| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
Elastic collagen tubes derived from salmon skin are promising vascular grafts. However, they have some drawbacks such as poor suturability and biodegradability. In this study, we investigated the improvements of mechanical strength and endothelial cell attachment of the collagen tubes by increasing the fibrillar density of collagen matrix, mixing polymers in the collagen matrix, and adsorbing fibronectin on the tubes.
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