| Project/Area Number |
20700600
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
|
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| Research Institution | Tokyo Health Care University |
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Principal Investigator |
SHIMIZU Masatomi Tokyo Health Care University, 医療保健学部, 講師 (90389841)
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|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 抗老化物質 / DNA損傷 / ミトコンドリア / 天然物 / 出芽酵母 / 食品 / 抗変異原物質 / 突然変異 |
|---|
| Research Abstract |
Resveratrol (3,4',5-trihydroxystilbene ; RSV) is a polyphenol found in particularly high concentrations in peanut skin and vine. Here we investigated the anti-mutagenic effects of RSV in Saccharomyces cerevisiae strain 7B. Our results showed that RSV pretreatment for 24 h decreased mutagenesis. Thus the exposure of S. cerevisiae 7B to RSV induces an anti-aging effect. This result raises intense interest for the potentially beneficial effects of RSV on human health.
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