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Memory formation based on reward in inferior temporal cortex

Research Project

Project/Area Number 20700356
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

SUGASE Yasuko  National Institute of Advanced Industrial Science and Technology, ヒューマンライフテクノロジー研究部門, 主任研究員 (40357257)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords認知 / 言語 / 記憶 / 情動 / 学習 / 連合学習 / 下側頭皮質
Research Abstract

To investigate neuronal processing in perirhinal cortex during stimulus-stimulus-reward associations, we recorded single unit data from neurons in the perirhinal cortex using two monkeys performing bar-release response trials imbedded within a delayed conditioning paradigm. The neurons in the perirhinal cortex have signals about stimulus identity, predicted reward contingency, and memory for a preceding stimulus. The pattern cue elicited responses during the conditional association task were not simply related to physical stimulus characteristics. These results showed that most of the neurons had activity distinguishing the conditional association task, suggesting an important role of perirhinal cortex when stimulus-stimulus sequences lead to different reward outcomes.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (6 results)

All 2009 2008

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (5 results)

  • [Journal Article] Short-Term Memory Trace in Rapidly Adapting Synapses of Inferior Temporal Cortex.2008

    • Author(s)
      Sugase-Miyamoto Y. et al.
    • Journal Title

      PLoS computational biology 4

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Encoding of stimulus-stimulus association and reward contingency in monkey perirhinal cortex during conditional association task2009

    • Author(s)
      内山薫、松本有央、設樂宗孝、菅生康子
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-19
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Encoding of visual stimulus, memroy and reward expectation in monkey perirhinal cortex during delayed conditioning2009

    • Author(s)
      内山薫、松本有央、設樂宗孝、菅生康子
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋,愛知
    • Year and Date
      2009-09-18
    • Related Report
      2009 Final Research Report
  • [Presentation] Encoding of visual stimulus, memory and reward expectation in monkey perirhinal cortex during delayed conditioning2009

    • Author(s)
      内山薫、松本有央、設楽宗孝、菅生康子
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋、愛知
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Visual, memory and reward expectation signals in monkey perirhinal cortex during delayed conditioning2008

    • Author(s)
      内山薫、松本有央、設樂宗孝、Richmond BJ(NIMH, NIH)、菅生康子
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-16
    • Related Report
      2009 Final Research Report
  • [Presentation] Experience-dependent stimulus-reward/non-reward association during delayed conditioning2008

    • Author(s)
      内山薫、松本有央、設樂宗孝、菅生康子
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-10
    • Related Report
      2009 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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