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Effects of serotonergic system activation during pedaling exercise on Mind-Body Health

Research Project

Project/Area Number 20700543
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionSeiwa University

Principal Investigator

MASAKI Fumoto  Seiwa University, 法学部, 講師 (40339180)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsセロトニン / 脳波 / 気分 / NIRS / ペダリング運動 / 脳血流 / 侵害受容反射 / 痛覚伝達
Research Abstract

(1) This study demonstrated that pedaling exercise (PE) induces increased activity in the ventral prefrontal cortex (PFC) region, which may be responsible for the accompanying feeling of decreased negative mood with increased vigor-activity. (2) PE induces significant increases in the powers of alpha bands in EEG. These results suggest that such EEG changes are linked with the increased blood 5-HT levels, or an augmentation of the 5-HT system in the brain stem. (3) The activation of the ventral PFC during PE may also be responsible for the augmentation of the 5-HT system. (4) Nociceptive withdrawal reflex was decreased during PE, which indicates that PE suppress nociceptive response via the 5-HT descending inhibitory pathway.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (4 results)

All 2010 2008

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Ventral prefrontal cortex and serotonergic system activation during pedaling exercise induces negative mood improvement and increased alpha band in EEG2010

    • Author(s)
      Fumoto M, Oshima T, Kamiya K, Kikuchi H, Seki Y, Nakatani Y, Yu X, Sekiyama T, Sato-Suzuki I, Arita H
    • Journal Title

      Behavioural Brain Research 213

      Pages: 1-9

    • Related Report
      2009 Final Research Report
  • [Journal Article] Ventral prefrontal cortex and serotonergic system activation during pedaling exercise induces negative mood improvement and increased alpha band in EEG2010

    • Author(s)
      Fumoto M, Oshima T, Kamiya K, Kikuchi H, Seki Y, Nakatani Y, Yu X, Sekiyama T, Sato-Suzuki I, Arita H
    • Journal Title

      Behavioural Brain Research (印刷中,未定)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Cycling exercise produces suppression of nociceptive response in the upper limb and activation of prefrontal cortex : Role of brain serotonergic system2008

    • Author(s)
      Masaki Fumoto
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington DC
    • Year and Date
      2008-11-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] Cycling exercise produces suppression of nociceptive response in the upper limb and activation of prefrontal cortex: Role of brain serotonergic system2008

    • Author(s)
      Fumoto M, Oshima T, Kamiya K, Kikuchi H, Seki Y, Nakatani Y, Yu X, Sekiyama T, Sato-Suzuki I, Arita H
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington DC
    • Related Report
      2009 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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