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Effect of dietary minerals on bone metabolism by molecular nutritional procedure

Research Project

Project/Area Number 20700598
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionTokyo University of Agriculture

Principal Investigator

KATSUMATA Shinichi  Tokyo University of Agriculture, 応用生物科学部, 助教 (10424681)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywordsリン / 鉄 / 骨代謝 / カルシウム吸収 / 鉄欠乏食 / 骨密度 / 骨形成 / 遺伝子発現観察 / 高リン食 / 副甲状腺ホルモン
Research Abstract

This study investigated the effects of high phosphorus diet or iron deficient diet on bone metabolism by molecular nutritional procedure. High phosphorus diet increased mRNA expression of receptor activator of nuclear factor-kappaB ligand and decreased mRNA expressions of intestinal calcium absorption-related factors. Dietary iron deficiency decreased mRNA expressions of osteoblast-related factors and intestinal calcium absorption-related factors.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (7 results)

All 2010 2009

All Presentation (7 results)

  • [Presentation] 鉄欠乏による脂質・骨代謝変動2010

    • Author(s)
      勝間田真一
    • Organizer
      第64回日本栄養・食糧学会大会
    • Place of Presentation
      アスティとくしま
    • Related Report
      2010 Final Research Report
  • [Presentation] 鉄欠乏による脂質・骨代謝変動2010

    • Author(s)
      勝間田真一
    • Organizer
      第64回日本栄養・食糧学会大会
    • Place of Presentation
      アスティとくしま(徳島市)
    • Related Report
      2010 Annual Research Report
  • [Presentation] リンの過剰摂取と骨代謝変動2009

    • Author(s)
      勝間田真一
    • Organizer
      第53回日本薬学会関東支部
    • Place of Presentation
      城西大学薬学部
    • Year and Date
      2009-10-03
    • Related Report
      2010 Final Research Report
  • [Presentation] マウスへの高リン食投与が骨形成関連遺伝子発現に及ぼす影響2009

    • Author(s)
      勝間田真一、上原万里子、鈴木和春
    • Organizer
      第56回日本栄養改善学会学術総会
    • Place of Presentation
      札幌コンベンションセンター
    • Related Report
      2010 Final Research Report
  • [Presentation] マウス骨代謝関連遺伝子発現量に及ぼす高リン食投与および週齢差の影響2009

    • Author(s)
      勝間田真一、上原万里子、鈴木和春
    • Organizer
      第63回日本栄養・食糧学会大会
    • Place of Presentation
      長崎ブリックホール
    • Related Report
      2010 Final Research Report
  • [Presentation] マウス骨代謝関連遺伝子発現量に及ぼす高リン食投与および週齢差の影響2009

    • Author(s)
      勝間田真一
    • Organizer
      第63回日本栄養・食糧学会大会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Related Report
      2009 Annual Research Report
  • [Presentation] マウスへの高リン食投与が骨形成関連遺伝子発現に及ぼす影響2009

    • Author(s)
      勝間田真一
    • Organizer
      第56回日本栄養改善学会学術総会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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