Neural processes underlying motor control and learning of bimanual movement

• Project/Area Number: 20670008
• Research Category: Grant-in-Aid for Young Scientists (S)
• Allocation Type: Single-year Grants
• Research Field: Physical education
• Research Institution: The University of Tokyo
• Principal Investigator: NOZAKI Daichi The University of Tokyo, 教育学研究科(研究院), 准教授 (70360683)
• Project Period (FY): 2008 – 2012
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥76,700,000 (Direct Cost: ¥59,000,000、Indirect Cost: ¥17,700,000); Fiscal Year 2011: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000); Fiscal Year 2010: ¥22,750,000 (Direct Cost: ¥17,500,000、Indirect Cost: ¥5,250,000); Fiscal Year 2009: ¥12,480,000 (Direct Cost: ¥9,600,000、Indirect Cost: ¥2,880,000); Fiscal Year 2008: ¥31,200,000 (Direct Cost: ¥24,000,000、Indirect Cost: ¥7,200,000)
• Keywords: 身体システム学 / 運動学習 / 運動制御 / リーチング運動 / 心理物理

Research Abstract

ヒトは複数身体部位の運動を組み合わせて、多様な複合運動を構成する能力を備えている。我々はこれまでの片腕・両腕運動を対象とした研究により「素過程(各腕を動かす脳内過程)が組み合わされて、複合運動(両腕運動)が構成される」という、両腕運動研究が拠り所としていた常識的な概念が誤りであることを明らかにしてきた。この「両腕運動を構成する右腕(左腕)運動は、片腕運動としての右腕(左腕)運動とは異なっている」という新しい描像を研究の出発点として設定すると、両腕運動制御の問題は単なる「協調」の問題だけに留まらず、その一見非効率な構造の機能的意義、構造の脳内表象、構造が運動学習過程に及ぼす影響、など多様かつ本質的に重要な問題を含んでいることが分かる。ロボットアームを用いた心理物理的実験、脳機能イメージング、片麻痺患者の調査、数学的モデル構築などの方法を用いて、これらの問題を解決し、両腕運動が構成・制御される原理解明を目指す。

Research Products

• [Journal Article] Asymmetric transfer of visuomotor learning between discrete and rhythmic movements. (2010)
  • Author(s): Ikegami T, Hirashima M, Taga G, Nozaki D.
  • Journal Title: Journal of Neuroscience 30 Pages: 4515-4521
• [Journal Article] The "cutaneous rabbit"hopping out of the body. (2010)
  • Author(s): Miyazaki M, Hirashima M, Nozaki D.
  • Journal Title: Journal of Neuroscience 30 Pages: 1856-1860
  • NAID: 120005246266
• [Journal Article] How does stochastic resonance work within the human brain?-psychophysics of internal and external noise. (2010)
  • Author(s): Aihara T, Kitajo K, Nozaki D, Yamamoto Y
  • Journal Title: Chemical Physics Volume: 375 Pages: 616-624
  • Peer Reviewed
• [Journal Article] Temporal correlations in center of body mass fluctuation during standing and walking. (2010)
  • Author(s): Abe MO, Masani K, Nozaki D, AkaiM, Nakazawa K
  • Journal Title: Human Movement Science Volume: 29 Pages: 556-566
  • Peer Reviewed
• [Journal Article] Asymmetric transfer of visuomotor learning between discrete and rhythmic movements (2010)
  • Author(s): Tsuyoshi Ikegami, Masaya Hirashima, Gentaro Taga, Daichi Nozaki
  • Journal Title: Journal of Neuroscience 30(12) Pages: 4515-4521
  • Peer Reviewed
• [Journal Article] The "cutaneous rabbit" hopping out of the body. (2010)
  • Author(s): Miyazaki M, Hirashima M, Nozaki D
  • Journal Title: Journal of Neuroscience 30 Pages: 1856-1860
  • NAID: 120005246266
  • Peer Reviewed
• [Journal Article] Temporal correlations in center of body mass fluctuation during standing and walking. (2010)
  • Author(s): Abe MO, Masani K, Nozaki D, Akai M, Nakazawa K
  • Journal Title: Human Movement Science (印刷中)
  • Peer Reviewed
• [Journal Article] A Generalized method to estimate waveforms common across trials from EEGs. (2010)
  • Author(s): Takeda Y, Sato M, Yamanaka K, Nozaki D, Yamamoto Y
  • Journal Title: Neuroimage 51 Pages: 629-641
  • Peer Reviewed
• [Journal Article] Torque interaction among adjacent joints due to the action of bi-articular muscles. (2009)
  • Author(s): Nozaki D
  • Journal Title: Medicine & Science in Sports & Exercise 41 Pages: 205-209
• [Journal Article] Multi-compartment model can explain partial transfer of learning within the same limb between unimanual and bimanual reaching. (2009)
  • Author(s): Nozaki D, Scott SH
  • Journal Title: Experimental Brain Research 194 Pages: 451-453
