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Analysis of mouse higher-order visual cortex by differential imaging

Research Project

Project/Area Number 20700347
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionNiigata University

Principal Investigator

TOHMI Manavu  Niigata University, 脳研究所, 助教 (10401770)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords高次視覚領域 / フラビン蛍光イメージング / 差分イメージング / 経験依存的可塑性 / in vivo / プロトカドヘリン / ノックアウトマウス / スライス
Research Abstract

It became possible to separate and to identify mouse's several higher-order visual areas by the combination with the pattern stimulus having different speed with flavin fluorescent imaging. Therefore the high order visual areas which were difficult to study until that time were observed. The properties of neurons in each area were different in the directional selectivity and the preferred stimulation speed. The property was disturbed in the animal that had bred under the flash light condition. Moreover, the anatomical combinations of each region were observed using with neural traser. Finally, abnormality was discovered in the property of the higher-order visual areas in the knockout mouse of cell-adhesion molecule CNR.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (11 results)

All 2009 2008 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (7 results) Book (2 results)

  • [Journal Article] Transcranial flavoprotein fluorescence imaging of mouse cortical activity and plasticity2009

    • Author(s)
      M. Tohmi, K. Takahashi, Y. Kubota, R. Hishida, K. Shibuki
    • Journal Title

      Journal of Neurochemistry 第109巻

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial flavoprotein fluorescence imaging of mouse cortical activity and plasticity

    • Author(s)
      M.Tohmi, K.Takahashi, Y.Kubota, R.Hishida, K.Shibuki
    • Journal Title

      Journal of Neurochemistry (In Press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Imaging of higher visual cortices based on differences in response properties between the primary and higher visual cortices in mice2009

    • Author(s)
      M. Tohmi
    • Organizer
      38th annual meeting of the Society for Neuroscience
    • Place of Presentation
      アメリカ合衆国シカゴ
    • Year and Date
      2009-10-19
    • Related Report
      2009 Final Research Report
  • [Presentation] Imaging of higher visual cortices based on differences in response properties between the primary and higher visual cortices in mice2009

    • Author(s)
      M Tohmi, R Meguro, R Hishida, M Norita, T Yagi, K Shibuki
    • Organizer
      38th annual meeting of the Society for Neuroscience
    • Place of Presentation
      シカゴ
    • Year and Date
      2009-10-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] Imaging of higher visual cortices based on differences in response properties between the primary and higher visual cortices in mice2009

    • Author(s)
      M. Tohmi
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Imaging of higher visual cortices based on differences in response properties between the primary and higher visual cortices in mice2009

    • Author(s)
      M. Tohmi
    • Organizer
      The 36th IUSP2009 Congress
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2009-07-30
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Autofluorescence imaging revealed the property and the plasticity of the mouse high order visual cortex2008

    • Author(s)
      M. Tohmi
    • Organizer
      38th annual meeting of the Society for Neuroscience
    • Place of Presentation
      アメリカ合衆国ワシントン. D.C.
    • Year and Date
      2008-11-16
    • Related Report
      2009 Final Research Report
  • [Presentation] The Autofluorescence imaging revealed the property and the plasticity of the mouse high order visual cortex2008

    • Author(s)
      M. Tohmi
    • Organizer
      38th annual meeting of the Society for Neuroscience
    • Place of Presentation
      ワシントン. D.C
    • Year and Date
      2008-11-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] The Autofluorescence imaging revealed the property and the plasticity of the mouse high order visual cortex2008

    • Author(s)
      任海学
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-07-10
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Book] In In vivo optical imaging of brain function 2nd Edition2009

    • Author(s)
      K. Shibuki, R. Hishida, M. Tohmi, K. Takahashi, H. Kitaura, Y. Kubota
    • Total Pages
      28
    • Publisher
      Frostig Red
    • Related Report
      2009 Final Research Report
  • [Book] In In vivo optical imaging of brain function 2nd Edition2009

    • Author(s)
      K. Shibuki, R. Hishida, M. Tohmi, K. Ta kahashi, H. Kitaura, Y. Kubota
    • Publisher
      Frostig R ed(印刷中)
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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