Corneal regeneration using epithelial, stromal, and endothelial precursor cells based on cellular senescence control

• Project/Area Number: 20689032
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Ophthalmology
• Research Institution: The University of Tokyo
• Principal Investigator: MIMURA Tatsuya The University of Tokyo, 研究員 (70463867)
• Co-Investigator(Renkei-kenkyūsha): USUI Tomohiko 東京大学, 大学院・医学研究科, 講師 (80282557) ; HONDA Norihiko 東京大学, 大学院・医学研究科, 大学院生 ; YOKOO Seiichi 東京大学, 大学院・医学研究科, 助教 (20345052) ; YAMAGAMI Satoru 東京大学, 大学院・医学研究科, 助教授 (10220245) ; AMANO Shiro 東京大学, 大学院・医学研究科, 教授 (80193027)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000); Fiscal Year 2010: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000); Fiscal Year 2009: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000); Fiscal Year 2008: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
• Keywords: 眼発生 / 再生医学 / 角膜再生 / 幹細胞移植 / 老化制御 / 臨床試験 / 前駆細胞 / 幹細胞 / 角膜 / 結膜

Research Abstract

We developed an adult stem cell=precursor cell isolation method (the sphere-forming assay) for corneal epithelial, stromal, and endothelial cells, which could isolate cells with differences of telomere length, telomerase activity, and characteristics reflecting senescence. We demonstrated transplantation of corneal epithelial sheet using epithelial precursors, stromal sheet using keratocyte precursors combined with gelatin hydrogel, or spheres of endothelial precursors to the cornea is a possible treatment strategy for corneal regeneration.

Research Products

• [Journal Article] Relationship between conjunctivochalasis and refractive error. (2011)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Toyono T, Mori M, Amano S.
  • Journal Title: Eye Contact Lens. 37(2) Pages: 71-78
  • Peer Reviewed
• [Journal Article] Visual prognosis and vitreous molecules after vitrectomy for macular edema with branch retinal vein occlusion. (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: Clin Ophthalmol. 5 Pages: 223-229
  • Peer Reviewed
• [Journal Article] Sudden onset of amantadine-induced reversible bilateral corneal edema in an elderly patient : Case report and literature review. (2011)
  • Author(s): Hotehama A, Mimura T, Usui T, Kawashima H, Amano S.
  • Journal Title: Jpn J Ophthalmol. 55(1) Pages: 71-74
  • NAID: 10029020683
  • Peer Reviewed
• [Journal Article] Severity and determinants of pinguecula in a hospital-based population. (2011)
  • Author(s): Mimura T, Usui T, Obata H, Yamagami S, Mori M, Funatsu H, Noma H, Dou K, Amano S.
  • Journal Title: Eye Contact Lens. 37(1) Pages: 31-35
  • Peer Reviewed
• [Journal Article] Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in macular oedema with central retinal vein occlusion. (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K, Hori S.
  • Journal Title: Curr Eye Res. 36(3) Pages: 256-263
  • Peer Reviewed
• [Journal Article] Laser treatment of giant iris cyst with nanophthalmos. (2011)
  • Author(s): Honda N, Mimura T, Hotehama A, Usui T, Sugisaki K, Fukuoka S, Amano S.
  • Journal Title: Int Ophthalmol. 31(1) Pages: 17-20
  • Peer Reviewed
• [Journal Article] Visual prognosis and vitreous molecules after vitrectomy for macular edema with branch retinal vein occlusion. (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: Clin Ophthalmol Volume: 5 Pages: 223-229
  • Peer Reviewed
• [Journal Article] Sudden onset of amantadine-induced reversible bilateral corneal edema in an elderly patient : Case report and literature review. (2011)
  • Author(s): Hotehama A, Mimura T, Usui T, Kawashima H, Amano S.
  • Journal Title: Jpn J Ophthalmol Volume: 55 Pages: 71-4
  • NAID: 10029020683
  • Peer Reviewed
• [Journal Article] Relationship between conjunctivochalasis and refractive error. (2011)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Toyono T, Mori M, Amano S.
  • Journal Title: Eye Contact Lens Volume: 37 Pages: 71-78
  • Peer Reviewed
• [Journal Article] Relation Between Total Tear IgE and Specific Serum IgE in Seasonal Allergic Conjunctivitis. (2011)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Yamamoto H, Aixinijueluo W, Amano S.
  • Journal Title: Cornea Volume: (In press)
  • Peer Reviewed
• [Journal Article] Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in macular edema with central retinal vein occlusion. (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K, Hori S.
  • Journal Title: Curr Eye Res Volume: 36 Pages: 256-263
  • Peer Reviewed
• [Journal Article] Relationship between Total Tear and Serum IgE in Allergic Conjunctivitis. (2011)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Yamamoto H, Aixinjueluo W, Amano S.
  • Journal Title: Int Arch Allergy Immunol Volume: 154 Pages: 349-352
  • Peer Reviewed
• [Journal Article] Laser treatment of giant iris cyst with nanophthalmos. (2011)
  • Author(s): Honda N, Mimura T, Hotehama A, Usui T, Sugisaki K, Fukuoka S, Amano S.
  • Journal Title: Int Ophthalmol Volume: 31 Pages: 17-20
  • Peer Reviewed
• [Journal Article] Role of soluble vscular endothelial growth factor receptor-2 in macular oedema with central retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: Br J Ophthalmol. [Epub ahead of print]
  • Peer Reviewed
• [Journal Article] Vitreous inflammatory factors and macular oedema. (2010)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S.
  • Journal Title: Br J Ophthalmol. [Epub ahead of print]
  • Peer Reviewed
• [Journal Article] Bilateral limbal stem cell deficiency with chromosomal translocation of 3p and 9p. (2010)
  • Author(s): Usui T, Nakagawa S, Yokoo S, Mimura T, Yamagami S, Amano S.
  • Journal Title: Jpn J Ophthalmol. 54 Pages: 357-358
  • NAID: 10027204707
  • Peer Reviewed
• [Journal Article] Isolation of adult progenitor cells with neuronal potential from rabbit corneal epithelial cells in serum-and feeder layer-free culture conditions. (2010)
  • Author(s): Mimura T, Yamagami S, Uchida S, Yokoo S, Ono K, Usui T, Amano S.
  • Journal Title: Mol Vis. 16 Pages: 1712-1719
  • Peer Reviewed
• [Journal Article] Pinguecula and contact lenses. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Yamamoto H, Obata H, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Eye (Lond). 24 Pages: 1685-1691
  • Peer Reviewed
• [Journal Article] Rapid immunochromatography of total tear IgE in allergic conjunctivitis with allerwatch. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Aixinjueluo W, Yamamoto H, Amano S.
  • Journal Title: J Investig Allergol Clin Immunol. 20 Pages: 627-628
  • Peer Reviewed
• [Journal Article] Biology of corneal endothelial cells in vivo and in vitro. (2010)
  • Author(s): Amano S, Kaji Y, Mimura T.
  • Journal Title: Jpn J Ophthalmol. 54(3) Pages: 211-214
  • NAID: 10027204090
  • Peer Reviewed
• [Journal Article] Contact lens-induced subconjunctival hemorrhage. (2010)
  • Author(s): Mimura T, Yamagami S, Mori M, Funatsu H, Usui T, Noma H, Amano S.
  • Journal Title: Am J Ophthalmol. 150(5) Pages: 656-665
  • Peer Reviewed
• [Journal Article] Relationship between total tear and serum IgE in allergic conjunctivitis. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Yamamoto H, Aixinjueluo W, Amano S.
  • Journal Title: Int Arch Allergy Immunol. 154(4) Pages: 349-352
  • Peer Reviewed
• [Journal Article] Influence of Macular Microcirculation and Retinal Thickness on Visual Acuity in Patients With Branch Retinal Vein Occlusion and Macular Edema. (2010)
  • Author(s): Noma H, Funatsu H, Harino S, Nagaoka T, Mimura T, Hori S.
  • Journal Title: Jpn J Ophthalmol. 54(5) Pages: 430-434
  • NAID: 10027665751
  • Peer Reviewed
• [Journal Article] Pigment epithelium-derived factor and vascular endothelial growth factor in branch retinal vein occlusion with macular edema. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Eguchi S, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol. 248(11) Pages: 1559-1565
  • Peer Reviewed
• [Journal Article] Increase of aqueous inflammatory factors in macular edema with branch retinal vein occlusion : a case control study. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K.
  • Journal Title: J Inflamm (Lond). 7(1) Pages: 44-44
  • NAID: 120007164935
  • Peer Reviewed
• [Journal Article] Immunochromatographic assay for measurement of total IgE in tears, nasal mucus, and saliva of patients with allergic rhinoconjunctivitis. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Aixinjueluo W, Funatsu H, Noma H, Amano S.
  • Journal Title: J Asthma. 47(10) Pages: 1153-1160
  • Peer Reviewed
• [Journal Article] High-dose steroid therapy for idiopathic optic perineuritis : a case series. (2010)
  • Author(s): Tatsugawa M, Noma H, Mimura T, Funatsu H.
  • Journal Title: J Med Case Reports 4(1) Pages: 404-404
  • NAID: 120007164936
  • Peer Reviewed
• [Journal Article] Visual acuity and foveal thickness after vitrectomy for macular edema associated with branch retinal vein occlusion : a case series. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: BMC Ophthalmol. 10(1) Pages: 11-11
  • NAID: 120007164934
  • Peer Reviewed
• [Journal Article] Association between macular microcirculation and soluble intercellular adhesion molecule-1 in patients with macular edema and retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Sakata K, Mimura T, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol. 248 Pages: 1515-1518
  • Peer Reviewed
• [Journal Article] Corneal Epithelial MT1-MMP Inhibits Vascular Endothelial Cell Proliferation and Migration. (2010)
  • Author(s): Azar DT, Casanova FH, Mimura T, Jain S, Zhou Z, Han KY, Chang JH.
  • Journal Title: Cornea. 29(3) Pages: 321-330
  • Peer Reviewed
• [Journal Article] Effect of latanoprost on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase-1 on the ocular surface. (2010)
  • Author(s): Honda N, Miyai T, Nejima R, Miyata K, Mimura T, Usui T, Aihara M, Araie M, Amano S.
  • Journal Title: Arch Ophthalmol. 128(4) Pages: 466-471
  • Peer Reviewed
• [Journal Article] Selective isolation of young cells from human corneal endothelium by the sphere-forming assay. (2010)
  • Author(s): Mimura T, Yamagami S, Yokoo S, Usui T, Amano S.
  • Journal Title: Tissue Eng Part C Methods. 16(4) Pages: 803-812
  • Peer Reviewed
• [Journal Article] Macular microcirculation before and after vitrectomy for macular edema with branch retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Sakata K, Mimura T, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol. 248(3) Pages: 443-445
  • Peer Reviewed
• [Journal Article] Visual acuity and foveal thickness after vitrectomy for macular edema. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K.
  • Journal Title: Ophthalmologica. 224(6) Pages: 367-373
  • Peer Reviewed
• [Journal Article] Extended long-term results of penetrating keratoplasty for keratoconus. (2010)
  • Author(s): Fukuoka S, Honda N, Ono K, Mimura T, Usui T, Amano S.
  • Journal Title: Cornea. 29(5) Pages: 528-530
  • Peer Reviewed
• [Journal Article] Aqueous humor levels of vasoactive molecules correlate with vitreous levels and macular edema in central retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Hori S.
  • Journal Title: Eur J Ophthalmol. 20(2) Pages: 402-409
  • Peer Reviewed
• [Journal Article] Ocular involvement by EBV-positive diffuse large B-cell lymphoma of the elderly, a new disease entity in the WHO classification. (2010)
  • Author(s): Tsuji H, Tamura M, Yokoyama M, Takeuchi K, Mimura T.
  • Journal Title: Arch Ophthalmol. 128(2) Pages: 258-259
  • Peer Reviewed
• [Journal Article] Primary epithelioid haemangioendothelioma of the eyelid. (2010)
  • Author(s): Tsuji H, Kanda H, Kashiwagi H, Mimura T.
  • Journal Title: Br J Ophthalmol 94 Pages: 261-262
  • Peer Reviewed
• [Journal Article] Location and extent of subconjunctival hemorrhage. (2010)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Fukuoka S, Hotta H, Amano S.
  • Journal Title: Ophthalmologica. 224(2) Pages: 90-95
  • Peer Reviewed
• [Journal Article] Increase of vascular endothelial growth factor and interleukin-6 in the aqueous humour of patients with macular oedema and central retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Sone T, Hori S.
  • Journal Title: Acta Ophthalmol. 88(6) Pages: 646-651
  • Peer Reviewed
• [Journal Article] Recent causes of subconjunctival hemorrhage. (2010)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Ophthalmologica 224 Pages: 133-137
  • Peer Reviewed
• [Journal Article] Rapid immunochromatography of total tear immunoglobulin E in allergic conjunctivitis with Allerwatch. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Aixinjueluo W, Yamamoto H, Amano S.
  • Journal Title: J Investig Allergol Clin Immunol. Volume: 20 Pages: 627-628
  • Peer Reviewed
• [Journal Article] Severity and determinants of pinguecula in a hospital-based population. (2010)
  • Author(s): Mimura T, Usui T, Obata H, Yamagami S, Mori M, Funatsu H, Noma H, Dou K, Amano S.
  • Journal Title: Eye Contact Lens Volume: 37 Pages: 31-35
  • Peer Reviewed
• [Journal Article] High-dose steroid therapy for idiopathic optic perineuritis : a case series. (2010)
  • Author(s): Tatsugawa M, Noma H, Mimura T, Funatsu H
  • Journal Title: J Med Case Reports Volume: 4 Pages: 404-404
  • NAID: 120007164936
  • Peer Reviewed
• [Journal Article] Role of soluble vascular endothelial growth factor receptor-2 in macular oedema with central retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: Br J Ophthalmol Volume: (In press)
  • Peer Reviewed
• [Journal Article] Influence of macular microcirculation and retinal thickness on visual acuity in patients with branch retinal vein occlusion and macular edema. (2010)
  • Author(s): Noma H, Funatsu H, Harino S, Nagaoka T, Mimura T, Hori S.
  • Journal Title: Jpn J Ophthalmol Volume: 54 Pages: 430-434
  • NAID: 10027665751
  • Peer Reviewed
• [Journal Article] Rapid Immunochromatographic Measurement of Specific Tear Immunoglobulin E in Moderate to Severe Cases of Allergic Conjunctivitis With Immfast Check J1 in the Spring. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Amano S.
