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Development of computational biomechanics of gastric mixing

Research Project

Project/Area Number 20700373
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionTohoku University

Principal Investigator

IMAI Yohsuke  Tohoku University, 大学院・工学研究科, 助教 (60431524)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords消化器 / 食塊攪拌 / バイオメカニクス / 生理流体力学 / 計算力学 / 生物・生体工学 / 計算物理 / モデル化 / 流体 / 生理学
Research Abstract

We developed a computational fluid dynamics model of gastric mixing. Moving wall condition of antral contraction wave and free-surface condition of gastric gas were given as boundary conditions of the numerical model. We investigated the effects of physiological conditions such as the viscosity and volume of food bolus and the antral contraction wave pattern on the mixing efficiency and fluid stress in the stomach.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (22 results)

All 2011 2010 2009 2008

All Journal Article (16 results) (of which Peer Reviewed: 16 results) Presentation (6 results)

  • [Journal Article] Patient-specific modelling of pulmonary airflow using GPU cluster for the application in medical practice2011

    • Author(s)
      Miki, T., Wang, X., Aoki, T., Imai, Y., Ishikawa, T., Takase, K., Yamaguchi, T.
    • Journal Title

      Computer Methods in Biomechanics and Biomedical Engineering in press

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A fourth-order Cartesian local mesh refinement method for the computational fluid dynamics of physiological flow in multi-generation branched vessels2011

    • Author(s)
      Miki, T., Imai, Y., Ishikawa, T., Wada, S., Aoki, T., Yamaguchi, T.
    • Journal Title

      International Journal for Numerical Methods in Biomedical Engineering Vo.27

      Pages: 424-435

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Margination of red blood cells infected by Plasmodium falciparum in a microvessel2011

    • Author(s)
      Imai, Y., Nakaaki, K., Kondo, H., Ishikawa, T., Lim, C.T., Yamaguchi, T.
    • Journal Title

      Journal of Biomechanics Vol.44

      Pages: 1553-1558

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A fourth-order Cartesian local mesh refinement method for the computational fluid dynamics of physiological flow in multi-generation branched vessels2011

    • Author(s)
      T.Miki
    • Journal Title

      International Journal for Numerical Methods in Biomedical Engineering

      Volume: (未定 印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Margination of red blood cells infected by Plasmodium falciparum in a microvessel2011

    • Author(s)
      Y.Imai
    • Journal Title

      Journal of Biomechanics

      Volume: (未定 印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modeling of hemodynamics arising from malaria infection2010

    • Author(s)
      Imai, Y., Kondo, H., Ishikawa, T., Lim, C.T., Yamaguchi, T.
    • Journal Title

      Journal of Biomechanics Vol.43

      Pages: 1386-1393

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Particle-based methods for multiscale modeling of blood flow in the circulation and in devices : challenges and future directions2010

    • Author(s)
      Yamaguchi, T., Ishikawa, T., Imai, Y., Matsuki, N., Xenos, M., Dengand, Y., Bluestein, D.
    • Journal Title

      Annals of Biomedical Engineering Vol.38

      Pages: 1225-1235

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] ATP transport in saccular cerebral aneurysms at arterial bends2010

    • Author(s)
      Imai, Y., Sato, K., Ishikawa, T., Comerford, A., David, T., Yamaguchi, T.
    • Journal Title

      Annals of Biomedical Engineering Vol.38

      Pages: 927-934

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modeling of hemodynamics arising from malaria infection2010

    • Author(s)
      Y.Imai
    • Journal Title

      Journal of Biomechanics

      Volume: 43 Pages: 1386-1393

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ATP transport in saccular cerebral aneurysms at arterial bends2010

    • Author(s)
      Y.Imai
    • Journal Title

      Annals of Biomedical Engineering 38

      Pages: 927-924

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Particle-based methods for multiscale modeling of blood flow in the circulation and in devices : challenges and future directions2010

    • Author(s)
      T.Yamaguchi
    • Journal Title

      Annals of Biomedical Engineering 38

      Pages: 1225-1235

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hemodynamic analysis of microcirculation in malaria infection2009

    • Author(s)
      Kondo, H., Imai, Y., Ishikawa, T., Lim, C.T., Yamaguchi, T.
    • Journal Title

      Annals of Biomedical Engineering Vol.37

      Pages: 702-709

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hemodynamic analysis of microcirculation in malaria infection2009

    • Author(s)
      H.Kondo
    • Journal Title

      Annals of Biomedical Engineering 37

      Pages: 702-709

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inflow into saccular cerebral aneurysms at arterial bends2008

    • Author(s)
      Y. Imai
    • Journal Title

      Annals of Biomedical Engineering 36

      Pages: 1489-1495

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional simulation of blood flow in malaria infection2008

    • Author(s)
      Y. Imai
    • Journal Title

      Proceedings of 13th International Conference on Biomedical Engineering

      Pages: 133-133

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A numerical model of blood flow with malaria infected red blood cells2008

    • Author(s)
      Y. Imai
    • Journal Title

      Journal of Biomechanics 41

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 胃内容物攪拌の数値流体力学モデルの開発2011

    • Author(s)
      今井陽介, 小林生馬, 石田駿一, 石川拓司, 山口隆美
    • Organizer
      日本機械学会第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本市
    • Year and Date
      2011-01-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 胃内容物流れの数値シミュレーション:内容物量の影響2010

    • Author(s)
      小林生馬, 今井陽介, 石田駿一, 石川拓司, 山口隆美
    • Organizer
      日本機械学会第21回バイオフロンティア講演会
    • Place of Presentation
      金沢市
    • Year and Date
      2010-11-12
    • Related Report
      2010 Final Research Report
  • [Presentation] A numerical study on fluid motion in the stomach2010

    • Author(s)
      Kobayashi, I., Imai, Y., Ishida, S., Ishikawa, Yamaguchi, T.
    • Organizer
      6th World Congress on Biomechanics
    • Place of Presentation
      Singapore.シンガポール
    • Year and Date
      2010-08-06
    • Related Report
      2010 Final Research Report
  • [Presentation] A numerical study on fluid motion in the stomach2010

    • Author(s)
      I.Kobayashi
    • Organizer
      6th World Congress on Biomechanics
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2010-08-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] 粒子法を用いた胃内容物攪拌の数値シミュレーション2010

    • Author(s)
      小林生馬, 今井陽介, 石田駿一, 石川拓司, 山口隆美
    • Organizer
      日本機械学会東北支部第45期講演会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-03-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 粒子法を用いた胃内容物撹拌の数値シミュレーション2010

    • Author(s)
      小林生馬
    • Organizer
      日本機械学会東北支部 第45期講演会
    • Place of Presentation
      仙台
    • Year and Date
      2010-03-12
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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