| Project/Area Number |
20602018
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
疼痛学
|
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
YUHI Tomoaki University of Occupational and Environmental Health, Japan, 医学部, 助教 (60330982)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
FUETA Yukiko 産業医科大学, 産業保健学部, 講師 (10132482)
UENO Susumu 産業医科大学, 産業生態科学研究所, 教授 (00279324)
|
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 神経因性疼痛 / 磁気刺激 / 反復経頭蓋磁気刺激 / von Freyフィラメント / rTMS / Plantar試験 / 反復経頭蓋磁気刺激法 / Elマウス / 機械的非侵害刺激 |
|---|
| Research Abstract |
In this research project, we tried to clarify whether rTMS can modulate the neuropathic pain in the mouse neuropathic pain model. As a result, we found that low-frequency rTMS reduces the excitability of frontal cingulate gyrus of mouse and decreases the neuropathic pain. Our results suggest rTMS has the potency to treat the neuropathic pain.
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