Structure and Dynamics of Single Polymer Chain Studied by Three-dimensional Super-resolution Imaging Technique
| Project/Area Number |
20685016
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Polymer/Textile materials
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| Research Institution | Kyoto University |
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Principal Investigator |
AOKI Hiroyuki Kyoto University, 先端医工学研究ユニット, 准教授 (90343235)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥26,260,000 (Direct Cost: ¥20,200,000、Indirect Cost: ¥6,060,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
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| Keywords | 単一高分子鎖 / 表面・界面 / 蛍光顕微鏡 / 超解像 / 分子運動 / 高分子ダイナミクス |
|---|
| Research Abstract |
A super-resolution microscopy technique was developed to enable the structural analysis of polymers at a nanometric scale. A single poly(butyl methacrylate) (PBMA) chain labeled by photochromic fluorescent dye molecules was observed by the photo-activated localization microscopy (PALM), which has the spatial resolution of 15×15×80nm^3 in three dimensions. The PALM allowed us to directly examine the conformation of the individual PBMA chains.
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Report
(4 results)
Research Products
(66 results)
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[Journal Article] Photo Gel-Sol/Sol-Gel Transition and Its Patterning of a Supramolecular Hydrogel as Stimuli-Responsive Biomaterials2008
Author(s)
Shinji Matsumoto, Satoshi Yamaguchi, Shiori Ueno, Harunobu Komatsu, Masato Ikeda, Koji Ishizuka, Yuko Iko, Kazuhito V. Tabata, Hiroyuki Aoki, Shinzaburo Ito, Hiroyuki Noji. Raru Hamachi
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Journal Title
Chem. Eur. J 14
Pages: 3977-3986
Related Report
Peer Reviewed
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