| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
To elucidate mechanisms underlying biological responses of heavy-ion irradiated cells, a targeting method of subcellular regions using focusing heavy-ion microbeam was developed. An installation of a cell targeting system, an establishment of protocol for preparing target sample, and a development of an image analysis code that can extract cell coordinates from fluorescent-dye-stained cell image were carried out. The developed system was able to target and irradiate individual cultured cells using focusing heavy-ion microbeam.
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