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Functional difference and relationship between cerebrum and cerebellum for bimanual coordination

Research Project

Project/Area Number 20700478
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Physical education
Research InstitutionTokyo Metropolitan Organization for Medical Research

Principal Investigator

TOMATSU Saeka  Tokyo Metropolitan Organization for Medical Research, 東京都神経科学総合研究所, 研究員 (00415530)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords脳高次機能学 / 両手協調 / 小脳 / 大脳 / 両手協調動作 / 連関 / 機能差
Research Abstract

The purpose of this study project was to reveal how the cerebrum and the cerebellum share and correlate functions to perform bimanual coordination. Two fMRI studies of human participants revealed that both the cerebral motor-related areas and the cerebellar motor-related areas exhibited activity patterns which reflect temporal patterns of movements, and that all the areas were clearly activated for bimanual coordination. The extracellular recording of cerebellar neuron of monkey performing a step tracking task with its wrist joint revealed that the cerebellum receives the same input as output of the primary motor cortex and the premotor area via mossy fibers during upper limb movement. Moreover, it is possible to say that the cerebellar input layer sharpen the input to convey specific information to Purkinje cells. The neurons in the deep cerebellar nuclei exhibited different functions for movement execution with location, that is, location of their projection. Therefore, it is suggested that the cerebrum and the cerebellum make several loops of function corresponding to the phases of movement execution, and that such control system also work in bimanual coordination.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (12 results)

All 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (10 results)

  • [Journal Article] Temporal feature of BOLD responses varies with temporal patterns of movement.2008

    • Author(s)
      Tomatsu S., Someya Y., Sung TW, Ogawa S., Kakei S.
    • Journal Title

      Neuroscience Research Vol.62、No.3

      Pages: 160-167

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Temporal feature of BOLD responses varies with temporal patterns of movement.2008

    • Author(s)
      Tomatsu S, 他4名
    • Journal Title

      Neuroscience Research 62

      Pages: 160-167

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Difference of information for motor control in input and output signals of the monkey cerebellum.2009

    • Author(s)
      Tomatsu S., Kakei S.
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 小脳における情報処理-入力と出力に含まれる情報の違い-2009

    • Author(s)
      戸松彩花, 筧慎二
    • Organizer
      Motor Control研究会
    • Place of Presentation
      岡崎コンファレンスセンター
    • Year and Date
      2009-05-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 小脳における情報処理-入力と出力に含まれる情報の違い-2009

    • Author(s)
      戸松彩花, 筧慎二
    • Organizer
      Motor Control研究会
    • Place of Presentation
      岡崎
    • Related Report
      2009 Final Research Report
  • [Presentation] Difference of information for motor control in input and output signals of the monkey cerebellum2009

    • Author(s)
      Tomatsu S., Kakei S.
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago
    • Related Report
      2009 Final Research Report
  • [Presentation] Temporal patterns of Golgi cell activities for execution of wrist movements in monkeys.2008

    • Author(s)
      Tomatsu S, 他2名
    • Organizer
      Neuroscience2008
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2008-11-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] Golgi cell activities for execution of wrist movements.2008

    • Author(s)
      Tomatsu S, Kakei S
    • Organizer
      Neuroscience2008
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-07-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] 手首運動における小脳Golgi細胞の活動と役割2008

    • Author(s)
      戸松彩花, 筧慎治
    • Organizer
      Motor Control 研究会
    • Place of Presentation
      岡崎コンファレンスセンター
    • Year and Date
      2008-05-31
    • Related Report
      2008 Annual Research Report
  • [Presentation] 手首運動における小脳Golgi細胞の活動と役割2008

    • Author(s)
      戸松彩花, 筧慎二
    • Organizer
      Motor Control研究会
    • Place of Presentation
      岡崎
    • Related Report
      2009 Final Research Report
  • [Presentation] olgi cell activities for execution of wrist movements.2008

    • Author(s)
      Tomatsu S., Kakei S.
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] Temporal patterns of Golgi cell activities for execution of wrist movements in monkeys.2008

    • Author(s)
      Tomatsu S., Tsunoda Y., Kakei S.
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      Washington
    • Related Report
      2009 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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