Synthesis of Coordinatively Unsaturated Iron Complexes and C-H Bond Activation
| Project/Area Number |
20613004
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Element strategy
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| Research Institution | Nagoya University |
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Principal Investigator |
OHKI Yasuhiro Nagoya University, 大学院・理学研究科, 准教授 (10324394)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 鉄 / C-H結合活性化 / 配位不飽和 / 有機金属 / 触媒 / 有機金属錯体 / N-ヘテロ環カルベン |
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| Research Abstract |
The activation of C-H bonds is a key elementary step of organometallic reactions, and has great utility in organic synthesis. As a requirement for successful C-H bond activation under mild conditions would be preparation of coordinatively unsaturated complexes, we have synthesized coordinatively unsaturated half-sandwich iron complexes of N-heterocyclic carbenes. The sequential C-H bond activation and borylation reactions were found to occur upon treatment of the iron complexes with thiophene, furan, benzothiophene, benzofuran, or pyridine, followed by addition of hydroboranes. Based on these findings on stoichiometric reactions, we have developed the catalytic C-H bond activation/borylation of furans and thiophenes mediated by a half-sandwich iron complex of the methyl-substituted N-heterocyclic carbene. We have also conducted a series of reactions of the new iron complexes with nearly stoichiometric amount of substrate, to gain mechanistic insights.
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Report
(4 results)
Research Products
(71 results)
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[Journal Article] Exploring the Limits of Frustrated Lewis Pair Chemistry with Alkynes : Detection of a System that Favors 1,1-Carboboration over Cooperative 1,2-P/B-Addition2010
Author(s)
Chao Chen, Florian Eweiner, Birgit Wibbeling, Roland Frohlich, Shunsuke Senda, Yasuhiro Ohki, Kazuyuki Tatsumi, Stefan Grimme, Gerald Kehr, Gerhard Erker.
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Journal Title
Chem.Asian J 5
Pages: 2199-2208
Related Report
Peer Reviewed
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[Journal Article] Exploring the Limits of Frustrated Lewis Pair Chemistry with Alkynes : Detection of a System that Favors 1,1-Carboboration over Cooperative 1,2-P/B-Addition2010
Author(s)
Chen, C. ; Eweiner, F. ; Wibbeling, B. ; Frchlich, R. ; Senda, S. ; Ohki, Y. ; Tatsumi, K. ; Grimme, S. ; Kehr, G. ; Erker, G.
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Journal Title
Chem. Asian J.
Volume: 5
Pages: 2199-2208
Related Report
Peer Reviewed
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[Journal Article] Evidence for a Rapid Degenerate Hetero-Cope-type Rearrangement in Cp*W(S)_2S-CH_2-CH=CH_22009
Author(s)
Florian Eweiner, Shunsuke Senda, Klaus Bergander, Christian Muck-Lichtenfeld, Stefan Grimme, Roland Frolich, Michiko Aoyama, Hiroyuki Kawaguchi, Yasuhiro Ohki, Tsuyoshi Matsumoto, Gerald Kehr, Kazuyuki Tatsumi, Gerhard Erker
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Journal Title
Chem.Asian J. 4
Pages: 1830-1833
Related Report
Peer Reviewed
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[Journal Article] Synthesis, Structures, and Electronic Properties of [8Fe-7S] Cluster Complexes Modeling the Nitrogenase P-cluster2009
Author(s)
Yasuhiro Ohki, Motosuke Imada, Yusuke Sunada, Ayuro Murata, Shun Ohta, Masaru Honda, Takahiro Sasamori, Norihiro Tokitoh, Motomi Katada, Kazuyuki Tatsumi
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Journal Title
J.Am.Chem.Soc. 131
Pages: 13168-13178
Related Report
Peer Reviewed
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[Journal Article] Evidence for a Rapid Degenerate Hetero-Cope-type Rearrangement in Cp*W(S)_2S-CH_2-CH=CH_22009
Author(s)
Florian Eweiner, Shunsuke Senda, Klaus Bergander, Christian Muck-Lichtenfeld, Stefan Grimme, Roland Frolich, Michiko Aoyama, Hiroyuki Kawaguchi, Yasuhiro Ohki, Tsuyoshi Matsumoto, Gerald Kehr, Kazuyuki Tatsumi, Gerhard Erker
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Journal Title
Chem. Asian J. 4
Pages: 1830-1833
Related Report
Peer Reviewed
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[Journal Article] Synthesis, Structures, and Electronic Properties of[8Fe-7S]Cluster Complexes Modeling the Nitrogenase P-cluster2009
Author(s)
Yasuhiro Ohki, Motosuke Imada, Yusuke Sunada, Ayuro Murata, Shun Ohta, Masaru Honda, Takahiro Sasamori, Norihiro Tokitoh, Motomi Katada, Kazuyuki Tatsumi
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Journal Title
J. Am. Chem. Soc. 131
Pages: 13168-13178
Related Report
Peer Reviewed
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