| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Research Abstract |
I have analyzed the spatiotemporal patterns of the cell peripheral activity and the shape, and the relation between the patterns of them. The analysis revealed the mechanism determining the cell peripheral activity and the shape through the mechanochemical feedback ranging from the molecular to the cellular scale. Moreover, the effect of the mechanical perturbation on cells was analyzed by using microstructured surface, which revealed the critical contribution of the mechanical properties of the lamella and cell body for determination of the cell motility and the cell shape.
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