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Effect of funotional food factor in citrus fruits on catecholamine secretion in cultured bovine adrenal medurally cells.

Research Project

Project/Area Number 20700611
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionSeinan Jo Gakuin University

Principal Investigator

SAKAMAKI Ruka  Seinan Jo Gakuin University, 保健福祉学部, 准教授 (80389486)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords神経系 / カテコールアミン / アセチルコリン / 副腎髄質細胞 / フラボノイド / オーラプテン
Research Abstract

In the present study we report the effects of citrus fruit-derived functional food factor on catecholamine secretion in cultured bovine adrenal medullary cells. Auraptene and nomilin decreased catecholamine secretion elicited by acetylcholine and veratridine. Nomi lin modestly inhibited catecholamine secretion elicited by high K. These findings suggest that citrus flavonoids modulate the functions of the adrenal medulla and probably noradrenergic neurons.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (8 results)

All 2010 2009

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results)

  • [Journal Article] Effect of nomilin, citrus limonoid, on catecholamine secretion and noradrenaline uptake in cultured bovine adrenal madullary cells.2010

    • Author(s)
      umiko Toyohira, Ruka Sakamaki, Kojiro Takahashi, Susumu Ueno, Kenji Toyama, Nobuyuki Yanagihara
    • Journal Title

      Journal of Pharmacological sciences VOL.112

      Pages: 193-193

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of nomilin, citrus limonoid, on catecholamine secretion and noradrenaline uptake in cultured bovine adrenal madullary cells2010

    • Author(s)
      Ruka Sakamaki
    • Journal Title

      Journal of Pharmacological Sciences VOL.112

      Pages: 193-193

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of citrus flavonoids on catecholamine secretion in cultured bovine adrenal medullary cells2009

    • Author(s)
      Ruka Sakamaki
    • Journal Title

      Journal of Pharmacological Sciences 109, Suppl

      Pages: 264-264

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Effect of nomilin, citrus limonoid, on cateeholamine Secretion and noradreBaline uptake in cultured bovine adrenal maduUary cells2010

    • Author(s)
      豊平由美子、坂巻路可、高橋浩二郎、上野晋、外由健二、柳原延章
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-03-17
    • Related Report
      2009 Final Research Report
  • [Presentation] Effect of nomilin, citrus limonoid, on catecholamine secretion and noradrenaline uptake in cultured bovine adrenal madullary cells2010

    • Author(s)
      豊平由美子
    • Organizer
      第83回 日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-03-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 柑橘系フラボノイドのカテコールアミン神経系に及ぼす影響-培養ウシ副腎髄質細胞での検討-2009

    • Author(s)
      坂巻路可、豊平由美子、上野晋、高橋浩二郎、外由健二、柳原延章
    • Organizer
      第27回産業医科大学学会総会
    • Place of Presentation
      産業医科大学(福岡)
    • Year and Date
      2009-10-06
    • Related Report
      2009 Final Research Report
  • [Presentation] 柑橘系フラボノイドのカテコールアミン神経系に及ぼす影響―培養ウシ副腎髄質細胞での検討―2009

    • Author(s)
      坂巻路可
    • Organizer
      第27回 産業医科大学学会総会
    • Place of Presentation
      産業医科大学(福岡)
    • Year and Date
      2009-10-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 副腎髄質細胞におけるカテコールアミン分泌に及ぼす柑橘系フラボノイドの影響2009

    • Author(s)
      坂巻路可
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-03-18
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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