Development of a DNA computing mechanism that is controlled through optical input

• Project/Area Number: 20700276
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Bioinformatics/Life informatics
• Research Institution: Osaka University
• Principal Investigator: OGURA Yusuke Osaka University, 大学院・情報科学研究科, 准教授 (20346191)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: DNAコンピュータ / 光DNA演算 / 光信号 / ヘアピンDNA / 液滴 / 光DNA操作ユニット / アゾベンゼン

Research Abstract

We designed a photonically-controlled DNA reaction system and verified its basic behavior to realize nanoscale computing. Local execution of DNA logic operations by optical manipulation of micro-droplets was also demonstrated.

Research Products

• [Journal Article] Implementation of a Nanoscale Automaton Using DNA Conformation Controlled by Optical Signals (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Journal Title: Japanese Journal of Applied Physics 48
  • NAID: 210000067478
  • Peer Reviewed
• [Journal Article] Positional State Representation and Its Transition Control for Photonic DNA Automaton (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Journal Title: Lecture Notes in Computer Science 5877 Pages: 126-136
  • Peer Reviewed
• [Journal Article] Self-Contained Photonically-Controlled DNA Tweezers (2009)
  • Author(s): Yusuke Ogura, Takahiro Nishimura, Jun Tanida
  • Journal Title: Applied Physics Express 2 Pages: 25004-25004
  • NAID: 10025084797
  • Peer Reviewed
• [Journal Article] Implementation of a Nanoscale Automaton Using DNA Conformation Controlled by Optical Signals (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Journal Title: Japanese Journal of Applied Physics VOL.48
  • NAID: 210000067478
  • Peer Reviewed
• [Journal Article] Positional State Representation and Its Transition Control for Photonic DNA Automaton (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Journal Title: Lecture Notes in Computer Science VOL.5877 Pages: 126-136
  • Peer Reviewed
• [Journal Article] Self-Contained Photonically-Controlled DNA Tweezers (2009)
  • Author(s): Yusuke Ogura, Takahiro Nishimura, and Jun Tanida
  • Journal Title: Applied Physics Express 2 Pages: 25004-25004
  • NAID: 10025084797
  • Peer Reviewed
• [Presentation] DNA構造を用いた光入力2進カウンタ (2010)
  • Author(s): 酒井寛人, 小倉裕介, 谷田純
  • Organizer: 2010年春季第57回応用物理学関係連合講演会
  • Place of Presentation: 東海大学(神奈川県)
  • Year and Date: 2010-03-18
• [Presentation] 微小液滴の光操作に基づく局所的DNA論理演算 (2010)
  • Author(s): 西村隆宏, 小倉裕介, 谷田純
  • Organizer: 2010年春季第57回応用物理学関係連合講演会
  • Place of Presentation: 東海大学
  • Year and Date: 2010-03-17
• [Presentation] 微小液滴の光操作に基づく局所的DNA論理演算 (2010)
  • Author(s): 西村隆宏, 小倉裕介, 谷田純
  • Organizer: 2010年春季第57回応用物理学関係連合講演会
  • Place of Presentation: 東海大学(神奈川県)
  • Year and Date: 2010-03-17
• [Presentation] 空間光変調器を用いた液滴操作に基づく空間並列DNA演算 (2010)
  • Author(s): 小倉裕介, 西村隆宏, 谷田純
  • Organizer: レーザー学会学術講演会第30回年次大会
  • Place of Presentation: 千里ライフサイエンスセンター
  • Year and Date: 2010-02-04
• [Presentation] 空間光変調器を用いた液滴操作に基づく空間並列DNA演算 (2010)
  • Author(s): 小倉裕介, 西村隆宏, 谷田純
  • Organizer: レーザー学会学術講演会第30回年次大会
  • Place of Presentation: 千里ライフサイエンスセンター(大阪府)
  • Year and Date: 2010-02-04
• [Presentation] ナノ定規:DNA構造と蛍光共鳴エネルギー移動(FRET)を用いたナノ距離情報取得 (2009)
  • Author(s): 酒井寛人, 小倉裕介, 谷田純
  • Organizer: Optics & Photonics Japan 2009
  • Place of Presentation: 朱鷺メッセ:新潟コンベンションセンター(新潟県)
  • Year and Date: 2009-11-24
• [Presentation] Photonic Switching of DNA's Position That Represents the Internal State in Photonic DNA Automaton (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Organizer: 4th International Workshop on Natural Computing
  • Place of Presentation: Hyogo, Japan
  • Year and Date: 2009-09-23
• [Presentation] Photonic Switching of DNA's Position That Represents the Internal State in Photonic DNA Automaton (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Organizer: 4th International Workshop on Natural Computing (IWNC 2009)
  • Place of Presentation: Himeji International Exchange Center (Hyogo, Japan)
  • Year and Date: 2009-09-23
• [Presentation] 光学的手法に基づくDNAの位置・局所反応の並列制御 (2009)
  • Author(s): 西村隆宏, 小倉裕介, 谷田純
  • Organizer: 2009年秋季第70回応用物理学会学術講演会
  • Place of Presentation: 富山大学
  • Year and Date: 2009-09-11