  • Journal Title: Cornea Volume: (In press)
  • Peer Reviewed
• [Journal Article] Immunochromatographic assay for measurement of total IgE in tears, nasal mucus, and saliva of patients with allergic rhinoconjunctivitis. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Aixinjueluo W, Funatsu H, Noma H, Amano S.
  • Journal Title: J Asthma Volume: 47 Pages: 1153-1160
  • Peer Reviewed
• [Journal Article] Vitreous inflammatory factors and macular oedema. (2010)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S.
  • Journal Title: Br J Ophthalmol. Volume: (In press)
  • Peer Reviewed
• [Journal Article] Pinguecula and contact lenses. (2010)
  • Author(s): Mimura T, Usui T, Mori M, Yamamoto H, Obata H, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Eye (Lond) Volume: 24 Pages: 1685-1691
  • Peer Reviewed
• [Journal Article] Isolation of adult progenitor cells with neuronal potential from rabbit corneal epithelial cells in serum- and feeder layer-free culture conditions. (2010)
  • Author(s): Mimura T, Yamagami S, Uchida S, Yokoo S, Ono K, Usui T, Amano S.
  • Journal Title: Mol Vis Volume: 16 Pages: 1712-1719
  • Peer Reviewed
• [Journal Article] Increase of aqueous inflammatory factors in macular edema with branch retinal vein occlusion : a case control study. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K.
  • Journal Title: J Inflamm (Lond) Volume: 7 Pages: 44-44
  • NAID: 120007164935
  • Peer Reviewed
• [Journal Article] Pigment epithelium-derived factor and vascular endothelial growth factor in branch retinal vein occlusion with macular edema. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Eguchi S, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol Volume: 248 Pages: 1559-1565
  • Peer Reviewed
• [Journal Article] Contact lens-induced subconjunctival hemorrhage. (2010)
  • Author(s): Mimura T, Yamagami S, Mori M, Funatsu H, Usui T, Noma H, Amano S.
  • Journal Title: Am J Ophthalmol Volume: 150 Pages: 656-665
  • Peer Reviewed
• [Journal Article] Bilateral limbal stem cell deficiency with chromosomal translocation of 3p and 9p. (2010)
  • Author(s): Usui T, Nakagawa S, Yokoo S, Mimura T, Yamagami S, Amano S.
  • Journal Title: Jpn J Ophthalmol Volume: 54 Pages: 357-358
  • NAID: 10027204707
  • Peer Reviewed
• [Journal Article] Biology of corneal endothelial cells in vivo and in vitro. (2010)
  • Author(s): Amano S, Kaji Y, Mimura T.
  • Journal Title: Jpn J Ophthalmol Volume: 54 Pages: 211-214
  • NAID: 10027204090
  • Peer Reviewed
• [Journal Article] Visual acuity and foveal thickness after vitrectomy for macular edema. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K.
  • Journal Title: Ophthalmologica Volume: 224 Pages: 367-373
  • Peer Reviewed
• [Journal Article] Visual acuity and foveal thickness after vitrectomy for macular edema associated with branch retinal vein occlusion : a case series. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: BMC Ophthalmol Volume: 10 Pages: 11-11
  • NAID: 120007164934
  • Peer Reviewed
• [Journal Article] Effect of latanoprost on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase 1 on the ocular surface. (2010)
  • Author(s): Honda N, Miyai T, Nejima R, Miyata K, Mimura T, Usui T, Aihara M, Araie M, Amano S.
  • Journal Title: Arch Ophthalmol Volume: 128 Pages: 466-471
  • Peer Reviewed
• [Journal Article] Association between macular microcirculation and soluble intercellular adhesion molecule-1 in patients with macular edema and retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Sakata K, Mimura T, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol Volume: 248 Pages: 1515-1518
  • Peer Reviewed
• [Journal Article] Extended long-term results of penetrating keratoplasty for keratoconus. (2010)
  • Author(s): Fukuoka S, Honda N, Ono K, Mimura T, Usui T, Amano S.
  • Journal Title: Cornea Volume: 29 Pages: 528-530
  • Peer Reviewed
• [Journal Article] Ocular involvement by epstein-barr virus-positive diffuse large B-cell lymphoma of the elderly : a new disease entity in the world health organization classification. (2010)
  • Author(s): Tsuji H, Tamura M, Yokoyama M, Takeuchi K, Mimura T.
  • Journal Title: Arch Ophthalmol Volume: 128 Pages: 258-259
  • Peer Reviewed
• [Journal Article] Primary epithelioid haemangioendothelioma of the eyelid. (2010)
  • Author(s): Tsuji H, Kanda H, Kashiwagi H, Mimura T.
  • Journal Title: Br J Ophthalmol Volume: 94 Pages: 261-262
  • Peer Reviewed
• [Journal Article] Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration. (2010)
  • Author(s): Azar DT, Casanova FH, Mimura T, Jain S, Zhou Z, Han KY, Chang JH.
  • Journal Title: Cornea Volume: 29 Pages: 321-330
  • Peer Reviewed
• [Journal Article] Aqueous humor levels of vasoactive molecules correlate with vitreous levels and macular edema in central retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Hori S.
  • Journal Title: Eur J Ophthalmol Volume: 20 Pages: 402-409
  • Peer Reviewed
• [Journal Article] Macular microcirculation before and after vitrectomy for macular edema with branch retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Sakata K, Mimura T, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol Volume: 248 Pages: 443-445
  • Peer Reviewed
• [Journal Article] Selective isolation of young cells from human corneal endothelium by the sphere-forming assay. (2010)
  • Author(s): Mimura T, Yamagami S, Yokoo S, Usui T, Amano S.
  • Journal Title: Tissue Eng Part C Methods Volume: 16 Pages: 803-812
  • Peer Reviewed
• [Journal Article] Recent causes of subconjunctival hemorrhage. (2010)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Ophthalmologica Volume: 224 Pages: 133-137
  • Peer Reviewed
• [Journal Article] Location and extent of subconjunctival hemorrhage. (2010)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Fukuoka S, Hotta H, Amano S
  • Journal Title: Ophthalmologica Volume: 224 Pages: 90-95
  • Peer Reviewed
• [Journal Article] Increase of vascular endothelial growth factor and interleukin-6 in the aqueous humour of patients with macular oedema and central retinal vein occlusion. (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Sone T, Hori S.
  • Journal Title: Acta Ophthalmol Volume: 88 Pages: 646-651
  • Peer Reviewed
• [Journal Article] Location and extent of subconjunctival hemorrhage (2010)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Fukuoka S, Hotta H, Amano S.
  • Journal Title: Ophthalmologica 224 Pages: 90-95
  • Peer Reviewed
• [Journal Article] Recent causes of subconjunctival hemorrhage (2010)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Ophthalmologica 224 Pages: 133-137
  • Peer Reviewed
• [Journal Article] Aqueous humor levels of vasoactive molecules correlate with vitreous levels and macular edema in central retinal vein occlusion (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Hori S
  • Journal Title: Eur J Ophthalmol 20 Pages: 402-409
  • Peer Reviewed
• [Journal Article] Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration (2010)
  • Author(s): Azar DT, Casanova FH, Mimura T, Jain S, Zhou Z, Han KY, Chang JH.
