Elucidation of lipid metabolic disorder and liver injury on the high fat diet
Project/Area Number |
20700603
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Kinjo Gakuin University |
Principal Investigator |
KITAMORI Kazuya Kinjo Gakuin University, 生活環境学部, 講師 (80387597)
|
Project Period (FY) |
2008 – 2009
|
Project Status |
Completed (Fiscal Year 2009)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | NAFLD / NASH / 高脂肪食 / 炎症 / モデル動物 |
Research Abstract |
Patients with nonalcoholic fatty liver disease (NAFLD) are increasing worldwide, and preventive measures are an urgent need and primary concern today. The purpose of this study is to develop and clarify the usefulness of the SHRSP5/Dmcr rat as an animal model for human NAFLD. We have developed animal model of the NAFLD progression as observed in humans using SHRSP5/Dmcr rats fed an HFC diet. This model appears to be useful to investigate the mechanism of human NAFLD progression.
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Report
(3 results)
Research Products
(4 results)