| Project/Area Number |
20700266
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
OGISHIMA Soichi Tokyo Medical and Dental University, 難治疾患研究所, 助教 (40447496)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | システム生物 / システム進化 / 初期胚発生 / Hox / 生命情報学 |
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| Research Abstract |
We identified Hox transcriptional networks which have key roles in regulating the patterning of the antero-posterior axis at phylotypic stage in a metazoan embryo. We conducted bioinformatics methods including promoter analysis on Hox regulating genes in each evolutionary stage and anatomical structure which were retrieved from public gene expression database. We then compared Hox transcriptional networks among mouse, sea squirt, and fruit fly.
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