Effect of dietary minerals on bone metabolism by molecular nutritional procedure
Project/Area Number |
20700598
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Eating habits, studies on eating habits
|
Research Institution | Tokyo University of Agriculture |
Principal Investigator |
KATSUMATA Shinichi Tokyo University of Agriculture, 応用生物科学部, 助教 (10424681)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
Keywords | リン / 鉄 / 骨代謝 / カルシウム吸収 / 鉄欠乏食 / 骨密度 / 骨形成 / 遺伝子発現観察 / 高リン食 / 副甲状腺ホルモン |
Research Abstract |
This study investigated the effects of high phosphorus diet or iron deficient diet on bone metabolism by molecular nutritional procedure. High phosphorus diet increased mRNA expression of receptor activator of nuclear factor-kappaB ligand and decreased mRNA expressions of intestinal calcium absorption-related factors. Dietary iron deficiency decreased mRNA expressions of osteoblast-related factors and intestinal calcium absorption-related factors.
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Report
(4 results)
Research Products
(7 results)