  • Journal Title: Cornea 29 Pages: 321-330
  • Peer Reviewed
• [Journal Article] Primary epithelioid haemangioendothelioma of the eyelid (2010)
  • Author(s): Tsuji H, Kanda H, Kashiwagi H, Mimura T.
  • Journal Title: Br J Ophthalmol 94 Pages: 261-262
  • Peer Reviewed
• [Journal Article] Ocular involvement by epstein-barr virus-positive diffuse large B-cell lymphoma of the elderly : a new disease entity in the world health organization classification (2010)
  • Author(s): Tsuji H, Tamura M, Yokoyama M, Takeuchi K Mimura T.
  • Journal Title: Arch Ophthalmol. 128 Pages: 258-259
  • Peer Reviewed
• [Journal Article] Extended long-term results of penetrating keratoplasty for keratoconus (2010)
  • Author(s): Fukuoka S, Honda N, Ono K, Mimura T, Usui T, Amano S.
  • Journal Title: Cornea 29 Pages: 528-530
  • Peer Reviewed
• [Journal Article] Association between macular microcirculation and soluble intercellular adhesion molecule-1 in patients with macular edema and retinal vein occlusion (2010)
  • Author(s): Noma H, Funatsu H, Sakata K, Mimura T, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol. 23(in press)
  • Peer Reviewed
• [Journal Article] Effect of latanoprost on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase 1 on the ocular surface (2010)
  • Author(s): Honda N, Miyai T, Nejima R, Miyata K, Mimura T, Usui T, Aihara M, Araie M, Amano S.
  • Journal Title: Arch Ophthalmol. 128 Pages: 466-471
  • Peer Reviewed
• [Journal Article] Visual acuity and foveal thickness after vitrectomy for macular edema associated with branch retinal vein occlusion : a case series (2010)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K.
  • Journal Title: BMC Ophthalmol 10 Pages: 11-11
  • NAID: 120007164934
  • Peer Reviewed
• [Journal Article] Unusual orbital lymphoma undetectable by magnetic resonance imaging : a case report. (2009)
  • Author(s): Tatsugawa M, Noma H, Mimura T, Funatsu H.
  • Journal Title: J Med Case Reports. 3 Pages: 104-104
  • NAID: 120007164933
  • Peer Reviewed
• [Journal Article] Severe hyperopic shift and irregular astigmatism after radial keratotomy. (2009)
  • Author(s): Mimura T, Fujimura S, Yamagami S, Usui T, Honda N, Shirakawa R, Fukuoka S, Amano S.
  • Journal Title: Eye Contact Lens. 35(6) Pages: 345-347
  • Peer Reviewed
• [Journal Article] Relationship between myopia and allergen-specific serum IgE levels in patients with allergic conjunctivitis. (2009)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Clin Experiment Ophthalmol. 37 Pages: 670-677
  • Peer Reviewed
• [Journal Article] Descemet stripping automated endothelial keratoplasty using cultured corneal endothelial cells in a rabbit model. (2009)
  • Author(s): Honda N, Mimura T, Usui T, Amano S.
  • Journal Title: Arch Ophthalmol. 127(10) Pages: 1321-1326
  • Peer Reviewed
• [Journal Article] MT1-MMP-mediated cleavage of decorin in corneal angiogenesis. (2009)
  • Author(s): Mimura T, Han KY, Onguchi T, Chang JH, Kim TI, Kojima T, Zhou Z, Azar DT.
  • Journal Title: J Vasc Res. 46(6) Pages: 541-550
  • Peer Reviewed
• [Journal Article] Subconjunctival hemorrhage and conjunctivochalasis. (2009)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Shirakawa R, Hotta H, Amano S.
  • Journal Title: Ophthalmology. 116(10) Pages: 1880-1886
  • Peer Reviewed
• [Journal Article] Conjunctivochalasis and contact lenses. (2009)
  • Author(s): Mimura T, Usui T, Yamamoto H, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Amano S.
  • Journal Title: Am J Ophthalmol. 148(1) Pages: 20-25
  • Peer Reviewed
• [Journal Article] Macular Microcirculation and Macular Oedema in Branch Retinal Vein Occlusion. (2009)
  • Author(s): Noma H, Funatsu H, Sakata K, Harino S, Nagaoka T, Mimura T, Sone T, Hori S.
  • Journal Title: Br J Ophthalmol. 93(5) Pages: 630-633
  • Peer Reviewed
• [Journal Article] Primary orbital lymphomatoid granulomatosis. (2009)
  • Author(s): Araki F, Mimura T, Fukuoka S, Tsuji H, Izutsu K, Yamamoto H, Takazawa Y, Kojima T.
  • Journal Title: Br J Ophthalmol. 93(4) Pages: 554-556
  • Peer Reviewed
• [Journal Article] Vitreous levels of interleukin-6 and vascular endothelial growth factor in macular edema with central retinal vein occlusion. (2009)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Hori S.
  • Journal Title: Ophthalmology. 116(1) Pages: 87-93
  • Peer Reviewed
• [Journal Article] Association of vitreous inflammatory factors with diabetic macular edema. (2009)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S, Hori S.
  • Journal Title: Ophthalmology. 116(1) Pages: 73-79
  • Peer Reviewed
• [Journal Article] Changes in foveal thickness after vitrectomy for macular edema with branch retinal vein occlusion and intravitreal vascular endothelial growth factor. (2009)
  • Author(s): Yamasaki M, Noma H, Funatsu H, Minamoto A, Mimura T, Shimada K, Yamashita H, Kiuchi Y.
  • Journal Title: Int Ophthalmol. 29 Pages: 161-167
  • Peer Reviewed
• [Journal Article] Changes of conjunctivochalasis with age in a hospital-based study. (2009)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Mimura Y, Noma H, Honda N, Amano S.
  • Journal Title: Am J Ophthalmol. 147(1) Pages: 171-177
  • Peer Reviewed
• [Journal Article] Association between serum lipoprotein (a) level and progression of non-proliferative diabetic retinopathy in Type 2 diabetes. (2009)
  • Author(s): Funatsu H, Shimizu E, Noma H, Mimura T, Hori S.
  • Journal Title: Acta Ophthalmol. 87(5) Pages: 501-505
  • Peer Reviewed
• [Journal Article] Macular microcirculation in hypertensive patients with and without branch retinal vein occlusion. (2009)
  • Author(s): Noma H, Funatsu H, Sakata K, Harino S, Mimura T, Hori S.
  • Journal Title: Acta Ophthalmol. 87(6) Pages: 638-642
  • Peer Reviewed
• [Journal Article] Relationship between refraction and allergic conjunctivitis. (2009)
  • Author(s): Mimura T, Mimura Y, Arimoto A, Amano S, Yamagami S, Funatsu H, Usui T, Noma H, Honda N, Okamoto S.
  • Journal Title: Eye. 23(1) Pages: 63-66
  • Peer Reviewed
• [Journal Article] Relationship between refraction and allergic conjunctivitis (2009)
  • Author(s): Mimura T, Mimura Y, Arimoto A, Amano S, Yamagami S, Funatsu H, Usui T, Noma H, Honda N, Okamoto S.
  • Journal Title: Eye(Loud) 23 Pages: 63-66
  • Peer Reviewed
• [Journal Article] Changes of conjunctivochalasis with age in a hospital-based study (2009)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Mimura Y, Noma H, Honda N, Amano S.
