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Mechanical effect on bone mineralization and microstructure in cortex

Research Project

Project/Area Number 20700378
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionNiigata University

Principal Investigator

YAMAKO Go  Niigata University, ベンチャー・ビジネス・ラボラトリー, VBL研究機関研究員 (50452074)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords生体力学 / 機械材料・材料力学 / 生体材料
Research Abstract

Osteoporotic femoral neck fracture is associated with the change in bone mechanical properties that are determined by the tissue mineral density and micro-porous structure. To estimate bone fragility by osteoporosis non-invasively, we quantified the tissue mineral density and porous structure in the femoral cortex of patients with total hip arthroplasty, using a polychromatic micro CT system with K2HPO4 phantom. Our results showed that bone mineral density distribution could assume to be homogeneous, and indicated the importance of the porosity on the mechanical properties of cortical bone.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (9 results)

All 2010 2009 2008

All Presentation (9 results)

  • [Presentation] Effect of Bone Quality on the Initial Stability of the Cementless Hip Stem, based on Patient-specific Finite Element Analysis2010

    • Author(s)
      Go Yamako.
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      New Orleans, Louisiana
    • Related Report
      2009 Final Research Report
  • [Presentation] Postoperative Evaluation of the Initial Stability of the Cementless Hip Stem using Patient-specific Finite Element Analysis2010

    • Author(s)
      Go Yamako.
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      New Orleans, Louisiana
    • Related Report
      2009 Final Research Report
  • [Presentation] Effect of Bone Quality on the Initial Stability of the Cementless Hip Stem, based on Patient-specific Finite Element Analysis.2010

    • Author(s)
      Yamako G
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      New Orleans, Louisiana
    • Related Report
      2009 Annual Research Report
  • [Presentation] Postoperative Evaluation of the Initial Stability of the Cementless HipStem using Patient-specific Finite Element Analysis.2010

    • Author(s)
      Yamako G
    • Organizer
      56th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      New Orleans, Louisiana
    • Related Report
      2009 Annual Research Report
  • [Presentation] Accurate Technique for measuring Bone Mineralization using Polychromatic Microcomputed Tomography2009

    • Author(s)
      Go Yamako.
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas, Nevada.
    • Related Report
      2009 Final Research Report
  • [Presentation] A Novel Technique for Precisely Measuring the Three-dimensional Location of Cementless THA Implants using Pre- and Postoperative CT Images2009

    • Author(s)
      Go Yamako.
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas, Nevada.
    • Related Report
      2009 Final Research Report
  • [Presentation] Accurate Technique for measuring Bone Mineralization using Polychromatic Microcomputed Tomography2009

    • Author(s)
      Yamako G
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas, Nevada, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Novel Technique for Precisely Measuring the Three-dimensional Location of Cementless THA Implants using Pre- and Postoperative CT Images2009

    • Author(s)
      Yamako G
    • Organizer
      55th Annual Meeting of the Orthopaedic Research Society
    • Place of Presentation
      Las Vegas, Nevada, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] 術前・術後CT画像に基づく患者別セメントレスステム大腿骨の初期固定性評価2008

    • Author(s)
      山子剛
    • Organizer
      第35回日本臨床バイオメカニクス学会
    • Place of Presentation
      大阪
    • Related Report
      2009 Final Research Report 2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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