• [Journal Article] Shaping appropriate locomotive motor output through interlimb neural pathway within spinal cord in humans. (2008)
  • Author(s): Kawashima N, Nozaki D, Abe MO, Nakazawa K
  • Journal Title: Journal of Neurophysiology 99 Pages: 2946-2955
• [Journal Article] Shaping appropriate locomotive motor output through interlimb neural pathway within spinal cord in humans (2008)
  • Author(s): Kawashima N, Nozaki D, Abe M, Nakazawa K
  • Journal Title: Journal of Neurophysiology 99 Pages: 2946-2955
  • Peer Reviewed
• [Presentation] Distinct motor plans enable simultaneous adaptation to conflicting force fields (2011)
  • Author(s): Hirashima M, Nozaki D
  • Organizer: Inaugural International Academy of Sportology
  • Place of Presentation: Juntendo University (Tokyo)
  • Year and Date: 2011-03-05
• [Presentation] Flexible switching of multiple internal models during bimanual movement (2011)
  • Author(s): Yokoi A, Hirashima M, Nozaki O
  • Organizer: Inaugural International Academy of Sportology
  • Place of Presentation: Juntendo University (Tokyo)
  • Year and Date: 2011-03-05
• [Presentation] 柔軟な両腕協調運動を実現する運動学習メカニズム (2011)
  • Author(s): 野崎大地
  • Organizer: 日本神経回路学会「脳と心のメカニズム」第11回冬のワークショップ
  • Place of Presentation: 留寿都
• [Presentation] Context dependent formation of internal models for reaching movements. (2011)
  • Author(s): Nozaki D.
  • Organizer: Conference on Systems Neuroscience and Rehabilitation 2011
  • Place of Presentation: Tokorozawa
• [Presentation] 柔軟な両腕協調運動を実現する運動学習メカニズム (2011)
  • Author(s): 野崎大地
  • Organizer: 日本神経回路学会「脳と心のメカニズム」第11回夏のワークショップ
  • Place of Presentation: ルスツリゾート(北海道)
• [Presentation] Dancing Baby -How do 3- to 4-month-old infants respond to a musical beat? (2011)
  • Author(s): Fujii S, Watanabe H, Hirashima M, Nozaki D
  • Organizer: International Workshop for Young Researchers "Knowing self, knowing others"
  • Place of Presentation: 京都大学(京都府)
• [Presentation] Context dependent formation of internal models for reaching movements (2011)
  • Author(s): Nozaki D
  • Organizer: Conference on Systems Neuroscience and Rehabilitation
  • Place of Presentation: College of NRCD (Saitama)
• [Presentation] Adaptation to a novel dynamical environment modifies the corticospinal excitability. Conference on Systems Neuroscience and Rehabilitation (2011)
  • Author(s): Kadota H, Hirashima M, Daichi N
  • Organizer: Conference on Systems Neuroscience and Rehabilitation
  • Place of Presentation: College of NRCD (Saitama)
• [Presentation] Online correction of reaching movement using sound location and pitch information in musicians and nonmusicians (2011)
  • Author(s): Fujii S, Hirashima M, Nozaki D
  • Organizer: Conference on Systems Neuroscience and Rehabilitation
  • Place of Presentation: College of NRCD (Saitama)
• [Presentation] Crosstalk in implicit assignment of visual movement error during bimanual motor learning (2011)
  • Author(s): Shoko Moriyama, Daichi Nozaki
  • Organizer: Conference on Systems Neuroscience and Rehabilitation
  • Place of Presentation: College of NRCD (Saitama)
• [Presentation] Adaptation to delay changes error sensitivity. Conference on Systems (2011)
  • Author(s): Takuya Honda, Daichi Nozaki
  • Organizer: Conference on Systems Neuroscience and Rehabilitation
  • Place of Presentation: College of NRCD (Saitama)
• [Presentation] Bimanual action coordinated by gain-field encoding of both arm's kinematics in the internal model (2011)
  • Author(s): Yokoi A, Hirashima M, Nozaki D
  • Organizer: Conference on Systems Neuroscience and Rehabilitation
  • Place of Presentation: College of NRCD (Saitama)
• [Presentation] Intermittent visual feedback can boost visuomotor learning of rhythmic movements (2010)
  • Author(s): Ikegami T., Hirashima M, Osu R, Nozaki D
  • Organizer: Advances in Computational Motor Control
