Migratory pathway and mode of inhibitory neurons within the marmoset cerebral corte

• Project/Area Number: 20700288
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Neuroscience in general
• Research Institution: Keio University
• Principal Investigator: TANAKA Daisuke Keio University, 医学部, 助教 (90456921)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
• Keywords: 発生 / 発達 / 再生神経科学 / マーモセット / 大脳皮質 / 抑制性神経細胞 / 細胞移動 / GABA / 移植

Research Abstract

I examined the migratory pathways and modes of inhibitory neurons within the developing marmoset (monkey) cerebral cortex and differences between the marmoset and mouse (rodent) in terms of their migratory pathways, modes and motility. I found that migratory pathway and mode were similar between marmoset and mouse, but marmoset cells showed higher motility compared to mouse cells.

Research Products

• [Presentation] Migratory pathways of avian MGE-derived GABAergic interneurons in the mammalian neocortex: implications for the evolutional adaptation in GABAergic interneuron migration (2009)
  • Author(s): Tanaka DH, Nakajima K.
  • Organizer: Construction and Reconstruction of the Brain.
  • Place of Presentation: Awaji, Japan
• [Presentation] Behavior of avian pallial GABAergic interneurons in the mammalian neocortex: implications for the evolutional adaptation to the neocortex in pallial GABAergic interneurons (2009)
  • Author(s): Tanaka DH, Nakajima K.
  • Organizer: The 32th Annual Meeting of the Japan Neuroscience Society.
  • Place of Presentation: Nagoya, Japan