| Budget Amount *help |
¥4,060,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥660,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Research Abstract |
The NALP3 and IPAF proteins are known to induce inflammation. In this study, I attempted to identify the factors that directly activate NALP3 and IPAF. Although I could not isolate such factors during this period, I revealed many important features in the chemical process of the NALP3 activation. On the basis of these findings, I will continue searching the NALP3- and IPAF-ligands.
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