  • Place of Presentation: San Diego Convention Center (USA)
  • Year and Date: 2010-11-12
• [Presentation] Crosstalk in implicit assignment of visual movement error during bimanual motor learning (2010)
  • Author(s): Shoko Moriyama, Daichi Nozaki
  • Organizer: 日本神経回路学会「脳と心のメカニズム」第11回夏のワークショップ
  • Place of Presentation: さっぽろ芸術文化の館(北海道)
  • Year and Date: 2010-07-29
• [Presentation] A gain-field encoding of both limbs kinematics revealed by the motor adaptation during bimanual reaching movement (2010)
  • Author(s): Yokoi A, Hirashima M, Nozaki D
  • Organizer: 日本神経回路学会「脳と心のメカニズム」第11回夏のワークショップ
  • Place of Presentation: さっぽろ芸術文化の館(北海道)
  • Year and Date: 2010-07-29
• [Presentation] 柔軟な両腕協調運動を可能にする脳内メカニズム (2010)
  • Author(s): 野崎大地
  • Organizer: 日立製作所基礎研究所研究会
  • Place of Presentation: 埼玉鳩山町
  • Year and Date: 2010-02-09
• [Presentation] 運動系の冗長性はどのように解消されるか?-最適化によるアプローチ- (2010)
  • Author(s): 野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] 両手運動における大脳小脳連関の変調 (2010)
  • Author(s): 荒牧勇、河内w隆紀、大須理英子、野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] 筋座標系仮説に基づく一次運動野モデルから生じる見かけ上の筋及び空間情報表現ニューロン (2010)
  • Author(s): 平島雅也、野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] 聴覚フィードバック情報に基づく到達運動のオンライン修正 (2010)
  • Author(s): 藤井進也、平島雅也、野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] 間欠的な視覚フィードバックによる周期運動学習の促進 (2010)
  • Author(s): 池上剛、平島雅也、大須理英子、野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] 両腕運動学習中の潜在的な視覚エラー割り当てにおけるクロストーク (2010)
  • Author(s): 森山翔子、野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] 両腕運動学習の汎化様式から明らかになった両腕運動情報の掛け算的情報表現 (2010)
  • Author(s): 横井惇、平易雅也、野崎大地
  • Organizer: 第4回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎コンファレンスセンター(愛知県)
• [Presentation] Crosstalk in implicit assignment of visual movement error during bimanual motor learning (2010)
  • Author(s): Shoko Moriyama, Daichi Nozaki
  • Organizer: Neuro2010
  • Place of Presentation: 神戸コンベンションセンター(兵庫県)
• [Presentation] The effect of non-veridical perception for external time lag on self-9enerated sensory stimulus perception (2010)
  • Author(s): Takuya Honda, Daichi Nozaki
  • Organizer: Neuro2010
  • Place of Presentation: 神戸コンベンションセンター(兵庫県)
• [Presentation] 両腕到達運動における両側肢の運動方向に依存した学習の汎化 (2010)
  • Author(s): 横井惇、平島雅也、野崎大地
  • Organizer: Neuro2010
  • Place of Presentation: 神戸コンベンションセンター(兵庫県)
• [Presentation] Intermittent visual feedback can boost visuomotor learning of rhythmic movements (2010)
  • Author(s): Ikegami T., Hirashima M, Osu R, Nozaki D
  • Organizer: Neuro2010
  • Place of Presentation: 神戸コンベンションセンター(兵庫県)
• [Presentation] Adaptation of wrist movements to a novel dynamical environment modifies the directional tuning of corticospinal excitability (2010)
  • Author(s): Kadota H, Hirashima M, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] Visuomotor learning for rhythmic movement is driven by errors in previous movement cycles : A system identification study (2010)
  • Author(s): Ikegami T., Hirashima M, Osu R, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] Crosstalk in implicit assignment of visual movement error during bimanual visuomotor learning (2010)
  • Author(s): Shoko Moriyama, Daichi Nozaki
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] Online correction of reaching movement by auditory feedback information (2010)
  • Author(s): Fujii S, Hirashima M, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] A gain-field encoding of both limbs kinematics revealed by the motor adaptation during bimanual reaching movement (2010)
  • Author(s): Yokoi A, Hirashima M, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] Decrease in effective connectivity from cerebellum to primary motor cortex during bimanual movements (2010)
  • Author(s): Aramaki Y, Kochiyama T, Osu R, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] Motor learning of uni- and bi-manual grip force modulation (2010)