  • Journal Title: Am J Ophthalmol. 147 Pages: 171-177
  • Peer Reviewed
• [Journal Article] Association of vitreous inflammatory factors with diabetic macular edema (2009)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S, Hori S.
  • Journal Title: Ophthalmology 116 Pages: 73-79
  • Peer Reviewed
• [Journal Article] Vitreous levels of interleukin-6 and vascular endothelial growth factor in macular edema with central retinal vein occlusion (2009)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Hori S.
  • Journal Title: Ophthalmology 116 Pages: 87-93
  • Peer Reviewed
• [Journal Article] Primary orbital lymphomatoid granulomatosis (2009)
  • Author(s): Araki F, Mimura T, Fukuoka S, Tsuji H, Izutsu K, Yamamoto H, Takazawa Y, Kojima T.
  • Journal Title: Br J Ophthalmol. 93 Pages: 554-556
  • Peer Reviewed
• [Journal Article] Macular Microcirculation and Macular Oedema in Branch Retinal Vein Occlusion (2009)
  • Author(s): Noma H, Funatsu H, Sakata K, Harino S, Nagaoka T, Mimura T, Sone T, Hori S.
  • Journal Title: Br J Ophthalmol. 93 Pages: 630-633
  • Peer Reviewed
• [Journal Article] Conjunctivochalasis and contact lenses (2009)
  • Author(s): Mimura T, Usui T, Yamamoto H, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Amano S.
  • Journal Title: Am J Ophthalmol. 148 Pages: 20-25
  • Peer Reviewed
• [Journal Article] Increase of vascular endothelial growth factor and interleukin-6 in the aqueous humour of patients with macular oedema and central retinal veinocclusion (2009)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Sone T, Hori S.
  • Journal Title: Acta Ophthalmologica 26(in press)
  • Peer Reviewed
• [Journal Article] MT1-MMP-mediated cleavage of decorin in corneal angiogenesis (2009)
  • Author(s): Mimura T, Han KY, Onguchi T, Chang JH, Kim TI, Kojima T, Zhou Z, Azar DT.
  • Journal Title: J Vasc Res. 46 Pages: 541-550
  • Peer Reviewed
• [Journal Article] Subconjunctival hemorrhage and conjunctivochalasis (2009)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Shirakawa R, Hotta H, Amano S.
  • Journal Title: Ophthalmology 116 Pages: 1880-1886
  • Peer Reviewed
• [Journal Article] Relationship between myopia and allergen-specific serum IgE levels in patients with allergic conjunctivitis (2009)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Clin Experiment Ophthalmol 37 Pages: 670-677
  • Peer Reviewed
• [Journal Article] Severe hyperopic shift and irregular astigmatism after radial keratotomy (2009)
  • Author(s): Mimura T, Fujimura S, Yamagami S, Usui T, Honda N, Shirakawa R, Fukuoka S, Amano S.
  • Journal Title: Eye Contact Lens. 35 Pages: 345-347
  • Peer Reviewed
• [Journal Article] Descemet stripping automated endothelial keratoplasty using cultured corneal endothelial cells in a rabbit model (2009)
  • Author(s): Honda N, Mimura T, Usui T, Amano S.
  • Journal Title: Arch Ophthalmol 127 Pages: 1321-1326
  • Peer Reviewed
• [Journal Article] Selective Isolation of Young Cells from Human Corneal Endothelium by the Sphere-Forming Assay (2009)
  • Author(s): Mimura T, Yamagami S, Yokoo S, Usui T, Amano S.
  • Journal Title: Tissue Eng Part C Methods 23(in press)
  • Peer Reviewed
• [Journal Article] Unusual orbital lymphoma undetectable by magnetic resonance imaging : a case report (2009)
  • Author(s): Tatsugawa M, Noma H, Mimura T, Funatsu H.
  • Journal Title: Med Case Reports 3 Pages: 3-3
  • NAID: 120007164933
  • Peer Reviewed
• [Journal Article] Macular microcirculation before and after vitrectomy for macular edema with branch retinal vein occlusion (2009)
  • Author(s): Noma H, Funatsu H, Sakata K, Mimura T, Hori S.
  • Journal Title: Graefes Arch Clin Exp Ophthalmol 248 Pages: 443-445
  • Peer Reviewed
• [Journal Article] Changes of conjunetivochalasis with age in a hospital-based study (2009)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Mimura Y, Noma H, Honda N, Amano S.
  • Journal Title: Am J Ophthalmol 147 Pages: 171-177
  • Peer Reviewed
• [Journal Article] Recent causes of subconjunctival hemorrhage (2009)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Amano S.
  • Journal Title: Ophthalmologica (in press)
  • Peer Reviewed
• [Journal Article] Association of vitreous inflammatory factors with diabetic macular edema. (2009)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S, Hori S.
  • Journal Title: Ophthalmology 116 Pages: 73-9
  • Peer Reviewed
• [Journal Article] Primary orbital lymphomatoid granulomatosis (2009)
  • Author(s): Araki F, Mimura T, Fukuoka S, Tsuji H, Izutsu K., Yamamoto H, Takazawa Y, Kojima T.
  • Journal Title: Br J Ophthalmol (in press)
  • Peer Reviewed
• [Journal Article] Effect of MT1-MMP deficiency and overexpression in corneal Keratocytes on vascular endothelial cell migration and proliferation (2009)
  • Author(s): Azar DT, Fabio C, Mimura T, Jain S, Chang JH.
  • Journal Title: Curr Eye Res. 33 Pages: 954-62
  • Peer Reviewed
• [Journal Article] Increase of vascular endothelial growth factor and interleukin-6 in the aqueous humour of patients with macular oedema and central retinal vein occlusion (2009)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Sone T, Hori S.
  • Journal Title: Acta Ophthalmologica (in press)
  • Peer Reviewed
• [Journal Article] Macular Microcirculation and Macular Oedema in Branch Retinal Vein Occlusion. (2009)
  • Author(s): Noma H, Funatsu H, Sakata K, Harino S. Nagaoka T, Mimura T, Sone T, Hori. S.
  • Journal Title: Br J Ophthalmol Epub ahead of print
  • Peer Reviewed
• [Journal Article] Location and extent of subconjunctival hemorrhage (2009)
  • Author(s): Mimura T, Yamagami S, Usui T, Funatsu H, Noma H, Honda N, Fukuoka S, Hotta H, Amano
  • Journal Title: Ophthalmologica (in press)
  • Peer Reviewed
• [Journal Article] Conjunctivochalasis and contact lenses (2009)
  • Author(s): Mimura T, Usui T, Yamamoto H, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Amano S.
  • Journal Title: Am J Ophthalmol (in press)
  • Peer Reviewed
• [Journal Article] Subconjunctival hemorrhage and conjunctivochalasis. (2009)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Honda N, Fukuoka S, Shirakawa R, Hotta H, Amano S.
  • Journal Title: Ophthalmology (in press)
  • Peer Reviewed
• [Journal Article] Effect of MT1-MMP deficiency and overexpression in corneal Keratocytes on vascular endothelial cell migration and proliferation. (2008)
  • Author(s): Azar DT, Fabio C, Mimura T, Jain S, Chang JH.
