Effects of AMP kinase and nitric oxide synthase on skeketal muscle SIRT1 expression
| Project/Area Number |
20700524
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Sports science
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| Research Institution | Tohoku Institute of Technology |
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Principal Investigator |
SUWA Masataka Tohoku Institute of Technology, ライフデザイン学部, 講師 (50464392)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 一酸化窒素合成酵素 / SIRT1 / 骨格筋 / ミトコンドリア生合成 / 持久的トレーニング |
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| Research Abstract |
To estimate the role of AMP-activated protein kinase and nitric oxide synthase on skeletal muscle SIRT1 protein expression, we treated AMP-activated protein kinase activator or nitric oxide synthase inhibitor to rats. The results might suggest that the both of AMP-activated protein kinase and nitric oxide synthase positively regulate the SIRT1 expression in skeletal muscle.
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Report
(3 results)
Research Products
(4 results)
