| Project/Area Number |
20700601
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
|
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| Research Institution | Matsumoto University |
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Principal Investigator |
TAKEMURA Hitomi Matsumoto University, 人間健康学部, 助手 (60295558)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | ホルモン依存性癌 / メトキシフラボノイド / Benzo[a]pyrene / CYP / DNA付加体 / アリル炭化水素受容体 / エストロゲン代謝 / がん化学予防 / cytochrome P450 / benzo[a]pyrene / フラボノイド / benzo[a]prene |
|---|
| Research Abstract |
A dietary methoxyflavonoid, chrysoeriol, inhibited the formation of BPDE-DNA adducts in human MCF-7 breast cancer cells, via regulation of the AhR pathway stimulated by benzo[a]pyrene, which is a ubiquitous environmental pollutant.
|