  • Journal Title: Curr Eye Res. 33 Pages: 954-962
  • Peer Reviewed
• [Journal Article] Tissue Engineering of Corneal Stroma with Rabbit Fibroblast Precursors and Gelatin Hydrogels. (2008)
  • Author(s): Mimura T, Amano S, Yokoo S, Uchida S, Yamagami S, Usui T, Kimura Y, Tabata Y.
  • Journal Title: Mol Vis. 14 Pages: 1819-1828
  • NAID: 120001851020
  • Peer Reviewed
• [Journal Article] In vivo confocal microscopy of hereditary sensory and autonomic neuropathy. (2008)
  • Author(s): Mimura T, Amano S, Fukuoka S, Honda N, Arita R, Ochiai M, Yanagisawa M, Usui T, Ono K, Araki F, Yamagami S, Araie M, Awaya Y.
  • Journal Title: Curr Eye Res. 33(11) Pages: 940-945
  • Peer Reviewed
• [Journal Article] Changes in vascular endothelial growth factor in the vitreous cavity after vitrectomy for macular oedema secondary to retinal vein occlusion. (2008)
  • Author(s): Noma H, Funatsu H, Mimura T, Hori S.
  • Journal Title: Eur J Ophthalmol 18(6) Pages: 1017-1019
  • Peer Reviewed
• [Journal Article] In vivo confocal microscopy of human cornea covered with human amniotic membrane. (2008)
  • Author(s): Mimura T, Yamagami S, Usui T, Honda N, Araki F, Amano S.
  • Journal Title: Jpn J Ophthalmol 52(6) Pages: 493-496
  • NAID: 10025149013
  • Peer Reviewed
• [Journal Article] Isolation and distribution of rabbit keratocyte precursors (2008)
  • Author(s): Mimura T, Amano S, Yokoo S, Uchida S, Usui T, Yamagami S.
  • Journal Title: Mol Vision 14 Pages: 197-203
  • Peer Reviewed
• [Journal Article] Macular microcirculation in hypertensive patients with and without branch retinal (2008)
  • Author(s): Noma H, Funatsu H, Sakata K, Harino S, Mimura T, Hori S.
  • Journal Title: Acta Ophthalmol (Epub ahead)
  • Peer Reviewed
• [Journal Article] In vivo confocal microscopy of human cornea covered with human amniotic membra (2008)
  • Author(s): Mimura T, Yamagami S, Usui T, Honda N, Araki F, Amano S.
  • Journal Title: Jpn J Ophthalmol 2 Pages: 493-6
  • Peer Reviewed
• [Journal Article] Changes in vascular endothelial growth factor in the vitreous cavity after vitrectomy for macular oedema secondary to retinal vein occlusion (2008)
  • Author(s): Noma H, Funatsu H, Mimura T, Hori S.
  • Journal Title: Eur J Ophthalmol 8 Pages: 1017-9
  • Peer Reviewed
• [Journal Article] Association between serum lipoprotein (a)level and progression of non-proliferative diabetic retinopathy in Type 2 diabetes (2008)
  • Author(s): Funatsu H, Shimizu E, Noma H, Mimura T, Hori S
  • Journal Title: Acta Ophthalmol Epub ahead of print
  • Peer Reviewed
• [Journal Article] Changes in foveal thickness after vitrectomy for macular edema with branch retinal vein occlusion and intravitreal vascular endothelial growth factor (2008)
  • Author(s): Yamasaki M, Noma H, Funatsu H, Minamoto A, Mimura T, Shimada K, Yamashita H, Kiuchi Y.
  • Journal Title: Int Ophthalmol Epub ahead of print
  • Peer Reviewed
• [Journal Article] In vivo confocal microscopy of hereditary sensory and autonomic neuropathy (2008)
  • Author(s): Mimura T, Amano S, Fukuoka S, Honda N, Arita R, Ochiai M, Yanagisawa M, Usui T, Ono K, Araki F, Yamagami S, Araie M, Awaya Y.
  • Journal Title: Curr Eye Res 33 Pages: 940-5
  • Peer Reviewed
• [Journal Article] Tissue Engineering of Corneal Stroma with Rabbit Fibroblast Precursors and Gelatin Hydrogels (2008)
  • Author(s): Mimura T, Amano S, Yokoo S, Uchida S, Yamagami S, Usui T, Kimura Y, Tabata Y.
  • Journal Title: Mol Vis. 14 Pages: 1819-28
  • NAID: 120001851020
  • Peer Reviewed
• [Journal Article] Conjunctivochalasis : associations with pinguecula in a hospital-based study.
  • Author(s): Mimura T, Mori M, Obata H, Usui T, Yamagami S, Funatsu H, Noma H, Amano S.
  • Journal Title: Acta Ophthalmol. in press.
  • Peer Reviewed
• [Journal Article] Functional-morphological correlates in patients with branch retinal vein occlusion and macular edema.
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Shimada K.
  • Journal Title: Retina in press.
  • Peer Reviewed
• [Journal Article] Specifftear IgE in patients with moderate-to-severe autumnal allergic conjunctivitis.
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Amano S.
  • Journal Title: Int Arch Allergy Immunol. in press.
  • Peer Reviewed
• [Journal Article] Role of MT1-MMP on anti-angiogenic proteoglycan
  • Author(s): Mimura T, Chang JH, Kim TI, Onguchi T, Kojima T, Sakimoto T, Azar DT.
  • Journal Title: Decorin, in corneal angiogenesis Cornea in press
  • Peer Reviewed
• [Journal Article] Vitreous Inflammatory Factors in Macular Edema With Central Retinal Vein Occlusion.
  • Author(s): Noma H, Funatsu H, Harino S, Mimura T, Eguchi S, Hori S.
  • Journal Title: Jpn J Ophthalmol in press.
  • NAID: 10029021322
  • Peer Reviewed
• [Journal Article] Relation between total tear IgE and specific serum IgE in seasonal allergic conjunctivitis.
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Yamamoto H, Aixinjueluo W, Amano S.
  • Journal Title: Cornea in press.
  • Peer Reviewed
• [Journal Article] Rapid immunochromatographic measurement of specific tear IgE in moderate to severe cases of allergic conjunctivitis with immfast check J1 in the spring.
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Amano S.
  • Journal Title: Cornea in press.
