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Study on nitrated PAHs formed from reactions on the surface of Asian dust particles

Research Project

Project/Area Number 20710003
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Environmental dynamic analysis
Research InstitutionKanazawa University

Principal Investigator

KAMEDA Takayuki  Kanazawa University, 薬学系, 助教 (50398426)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords黄砂 / 多環芳香族炭化水素 / 二次生成 / 越境輸送 / 多環芳香族炭化水素(PAH) / ニトロ化PAH / 大気内反応
Research Abstract

Polycyclic aromatic hydrocarbons (PAHs) and substituted PAHs such as nitro-PAHs are suspected to concern effects on human health such as mutagenicity, carcinogenicity, endocrine disrupting activities, and so on. Several kinds of the PAH derivatives might be formed via atmospheric reactions of the parent PAHs with inorganic gases such as nitrogen oxides on the Asian dust particles, which is transported from the continent of China to Japan. To test this hypothesis, in this study, we performed chemical reaction experiments of PAHs on the Asian dust particle surface using a reaction-chamber, and investigated the formation of substituted PAHs on the particles.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (42 results)

All 2010 2009 2008 Other

All Journal Article (19 results) (of which Peer Reviewed: 19 results) Presentation (18 results) Book (3 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons2010

    • Author(s)
      X. Yang, K. Igarashi, N. Tang, J. Lin, W. Wang, T. Kameda, A. Toriba, K. Hayakawa
    • Journal Title

      Mutat. Res. 695

      Pages: 29-34

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of particle-associated hydroxynitropyrenes with correction for chemical degradation on a quartz fiber filter during high volume air sampling2010

    • Author(s)
      T.Kameda
    • Journal Title

      Int.J. Environ.Anal.Chem. (in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Indirect- and direct-acting mutagenicity of diesel, coal and wood burning-derived particulates and contribution of polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons2010

    • Author(s)
      X.Yang
    • Journal Title

      Mutat.Res. 695

      Pages: 29-34

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monohydroxylated polycyclic aromatic hydrocarbons inhibit both osteoclastic and osteoblastic activities in teleost scales2009

    • Author(s)
      N. Suzuki, K. Hayakawa, T. Kameda, A. Triba, N. Tang, M.J. Tabata, K. Takada, S. Wada, K. Omori, A.K. Srivastav, H. Mishima, A. Hattori
    • Journal Title

      Life Sci. 84

      Pages: 482-488

    • NAID

      120001256672

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative Stress More Strongly Induced by ortho- Than para-quinoid Polycyclic Aromatic Hydrocarbons in A549 Cells2009

    • Author(s)
      Y. Motoyama, K. Bekki, S-W. Chung, N. Tang, T. Kameda, A. Toriba, K. Taguchi, K. Hayakawa
    • Journal Title

      J. Health Sci. 55

      Pages: 845-850

    • NAID

      130000127977

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of 1-nitropyrene in low volume ambient air samples by high-performance liquid chromatography with fluorescence detection2009

    • Author(s)
      T. Ohno, A. Toriba, T. Kameda, N. Tang, K. Hayakawa
    • Journal Title

      J. Chromatogr. A 1216

      Pages: 4625-4628

    • NAID

      120001342275

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-range transport of fluoride in East Asia monitored at Noto Peninsula2009

    • Author(s)
      X. Yang, M. Yamada, N. Tang, J. -M. Lin, W. Wang, T. Kameda, A. Toriba, K. Hayakawa
    • Journal Title

      Japan, Sci. Total Environ. 407

      Pages: 4681-4686

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of airborne particle-associated benz[a]anthracene-7, 12- quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection2009

    • Author(s)
      T. Kameda, T. Goto, A. Toriba, N. Tang, K. Hayakawa
    • Journal Title

      J. Chromatogr. A 1216

      Pages: 6758-6761

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of airborne particle-associated benz[a]anthracene-7,12-quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection2009

    • Author(s)
      T.Kameda
    • Journal Title

      J.Chromatogr.A 1216

      Pages: 6758-6761

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of 1-nitropyrene in low volume ambient air samples by high-performance liquid chromatography with fluorescence detection2009

    • Author(s)
      T.Ohno
    • Journal Title

      J.Chromatogr.A 1216

      Pages: 4625-4628

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative Stress More Strongly Induced by ortho- Than para-quinoid Polycyclic Aromatic Hydrocarbons in A549 Cells2009

    • Author(s)
      Y.Motoyama
    • Journal Title

      J.Health Sci. 55

      Pages: 845-850

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monohydroxylated polycyclic aromatic hydrocarbons inhibit both osteoclastic and osteoblastic activities in teleost scales2009

    • Author(s)
      N.Suzuki
    • Journal Title

      Life Sci. 84

      Pages: 482-488

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distribution and source of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in Tieling City, Liaoning Province, a typical local city in northeast China2009

