| Project/Area Number |
20700397
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
MORI Hideki Osaka Prefecture University, 理学系研究科, 助教 (30450894)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 細胞 / 組織工学 / 神経幹細胞 / 血管内皮細胞 / 血液脳関門 / アルギン酸カルシウムゲル / コラーゲンゲル / 生体材料 |
|---|
| Research Abstract |
In this study, we developed a neural cell sheet, differentiated from neural stem/progenitor cells on a collagen gel cross-linked with water-soluble carbodiimide for elastic modification and deposited on vascular endothelial cells using the transferring technique based on calcium alginate gel behavior, as an alternative functional model for the screening assay targeted delivery across the blood brain barrier.
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