  • Peer Reviewed
• [Presentation] 涙液中総IgE抗体価とアレルギー性結膜炎重症度の関係 (2011)
  • Author(s): 保手濱充啓、三村達哉、森樹郎、臼井智彦、天野史郎
  • Organizer: 角膜カンファランス2011第35回日本角膜学会総会第27回日本角膜移植学会
  • Place of Presentation: 東京
  • Year and Date: 2011-02-17
• [Presentation] 秋季アレルギー性結膜炎患者における涙液中特異的IgE (2011)
  • Author(s): 三村達哉、森樹郎、臼井智彦、天野史郎
  • Organizer: 角膜カンファランス2011第35回日本角膜学会総会第27回日本角膜移植学会
  • Place of Presentation: 東京
  • Year and Date: 2011-02-17
• [Presentation] 秋季アレルギー性結膜炎患者における涙液中特異的IgE (2011)
  • Author(s): 三村達哉、森樹郎、臼井智彦、天野史郎
  • Organizer: 角膜カンファランス2011第35回日本角膜学会総会第27回日本角膜移植学会
  • Place of Presentation: 品川
  • Year and Date: 2011-02-17
• [Presentation] 涙液中総IgE抗体価とアレルギー性結膜炎重症度の関係 (2011)
  • Author(s): 保手濱充啓、三村達哉、森樹郎、臼井智彦、天野史郎
  • Organizer: 角膜カンファランス2011第35回日本角膜学会総会第27回日本角膜移植学会
  • Place of Presentation: 品川
  • Year and Date: 2011-02-17
• [Presentation] Role of MT1-MMP (MMP14) on anti-angiogenic proteoglycan, Decorin, in corneal angiogenesis. (2010)
  • Author(s): Tatsuya Mimura
  • Organizer: 16th Kyoto Cornea Club
  • Place of Presentation: 京都
  • Year and Date: 2010-12-03
• [Presentation] Role of MT1-MMP (MMP14) on anti-angiogenic proteoglycan, Decorin, in corneal angiogenesis (2010)
  • Author(s): Tatsuya Mimura
  • Organizer: 16th Kyoto Cornea Club
  • Place of Presentation: 京都
  • Year and Date: 2010-12-03
• [Presentation] 外来でできる涙液・アレルギー検査 (2010)
  • Author(s): 三村達哉
  • Organizer: 第1回虎門会
  • Place of Presentation: 東京
  • Year and Date: 2010-11-24
• [Presentation] 外来でできる涙液・アレルギー検査 (2010)
  • Author(s): 三村達哉
  • Organizer: 第1回 虎門会
  • Place of Presentation: 東京
  • Year and Date: 2010-11-24
• [Presentation] 多種抗原測定キットを用いたアレルギー性結膜炎患者涙液中の特異的IgE (2010)
  • Author(s): 三村達哉
  • Organizer: 第64回日本臨床眼科学会・専門別研究会オキュラーサーフェス研究会
  • Place of Presentation: 神戸
  • Year and Date: 2010-11-11
• [Presentation] アマンタジン内服による両眼性・可逆性角膜浮腫の1症例 (2010)
  • Author(s): 保手濱充啓、三村達哉、臼井智彦、天野史郎、川島秀俊
  • Organizer: 第64回日本臨床眼科学会
  • Place of Presentation: 神戸
  • Year and Date: 2010-11-11
• [Presentation] Rapid measurement of specific tear IgE in allergic conjunctivitis using immfast check J1 in spring. (2010)
  • Author(s): Tatsuya Mimural, Tomohiko Usui, Mikiro Mori, Hideharu Funatsu, Hidetaka Noma, Shiro Amano.
  • Organizer: The Assosiation for Research in Vision and Ophthalmology
  • Place of Presentation: Fort Lauderdale, Florida, USA
  • Year and Date: 2010-05-02
• [Presentation] Rapid measurement of specific tear IgE in allergic conjunctivitis using immfast check J1 in spring (2010)
  • Author(s): Tatsuya Mimura1, Tomohiko Usui, Mikiro Mori, Hideharu Funatsu, Hidetaka Noma, Shiro Amano.
  • Organizer: The Association for Research in Vision and Ophthalmology
  • Place of Presentation: Fort Lauderdale, Florida, USA
  • Year and Date: 2010-05-02
• [Presentation] 網膜静脈閉塞症に伴う黄斑浮腫と細胞接着因子との関連性 (2010)
  • Author(s): 野間英孝、船津英陽、針野正誉、三村達哉、堀貞夫
  • Organizer: 第114回日本眼科学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2010-04-15
• [Presentation] アレルギー性結膜炎患者における血清IgE抗体価と屈折の関係 (2010)
  • Author(s): 三村達哉、森樹郎、臼井智彦、天野史郎
  • Organizer: 第114回日本眼科学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2010-04-15
• [Presentation] 結膜弛緩症と屈折 (2010)
  • Author(s): 豊野哲也、三村達哉、臼井智彦、天野史郎
  • Organizer: 第34回角膜カンファランス第26回日本角膜移植学会
  • Place of Presentation: 宮城県仙台市
  • Year and Date: 2010-02-11
• [Presentation] 結膜弛緩症と屈折 (2010)
  • Author(s): 豊野哲也、三村達哉、臼井智彦、天野史郎
  • Organizer: 第34回角膜カンファランス第26回日本角膜移植学会
  • Place of Presentation: 仙台国際センター
  • Year and Date: 2010-02-11
• [Presentation] 前眼部OCTを用いた全層角膜移植術後内皮面の観察 (2010)
  • Author(s): 福田玲奈、臼井智彦、三村達哉、富所敦男、天野史郎
  • Organizer: 第33回日本眼科手術学会総会
  • Place of Presentation: 東京
  • Year and Date: 2010-01-22
• [Presentation] 多種抗原測定キットを用いたアレルギー性結膜炎患者涙液中の特異的IgE (2009)
  • Author(s): 三村達哉、臼井智彦、本田紀彦、天野史郎
  • Organizer: 第63回日本臨床眼科学会
  • Place of Presentation: 福岡
  • Year and Date: 2009-10-09
• [Presentation] アレルウォッチ涙液中総IgEと血清中総IgEおよび特異的IgEとの相関 (2009)
  • Author(s): 山本裕樹、三村達哉、臼井智彦、本田紀彦、天野史郎
  • Organizer: 第63回日本臨床眼科学会
  • Place of Presentation: 福岡
  • Year and Date: 2009-10-09
• [Presentation] アレルウォッチを用いた涙液、唾液、鼻汁中の総IgE測定 (2009)
  • Author(s): 愛新覚羅維、三村達哉、臼井智彦、本田紀彦、天野史郎
  • Organizer: 第63回日本臨床眼科学会
  • Place of Presentation: 福岡
  • Year and Date: 2009-10-09
• [Presentation] 瞼裂斑の重症度分類 (2009)
  • Author(s): 竇一博、三村達哉、臼井智彦、本田紀彦、山本裕樹、天野史郎、小幡博人
  • Organizer: 第63回日本臨床眼科学会
  • Place of Presentation: 福岡
  • Year and Date: 2009-10-09
• [Presentation] Transplantation of Corneal Stroma Reconstructed with Gelatin and Multipotent Precursor Cells from Human Corneal Stroma. (2009)
  • Author(s): Tatsuya Mimura, Shiro Amano, Tomohiko Usui, Seiichi Yokoo, Satoru Yamagami, Yu Kimura, Yasuhiko Tabata.
  • Organizer: TERMIS国際再生医療学会
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2009-08-31
• [Presentation] Transplantation of Corneal Stroma Reconstructed with Gelatin and Multipotent Precursor Cells from Human Corneal Stroma (2009)
  • Author(s): Tatsuya Mimura, Shiro Amano, Thmohiko Usui, Seiichi Yokoo, Satoru Yamagami, Yu Kimura, Yasuhiko Tabata
  • Organizer: TERMIS 国際再生医療学
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2009-08-31
• [Presentation] 網膜中心静脈分枝閉塞症に伴う黄斑浮腫における前房水と硝子体サイトカイン濃度との関連性 (2009)
  • Author(s): 野間英孝、船津英陽、張野正誉、三村達哉、武田晴信、堀貞夫
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] in vivoでのMT1-MMPのDecorin分解による角膜血管新生誘導 (2009)
  • Author(s): 三村達哉、Chang JH、小島隆司、御宮知達也、崎元暢、臼井智彦、天野史郎、Azar DT.
