| Project/Area Number |
20700527
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Sports science
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| Research Institution | Kyorin University |
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Principal Investigator |
SAKURAI Takuya Kyorin University, 医学部, 助教 (20353477)
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| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 運動トレーニング / 脂肪組織 / DNAアレイ / Nox2 / 細胞外マトリックス / 脂肪組織由来幹細胞 / 脂肪細胞分化 / 網羅的遺伝子発現解析 / ペルオキシソーム増殖剤応答性受容体γ / hypoxia-inducible factor-1α / Sfr2 / Prps2 / 酸化ストレス |
|---|
| Research Abstract |
In the present study, DNA array analysis was performed to identify novel genes whose expression was changed in white adipose tissue (WAT) by exercise training (TR) Expression of genes for extracellular matrix-related factors, such as collagen, and NOX2, the catalytic subunit of NADPH oxidase, in WAT was changed by TR. Moreover, TR affected the expression of adipocyte differentiation-related genes in adipose tissue-derived stem cells.
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