| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
(Aim) To clarify the role of PKC-delta on disuse muscle atrophy. (Method) We investigated muscle atrophy and signal transduction of hind-limb model in PKC-delta KO mice. (Result) In PKC-delta KO mice, weight of soleus muscle was lower than those in control mice. Muscle atrophy induced by hind-limb was similar between the groups. (Conclusion) Our result suggested that PKC-delta may contribute to the size of soleus muscle, while it may not affect on disuse muscle atrophy.
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