|Budget Amount *help
¥24,700,000 (Direct Cost : ¥19,000,000、Indirect Cost : ¥5,700,000)
Fiscal Year 2011 : ¥5,850,000 (Direct Cost : ¥4,500,000、Indirect Cost : ¥1,350,000)
Fiscal Year 2010 : ¥7,020,000 (Direct Cost : ¥5,400,000、Indirect Cost : ¥1,620,000)
Fiscal Year 2009 : ¥5,720,000 (Direct Cost : ¥4,400,000、Indirect Cost : ¥1,320,000)
Fiscal Year 2008 : ¥6,110,000 (Direct Cost : ¥4,700,000、Indirect Cost : ¥1,410,000)
I developed systemic gene delivery systems for vascular diseases using polymeric micelles, composed of poly(ethylene glycol)-polycation block copolymers and plasmid DNA. I designed polymeric micelles with various intelligent functions, and they achieved an enhancement of stability in blood stream, targeting to disease regions, controlling intracellular trafficking, and effective release of encapsulated gene.