Elucidation of the Mechanism of non-alcoholic steatohepatitis induced by oxidative stress
| Project/Area Number |
20700550
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied health science
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| Research Institution | Okayama University |
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Principal Investigator |
NAKAMOTO Kazuo Okayama University, 薬学部, 講師 (30432636)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 非アルコール性脂肪性肝炎 / 酸化ストレス / 抗酸化物質 / 予防医学 / NASH / 低酸素 / ミトコンドリア |
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| Research Abstract |
Our present study demonstrated that mitochondrial abnormality might contribute to the progression of NASH in correlation with oxidative stress. Furthermore, Fermented green tea extracts administration prevent the mitochondrial damage and may be beneficial in preventing NASH development.
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Report
(3 results)
Research Products
(11 results)