  • Author(s): Sekiguchi H, Takeuchi S, Kadota H, Nakazawa K, Miyazaki M, Uchida S, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: San Diego Convention Center (USA)
• [Presentation] Context-dependent switching of motor control process for arm movement as revealed by the motor learning transfer within the same limb (2010)
  • Author(s): 横井惇, 平島雅也, 野崎大地
  • Organizer: Conference on Systems-neuroscience and Rehabilitation
  • Place of Presentation: Tokorozawa
• [Presentation] Switching of internal models with kinematics of contralateral limb. (2009)
  • Author(s): Nozaki D.
  • Organizer: Okazaki International mini-symposium : Neural control of eye and hand movement.
  • Place of Presentation: 岡崎
  • Year and Date: 2009-11-16
• [Presentation] Switching of internal models with kinematics of contralateral limb. (2009)
  • Author(s): 野崎大地
  • Organizer: Okazaki International mini-symposium : Neural control of eye and hand movement
  • Place of Presentation: 岡崎
  • Year and Date: 2009-11-16
• [Presentation] 二関節筋存在下での筋活動レベルの制御 (2009)
  • Author(s): 野崎大地
  • Organizer: 第21回日本運動器リハビリテーション学会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-11
• [Presentation] 運動学習から覗く脳内過程 (2009)
  • Author(s): 野崎大地
  • Organizer: 早稲田大学スポーツ科学研究センターシンポジウム「スポーツと脳2009」招待シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2009-03-14
• [Presentation] 離散運動と周期運動の制御過程の違い (2009)
  • Author(s): 池上剛、平島雅也、多賀厳太郎、野崎大地
  • Organizer: 早稲田大学スポーツ科学研究センターシンポジウム「スポーツと脳2009」
  • Place of Presentation: 東京
  • Year and Date: 2009-03-14
• [Presentation] 運動学習から覗く脳内過程 (2009)
  • Author(s): 野崎大地
  • Organizer: 日本ボバース研究会・関東ブロック研修会招待講演
  • Place of Presentation: 取手
  • Year and Date: 2009-02-28
• [Presentation] Adaptation to conflicting force fields by adopting different motor plans. (2009)
  • Author(s): Hirashima M, Nozaki D.
  • Organizer: Society for the Neural Control of Movement
  • Place of Presentation: Hawaii
• [Presentation] Similarity of various bimanual movements to unimanual movement as revealed by the motor learning transfer within the same limb. (2009)
  • Author(s): Yokoi A, Hirashima M, Nozaki D.
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago
• [Presentation] Adaptation to conflicting force fields by adopting different motor plans (2009)
  • Author(s): 平島雅也, 野崎大地
  • Organizer: Society for the Neural Control of Movement
  • Place of Presentation: Hawaii
• [Presentation] 「両腕到達運動中の脳内過程-対側の腕運動に応じた運動学習メモリ(制御過程)の切り替わり-」(シンポジウム「脳はどのよに両手の協調運動制御を実現するのか?」) (2009)
  • Author(s): 横井惇、平島雅也、野崎大地
  • Organizer: 第3回 生理学研究所「Motor Control研究会」
  • Place of Presentation: 岡崎
• [Presentation] 異なる運動計画が可能にする相反力場環境への同時適応 (2009)
  • Author(s): 平島雅也、野崎大地
  • Organizer: 第32回日本神経科学大会
  • Place of Presentation: 名古屋
• [Presentation] Delay in the restarting of motor command just after the motor inhibition. (2009)
  • Author(s): Yamanaka K, Nozaki D
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago
• [Presentation] Simultaneous adaptation to conflicting force fields by adopting different motor plans (2009)
  • Author(s): 平島雅也, 野崎大地
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago
• [Presentation] Similarity of various bimanual movements to unimanual movement as revealed by the motor learning transfer within the same limb (2009)
  • Author(s): 横井惇, 平島雅也, 野崎大地
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago
• [Presentation] Intermittent visual feedback facilitates visuomotor learning of rhythmic reaching movements (2009)
  • Author(s): Tsuyoshi Ikegami, Masaya Hirashima, Daichi Nozaki
  • Organizer: Society for Neuroscience
  • Place of Presentation: Chicago
• [Presentation] Limited transfer of learning between unimanual and bimanual skills within the same limb. (2008)
  • Author(s): Nozaki D.
