with liposome-encapsulated hemoglobin, which is one of artificial red blood cells, was protective in mitigating hearing loss and underlying pathological damage.

Research Products

• [Journal Article] 突発性難聴の臨床的検討-予後因子について (2011)
  • Author(s): 岡田昌浩、中村光士郎、暁清文
  • Journal Title: 愛媛医学 30巻 Pages: 16-21
  • Peer Reviewed
• [Journal Article] 突発性難聴の臨床的検討-予後因子について (2011)
  • Author(s): 岡田昌浩
  • Journal Title: 愛媛医学 Volume: 30 Pages: 16-21
  • Peer Reviewed
• [Presentation] Liposome-encapsulated hemoglobin alleviates hearing loss after transient cochlear ischemia and reperfusion (2010)
  • Author(s): 岡田昌浩
  • Place of Presentation: プラハ、チェコ
  • Year and Date: 2010-09-01
• [Presentation] Liposome-encapsulated hemoglobin alleviates hearing loss after transient cochlear ischemia and reperfusion (2010)
  • Author(s): Okada Masahiro
  • Organizer: 47^<th> Inner ear biology workshop
  • Place of Presentation: プラハ、チェコ
  • Year and Date: 2010-09-01
• [Presentation] 内耳虚血・再灌流障害に対する人工酸素運搬体の有用性の検討 (2010)
  • Author(s): 岡田昌浩
  • Organizer: 日本耳鼻咽喉科学会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-05-20
• [Presentation] 内耳虚血・再灌流障害に対する人工酸素運搬体の有用性の検討 (2010)
  • Author(s): 岡田昌浩
  • Organizer: 日本耳鼻咽喉科学会総会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-05-20