Chemical-biological Study on the Bioactive Compounds from Marine Algae
Project/Area Number |
20611012
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Chemical biology
|
Research Institution | Hiroshima University |
Principal Investigator |
|
Project Period (FY) |
2008 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 赤潮プランクトン / 渦鞭毛藻 / ヘテロカプサ・サーキュラリスカーマ / 構造決定トレーサー分子 / 有機触媒 / 二枚貝致死活性物質 / 構造活性相関 / 構造決定 / トレーサー分子 / 有機分子触媒 |
Research Abstract |
In order to elucidate the chemical structures of the toxic substances and the biological activities of the harmful phytoplankton, Heterocapsa circularisquama caused mass mortalities of bivalves, e. g. oyster, the spectroscopic analyses of toxic compounds and the chemical degradation reactions were carried out. Also, in order to construct the the partial structure of the toxic compounds, the novel organocatalyst which catalyzed for the enantioselective aldol and Michael reactions and the desymmetrization of symmetric alcohols were developed.
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Report
(6 results)
Research Products
(65 results)