  • Organizer: Annual Meeting of the Neural Control of Movement
  • Place of Presentation: Naples Beach, USA
  • Year and Date: 2008-05-02
• [Presentation] Limited transfer of learning between unimanual and bimanual skills within the same limb (2008)
  • Author(s): Nozaki D
  • Organizer: Annual Meeting of the Neural Control of Movement
  • Place of Presentation: Naples Beach, USA
  • Year and Date: 2008-05-02
• [Presentation] 運動学習から覗く脳内過程 (2008)
  • Author(s): 野崎大地
  • Organizer: COMPO研究会招待講演
  • Place of Presentation: 東京
  • Year and Date: 2008-04-21
• [Presentation] 片腕・両腕運動時の運動学習過程の数学的モデル:空問構造と時間的動態の密接な関係 (2008)
  • Author(s): 野崎大地
  • Organizer: 第2回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎
• [Presentation] 離散運動と周期運動の問の非対称な学習転移 (2008)
  • Author(s): 池上剛、平島雅也、多賀厳太郎、野崎大地
  • Organizer: 第2回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎
• [Presentation] 反対側上肢運動に応じた運動学習メモリの切り替わり (2008)
  • Author(s): 横井惇、平島雅也、野崎大地
  • Organizer: 第2回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎
• [Presentation] 上肢到達運動における座標変換と筋活動選択を行うニューラルネットワークモデル (2008)
  • Author(s): 平島雅也、野崎大地
  • Organizer: 第2回生理学研究所Motor Control研究会
  • Place of Presentation: 岡崎
• [Presentation] 到達運動における座標変換と筋活動選択を行う一次運動野のニューラルネットワークモデル (2008)
  • Author(s): 平島雅也、野崎大地
  • Organizer: 第26回日本ロボット学会学術講演会
  • Place of Presentation: 神戸
• [Presentation] Asymmetric transfer of learning between discrete and rhythmic movements (2008)
  • Author(s): Ikegami T, Hirashima M, Taga G, Nozaki D
  • Organizer: Society for Neuroscience.
  • Place of Presentation: Washington, DC.
• [Presentation] 上肢到達運動における座標変換と筋活動選択を行う皮質ニューラルネットワークモデル (2008)
  • Author(s): 平島雅也、野崎大地
  • Organizer: 計測自動制御学会システム・情報部門学術講演会
  • Place of Presentation: 姫路
• [Presentation] Contralateral limb motion-dependent motor learning in bimanual movement.
  • Author(s): Yokoi A, Hirashima M, Nozaki D
  • Organizer: Society for Neuroscience.
  • Place of Presentation: Washington, DC
• [Presentation] Coordinate transformation with muscle redundancy in cortical network: A modeling study.
  • Author(s): Hirashima M, Nozaki D
  • Organizer: Society for Neuroscience.
  • Place of Presentation: Washington, DC
• [Presentation] Spike-timing dependent plasticity in the human spinal motoneuronal pool.
  • Author(s): Obata H, Takahashi M, Nozaki D, Nakazawa K
  • Organizer: Society for Neuroscience.
  • Place of Presentation: Washington, DC
• [Remarks] 個人ホームページ
  • URL: http://www.p.u-tokyo.ac.jp/~nozaki
• [Remarks]
  • URL: http://www.p.u-tokyo.ac.jp/~nozaki
• [Remarks]
• [Remarks]
  • URL: http://www.p.u-tokyo.ac.jp~nozaki