• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Establishment of noninvasive neuroimaging analysis in experimental animals by using diffusion weighted magnetic resonance imaging.

Research Project

Project/Area Number 20700371
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Laboratory animal science
Research InstitutionFujita Health University

Principal Investigator

YAMADA Masayuki  Fujita Health University, 医療科学部, 准教授 (40383773)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords動物実験技術 / MRI / 拡散 / 実験動物 / 拡散テンソル / 神経変性 / 脳・神経 / 磁気共鳴画像法(MRI) / 神経画像解析
Research Abstract

The purpose of this study was to establish a noninvasive imaging analysis for detecting neural degeneration in the experimental animals by using magnetic resonance (MR) imaging. In this study, manganese enhanced MR imaging was optimized as a tool to depict the normal neural pathways in non-human primates in vivo. Furthermore, diffusion tensor MR imaging was performed to detect the degeneration on the retinal projection pathways of the animals. Results of this study suggest that diffusion weighted MR imaging is a useful tool for noninvasive neuroimaging analysis in the experimental animals.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (8 results)

All 2009 2008

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results)

  • [Journal Article] マンガン神経トレーシング法(MEMRI tract-tracing)による霊長類視覚伝導路の描出と網膜神経分布の解析2009

    • Author(s)
      山田雅之, 疋島啓吾, 藤吉兼浩, 他
    • Journal Title

      日本磁気共鳴医学会雑誌 29巻1号

      Pages: 23-29

    • NAID

      10026287370

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] マンガン神経トレーシング法 (MEMRI tract-tracing) による霊長類視覚伝導路の描出と網膜神経分布の解析2009

    • Author(s)
      山田雅之、疋島啓吾, 他
    • Journal Title

      日本磁気共鳴医学会雑誌 29

      Pages: 23-29

    • NAID

      10026287370

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diffusion-tensor neuronal fiber tractography and manganese-enhanced MR imaging of primate visual pathway in the common marmoset: preliminary results.2008

    • Author(s)
      M. Yamada, S. Momoshima, Y., Y. Masutani, et. al.
    • Journal Title

      Radiology 249(3)

      Pages: 855-64

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] 拡散テンソルMRIの解析から得られる各種異方性インデックスを用いた変性神経組織の病態検出に関する検討2009

    • Author(s)
      山田雅之, 他
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      横浜市
    • Year and Date
      2009-10-02
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 基礎医学研究におけるMRIの応用-神経路画像解析法の有用性2009

    • Author(s)
      山田雅之
    • Organizer
      第9回東京臨床脳画像解析研究会
    • Place of Presentation
      東京都
    • Year and Date
      2009-06-13
    • Related Report
      2009 Final Research Report
  • [Presentation] 基礎医学研究におけるMRIの応用-神経路画像解析法の有用性-2009

    • Author(s)
      山田雅之
    • Organizer
      第9回東京臨床脳画像解析研究会
    • Place of Presentation
      東京都
    • Year and Date
      2009-06-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] マンガン神経トレーシング法(MEMRI tract-tracing)による霊長類視覚伝導路の描出と網膜神経分布の解析2008

    • Author(s)
      山田雅之, 他
    • Organizer
      第36回日本磁気共鳴医学会大会
    • Place of Presentation
      旭川市
    • Year and Date
      2008-09-12
    • Related Report
      2009 Final Research Report
  • [Presentation] マンガン神経トレーシング法(MEMRI tract-tracing)による霊長類視覚伝導路の描出と網膜神経分布の解析2008

    • Author(s)
      山田雅之、疋島啓吾, 他
    • Organizer
      第36回日本磁気共鳴医学会大会
    • Place of Presentation
      旭川・北海道
    • Year and Date
      2008-09-12
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi