Tissue engineering by using electrochemical approaches
Project/Area Number |
20686056
|
Research Category |
Grant-in-Aid for Young Scientists (A)
|
Allocation Type | Single-year Grants |
Research Field |
Biofunction/Bioprocess
|
Research Institution | University of Tsukuba |
Principal Investigator |
FUKUDA Junji University of Tsukuba, 大学院・数理物質科学研究科, 講師 (80431675)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000)
Fiscal Year 2010: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2009: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2008: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
|
Keywords | 医用化学工学 / 再生医療 / 自己組織化単分子膜 / 細胞組織工学 / バイオ関連機器 / 細胞チップ / マイクロアレイ |
Research Abstract |
This study demonstrated that cells were detached within 5 min via electrical desorption of alkane thiol self-assembled monolayers. This is the most rapid cell detachment approach compared to other previous approaches. This electrical approach could also be used to harvest cell sheets of cardiomyocytes and fibroblasts, and hepatocyte spheroids. Furthermore, this was applicable to fabricate vascular-like structures, by transferring cells to the internal surface of microchannels in hydrogel. This approach can be a fundamental tool for engineering tissues with vascular networks.
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Report
(4 results)
Research Products
(78 results)