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] 結膜下出血の原因および部位 (2009)
  • Author(s): 堀田浩史、三村達哉、臼井智彦、本田紀彦、福岡詩麻、天野史郎
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] ヒト角膜輪部上皮前駆細胞の分化能の検討 (2009)
  • Author(s): 横尾誠一、臼井智彦、三村達哉、杉崎顕史、天野史郎、山上聡
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] 培養ヒト角膜内皮細胞を用いたウサギのDescemet stripping endothelial keratoplasty (2009)
  • Author(s): 本田紀彦、三村達哉、臼井智彦、天野史郎、新家眞
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] コンタクトレンズと結膜弛緩 (2009)
  • Author(s): 山本裕樹、三村達哉、臼井智彦、本田紀彦、福岡詩麻、天野史郎
  • Organizer: 第113回日本眼科学会総
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] 線維柱帯切除術前後の波面収差解析の比較 (2009)
  • Author(s): 福岡詩麻、三村達哉、本田紀彦、臼井智彦、天野史郎、新家眞
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] コンタクトレンズと結膜弛緩症(Conjunctivochalasis:CCh) (2009)
  • Author(s): 山本裕樹、三村達哉、臼井智彦、本田紀彦、福岡詩麻、天野史郎
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] 培養ヒト角膜内皮細胞を用いたウサギの Descemet stripping endothelial keratoplasty (2009)
  • Author(s): 本田紀彦、三村達哉、臼井智彦、天野史郎、新家眞
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] in vivo でのMT1-MMPの Decorin 分解による角膜血管新生誘導 (2009)
  • Author(s): 三村達哉、Chang Jin-Hong、小島隆司、御宮知達也、崎元暢、臼井智彦、天野史郎、Dimitri T.Azar
  • Organizer: 第113回日本眼科学会総会
  • Place of Presentation: 東京
  • Year and Date: 2009-04-16
• [Presentation] コンタクトレンズと瞼裂斑 (2009)
  • Author(s): 山本裕樹、三村達哉、臼井智彦、本田紀彦、福岡詩麻、天野史郎
  • Organizer: 第33回角膜カンファランス第25回日本角膜移植学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-19
• [Presentation] 近年の結膜下出血の原因および発症時期 (2009)
  • Author(s): 堀田浩史、三村達哉、臼井智彦、本田紀彦、福岡詩麻、天野史郎
  • Organizer: 第33回角膜カンファランス第25回日本角膜移植学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-19
• [Presentation] 結膜下出血と結膜弛緩症 (2009)
  • Author(s): 白川理香、三村達哉、臼井智彦、本田紀彦、福岡詩麻、天野史郎
  • Organizer: 第33回角膜カンファランス第25回日本角膜移植学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-19
• [Presentation] マウス角膜血管新生モデルにおけるアンジオポエチン様因子2の発現 (2009)
  • Author(s): 臼井智彦、本田紀彦、横尾誠一、三村達哉、天野史郎、尾池雄一
  • Organizer: 第33回角膜カンファランス第25回日本角膜移植学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-19
• [Presentation] Azar角膜血管新生におけるin vitroでのMT1-MMPのDecorin分解 (2009)
  • Author(s): 三村達哉、Jin-Hong Chang、小島隆司、御宮知達也、崎元暢、臼井智彦、天野史郎、Dimitri T.
  • Organizer: 第33回角膜カンファランス第25回日本角膜移植学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-19
• [Presentation] 培養ヒト角膜内皮細胞を用いたDescemet stripping endothelial keratoplastyグラフト (2009)
  • Author(s): 本田紀彦、三村達哉、臼井智彦、新家眞、天野史郎
  • Organizer: 第33回角膜カンファランス第25回日本角膜移植学会
  • Place of Presentation: 大阪
  • Year and Date: 2009-02-19
• [Presentation] 春季カタル患者の涙液中におけるVEGF濃度 (2008)
  • Author(s): 臼井智彦、三村達哉、本田紀彦、山上聡、天野史郎
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] 結膜弛緩症重症度の年齢および部位による比較 (2008)
  • Author(s): 三村達哉、臼井智彦、小野恭子、本田紀彦、福岡詩麻、山上聡、天野史郎
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] 網膜静脈分枝閉塞症に伴う黄斑浮腫とサイトカインとの関係 (2008)
  • Author(s): 野間英孝、船津英陽、張野正誉、三村達哉、武田晴信、堀貞夫
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] 眼窩内に発症したLymphomatoid granulomatosisの1例 (2008)
  • Author(s): 山本裕樹、三村達哉、荒木章之、福岡詩麻、臼井智彦、天野史郎、辻英貴、伊豆津宏二、高澤豊、小島孚允
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] 好酸球増多症の経過中に発症したIgG4関連ミクリッツ病の1例 (2008)
  • Author(s): 玉島順子、臼井智彦、大道幸子、三村達哉、天野史郎、辻英貴
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] ラタノプロスト点眼液使用患者の眼表面MMPsの発現変化 (2008)
  • Author(s): 本田紀彦、臼井智彦、三村達哉、小島良平、宮井尊史、宮田和典、天野史郎
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] コンフォーカルスキャンによる羊膜被覆角膜の観察 (2008)
  • Author(s): 堀田浩史、三村達哉、臼井智彦、本田紀彦、福岡詩麻、荒木章之、山上聡、天野史郎
  • Organizer: 第62回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2008-10-23
• [Presentation] (2008)
  • Organizer: ARVO 2008
  • Place of Presentation: フロリダアメリカ合衆国
  • Year and Date: 2008-05-01
• [Presentation] Cell Sheet Using Cultured Human Corneal Endothelial Cell Precursors. (2008)
  • Author(s): Tatsuya Mimura, Shiro Amano, Tomohiko Usui, Norihiko Honda, Seiichi Yokoo, Satoru Yamagami.
  • Organizer: The Assosiation for Research in Vision and Ophthalmology
  • Place of Presentation: Fort Lauderdale, Florida, USA
  • Year and Date: 2008-04-27
• [Presentation] ヒト角膜内皮細胞の増殖能および老化の中央部と周辺部における比較 (2008)
  • Author(s): 三村達哉、許斐健二、榎本喜久子、石野豊、天野史郎、山上聡、臼井智彦、Joyce Nancy C.
  • Organizer: 第112回日本眼科学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-17
• [Presentation] 起立性低血圧に伴って一過性黒内障を繰り返した糖尿病網膜症 (2008)
  • Author(s): 武田晴信、三村達哉、重枝崇志、天野史郎、加藤聡、野間英孝、船津英陽、北野滋彦、堀貞夫
  • Organizer: 第112回日本眼科学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-17
• [Presentation] 網膜中心静脈分枝閉塞症に伴う黄斑浮腫とサイトカインとの関連性 (2008)
  • Author(s): 野間英孝、船津英陽、張野正誉、三村達哉、武田晴信、堀貞夫
  • Organizer: 第112回日本眼科学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-17
• [Presentation] 先天性無痛汗症患者の角膜異常 (2008)
  • Author(s): 福岡詩麻、三村達哉、有田玲子、本田紀彦、柳澤美衣子、落合真紀子、荒木章之、臼井智彦、山上聡、新家眞、天野史郎、粟屋豊
  • Organizer: 第112回日本眼科学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2008-04-17
• [Book] Current Concepts, Classification and History of Refractive Surgery. Yanoff & Duker Ophthaln (2008)
  • Author(s): Mimura T,Azar DT.
  • Publisher: Mosby