• [Presentation] 光学的手法に基づくDNAの位置・局所反応の並列制御 (2009)
  • Author(s): 西村隆宏, 小倉裕介, 谷田純
  • Organizer: 2009年秋季第70回応用物理学会学術講演会講演予稿集
  • Place of Presentation: 富山大学(富山県)
  • Year and Date: 2009-09-11
• [Presentation] A Nanoscale Ruler by Use of Fluorescence Resonance Energy Transfer and DNA Nano-Structure (2009)
  • Author(s): Yusuke Ogura, Yuta Fukushima, Hiroto Sakai, Jun Tanida
  • Organizer: CLEO/Pacific Rim 2009
  • Place of Presentation: Shanghai International Convention Center (Shanghai, China)
  • Year and Date: 2009-09-02
• [Presentation] Enhancing the Performance of Photonic DNA Nanomachines for Implementing Photonic Nanoscale Automaton (2009)
  • Author(s): Takahiro Nishimura, Yusuke Ogura, Jun Tanida
  • Organizer: SPIE Optics & Photonics 2009
  • Place of Presentation: San Diego, USA
  • Year and Date: 2009-08-04
• [Presentation] Enhancing the Performance of Photonic DNA Nanomachines for Implementing Photonic Nanoscale Automaton (2009)
  • Author(s): Takahiro Nishimura, Yusuke Ogura, Jun Tanida
  • Organizer: SPIE Optics & Photonics 2009
  • Place of Presentation: San Diego Convention Center (San Diego, USA)
  • Year and Date: 2009-08-04
• [Presentation] Positional State Representation and Its Transition Control for Photonic DNA Automaton (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Organizer: 15th International Meeting on DNA Computing and Molecular Programming
  • Place of Presentation: Arkansas, USA
  • Year and Date: 2009-06-09
• [Presentation] Positional State Representation and Its Transition Control for Photonic DNA Automaton (2009)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Organizer: 15th International Meeting on DNA Computing and Molecular Programming
  • Place of Presentation: University of Arkansas (Arkansas, USA)
  • Year and Date: 2009-06-09
• [Presentation] フォトニックDNAオートマトン:概念と実装法 (2009)
  • Author(s): 小倉裕介, 酒井寛人, 谷田純
  • Organizer: レーザー学会学術講演会第29回年次大会
  • Place of Presentation: 徳島大学
  • Year and Date: 2009-01-10
• [Presentation] フォトニックDNAオートマトン : 概念と実装法 (2009)
  • Author(s): 小倉裕介, 酒井寛人, 谷田純
  • Organizer: レーザー学会学術講演会第29回年次大会
  • Place of Presentation: 徳島大学
  • Year and Date: 2009-01-10
• [Presentation] An Implementation of a Nanoscale Automaton Using DNA Conformation Controlled by Optics Signals (2008)
  • Author(s): Hiroto Sakai, Yusuke Ogura, Jun Tanida
  • Organizer: International Topical Meeting on Information Photonics 2008
  • Place of Presentation: Hyogo, Japan
  • Year and Date: 2008-11-19
• [Presentation] Concept and Primal Implementation of Photonic Nanoscale Automaton (2008)
  • Author(s): Yusuke Ogura, Takahiro Nishimura, Yuichiro Horiguchi, Jun Tanida
  • Organizer: International Topical Meeting on Information Photonics 2008
  • Place of Presentation: Hyogo, Japan
  • Year and Date: 2008-11-17
• [Presentation] 光信号による自己完結型DNAナノマシンの状態遷移制御 (2008)
  • Author(s): 西村隆宏, 小倉裕介, 谷田純
  • Organizer: Optics & Photonics Japan 2008
  • Place of Presentation: つくば国際会議場
  • Year and Date: 2008-11-05
• [Presentation] Large-Area Manipulation of DNA Clusters for Photonics DNA Computing (2008)
  • Author(s): Yusuke Ogura, Mingjie Zheng, and Jun Tanida
  • Organizer: Topical Meeting on Optoinformatics '08
  • Place of Presentation: St. Petersburg, Russia
  • Year and Date: 2008-09-16
• [Presentation] 光入力型ナノスケールオートマトンのための光信号によるDNA構造制御 (2008)
  • Author(s): 酒井寛人, 小倉裕介, 谷田純
  • Organizer: 2008年秋季第69回応用物理学会学術講演会
  • Place of Presentation: 中部大学
  • Year and Date: 2008-09-04
• [Presentation] State-Transition of DNA Nanomachines Based on Photonic Control (2008)
  • Author(s): Yusuke Ogura, Takahiro Nishimura, and Jun Tanida
  • Organizer: SPIE Optics + Photonics 2008
  • Place of Presentation: San Diego, CA, USA
  • Year and Date: 2008-08-13
• [Presentation] Stepwise State-Transition of DNA Structures Controlled Through Sequential Photonic Signals (2008)
  • Author(s): Yusuke Ogura, Yuichiro Horiguchi, and Jun Tanida
  • Organizer: 14th International Meeting on DNA Computing
  • Place of Presentation: Prague, Czech Republic
  • Year and Date: 2008-06-04
• [Remarks]
  • URL: http://www-lip.ist.osaka-u.ac.jp/research/index.html
• [Remarks]
  • URL: http://www-lip.ist.osaka-u.ac.jp/research/index.html