Development of an identification and visualization method for the brain function based on the diffusion tensor MRI

• Project/Area Number: 20700410
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Medical systems
• Research Institution: Kyushu University
• Principal Investigator: KUMAZAWA Seiji Kyushu University, 大学院・医学研究院, 講師 (50363354)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 拡散テンソル / MRI / 白質 / 灰白質 / 領域抽出 / 白質・灰白質

Research Abstract

The purpose of this study was to develop a new brain tissue segmentation method for DT-MRI data in which effect of the partial volume averaging is taken into account. The results of the digital phantom experiment and real DT-MRI data demonstrated that our method improved accuracy in estimation and segmentation of brain tissue on DT-MRI data over the conventional method. Our method may be useful in evaluating the cortical and subcortical diffusivity in neurological diseases.

Research Products

• [Journal Article] Partial Volume Estimation and Segmentation of Brain Tissue Based on Diffusion Tensor MRI (2010)
  • Author(s): Kumazawa S, Yoshiura T, Honda H, Toyofuku F, Higashida Y
  • Journal Title: Med Phys vol.37 Pages: 1482-1490
• [Journal Article] Partial Volume Estimation and Segmentation of Brain Tissue Based on Diffusion Tensor MRI (2010)
  • Author(s): Kumazawa S, et al
  • Journal Title: Medical Physics Volume: 37 Pages: 1482-1490
  • Peer Reviewed
• [Journal Article] Partial Volume Estimation and Segmentation of Brain Tissue Based on Diffusion Tensor MRI (2010)
  • Author(s): Kumazawa S, et al
  • Journal Title: Medical Physics (in press)
  • Peer Reviewed
• [Journal Article] Age-Related Microstructural Changes in Subcortical White Matter During Postadolescent Periods in Men Revealed by Diffusion-Weighted MR Imaging (2009)
  • Author(s): Yoshiura T, Noguchi T, Hiwatashi A, Togao O, Yamashita K, Nakao T, Nagao E, Kumazawa S, Arimura H, Honda H
  • Journal Title: Human brain mapping vol.30 Pages: 3142-3150
• [Presentation] Homomorphic Unsharp Maskingを用いたMR画像信号強度不均一の補正～局所的不均一に対する補正効果の検討～ (2010)
  • Author(s): 甲斐征八, 熊澤誠志
  • Organizer: 九州医療技術学術大会
  • Place of Presentation: 熊本市
  • Year and Date: 2010-11-20
• [Presentation] DT-MRIにおける部分体積効果を考慮した脳皮質領域抽出手法の開発 (2010)
  • Author(s): 熊澤誠志
  • Organizer: 日本磁気共鳴医学会
  • Place of Presentation: つくば市
  • Year and Date: 2010-10-01
• [Presentation] Development of partial volume segmentation of brain tissue based on diffusion tensor imaging(DTI) (2010)
  • Author(s): Kumazawa S
  • Organizer: International Society for Magnetic Resonance in Medicine
  • Place of Presentation: ストックホルム、スウェーデン
  • Year and Date: 2010-05-04
• [Presentation] Influence of a Partial Volume Effect in the Brain Segmentation Based on Diffusion Tensor MRI Data (2009)
  • Author(s): Kumazawa S
  • Organizer: Radiological Society of North America 95th Scientific Assembly and Annual Meeting
  • Place of Presentation: Chicago, USA.
  • Year and Date: 2009-11-30
• [Presentation] Influence of a Partial Volume Effect in the Brain Segmentation Based on Diffusion Tensor MRI Data (2009)
  • Author(s): Kumazawa S, et al
  • Organizer: Radiological Society of North America(RSNA)95th Scientific Assembly and Annual Meeting
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-11-30
• [Presentation] DT-MRIを用いた脳白質・灰白質・脳脊髄液領域抽出手法の開発 (2009)
  • Author(s): 熊澤誠志
  • Organizer: 第37回日本放射線技術学会秋季学術大会
  • Place of Presentation: 岡山市
  • Year and Date: 2009-10-22
• [Presentation] DT-MRIにおける部分体積効果を考慮した脳白質・灰白質・脳脊髄液領域抽出手法の開発 (2009)
  • Author(s): 熊澤誠志
  • Organizer: 第37回日本磁気共鳴医学大会
  • Place of Presentation: 横浜市
  • Year and Date: 2009-10-02
• [Presentation] Influence of a partial volume effect in the segmentation of brain tissue based on diffusion tensor imaging(DTI)data: a digital DTI phantom study (2009)
  • Author(s): Kumazawa S
  • Organizer: International Society for Magnetic Resonance in Medicine
  • Place of Presentation: Honolulu, USA.
  • Year and Date: 2009-04-22
• [Presentation] Influence of a partial volume effect in the segmentation of brain tissue based on diffusion tensor imaging(DTI)data : a digital DTI phantom study (2009)
  • Author(s): Kumazawa S, et al
  • Organizer: International Society for Magnetic Resonance in Medicine
  • Place of Presentation: Honolulu, USA
  • Year and Date: 2009-04-22