    • Author(s)
      N.Tang
    • Journal Title

      Asian Journal of Atmospheric Environment 3

      Pages: 52-58

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Long-range transport of fluoride in East Asia monitored at Noto Peninsula, Japan2009

    • Author(s)
      X.Yang
    • Journal Title

      Sci.Total Environ. 407

      Pages: 4681-4686

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aro matic hydrocarbons in gas/particle phases separately collected by a high-volume a it sampler equipped with a column packed with XAD-4 resin2009

    • Author(s)
      荒木裕樹
    • Journal Title

      J. Health Sci. 55

      Pages: 77-85

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of endocrine disrupting activities of monohydroxylated derivatives of 1-nitropyrene by yeast two-hybrid assay2008

    • Author(s)
      T. Kameda, A. Akiyama, A. Toriba, C. Tachikawa, M. Yoshita, N. Tang, K. Hayakawa
    • Journal Title

      J. Health Sci. 54

      Pages: 118-122

    • NAID

      110006570814

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Direct measurement of the glucuronide conjugate of 1-hydroxypyrene in human urine by using liquid chromatography with tandem mass spectrometry2008

    • Author(s)
      K. Kakimoto, A. Toriba, T. Ohno, M. Ueno, T. Kameda, N. Tang, K. Hayakawa
    • Journal Title

      J. Chromatogr. B 867

      Pages: 259-263

    • NAID

      10028001109

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of endocrine disrupting activities of monohydroxylated derivatives of 1-nitropyrene by yeast two-hybrid assay2008

    • Author(s)
      亀田貴之
    • Journal Title

      J. Health Sci. 54

      Pages: 118-122

    • NAID

      110006570814

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of particle-associated hydroxynitropyrenes with correction for chemical degradation on a quartz fiber filter during high volume air sampling

    • Author(s)
      T. Kameda, A. Akiyama, A. Toriba, N. Tang, K. Hayakawa
    • Journal Title

      Int. J. Environ. Anal. Chem. (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] 大気粒子状物質に含まれる多環芳香族炭化水素キノン類の測定2010

    • Author(s)
      亀田貴之, 後藤知子, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山大学ほか(岡山)
    • Year and Date
      2010-03-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 大気粒子状物質に含まれる多環芳香族炭化水素キノン類の測定2010

    • Author(s)
      亀田貴之
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山大学ほか (岡山県)
    • Year and Date
      2010-03-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 実大気粒子中多環芳香族炭化水素キノン類の観測2009

    • Author(s)
      後藤知子
    • Organizer
      大気環境学会中部支部総会・学術集会
    • Place of Presentation
      金沢勤労者プラザ (石川県)
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] 黄砂表面における有害有機化学物質の非意図的生成と越境輸送の可能性2009

    • Author(s)
      亀田貴之
    • Organizer
      第1回能登総合シンポジウム
    • Place of Presentation
      珠洲市商工会議所 (石川県)
    • Year and Date
      2009-11-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Detemination of airborne particle-associated hydroxynitropyrenes fored via atmospheric photochemical reactions2009

    • Author(s)
      T.Kameda
    • Organizer
      Asia and Africa Science Platform Program Ihtemational Seminar "Environment and Health"
    • Place of Presentation
      第4高等学校記念文化交流館 (石川県)
    • Year and Date
      2009-10-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 黄砂表面における有害有機化学物質の非意図的生成と越境輸送の可能性2009

    • Author(s)
      亀田貴之
    • Organizer
      第3回環日本海域環境シンポジウム
    • Place of Presentation
      第4高等学校記念文化交流館 (石川県)
    • Year and Date
      2009-10-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Determination of airborne particle-associated hydroxynitropyrenes formed via atmospheric photochemical reactions2009

    • Author(s)
      T.Kameda
    • Organizer
      International Society For Polycyclic Aromatic Compounds (ISPAC) 22
    • Place of Presentation
      Francis Marion Hotel (USA)
    • Year and Date
      2009-09-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光反応により生成する大気粒子中新奇ニトロピレン水酸化体の同定および定量2009

    • Author(s)
      亀田貴之, 秋山鮎子, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      第50回大気環境学会年会
    • Place of Presentation
      慶應義塾大学(神奈川)
    • Year and Date
      2009-09-16
    • Related Report
      2009 Final Research Report
  • [Presentation] 光反応により生成する大気粒子中新奇ニトロピレン水酸化体の同定および定量2009

    • Author(s)
      亀田貴之
    • Organizer
      第50回大気環境学会年会
    • Place of Presentation
      慶應義塾大学 (神奈川県)
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 大気内光反応により生成する新奇ニトロピレン水酸化体の同定および定量2009

    • Author(s)
      亀田貴之, 秋山鮎子, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      第18回環境化学討論会
    • Place of Presentation
      つくば国際会議場(茨城)
    • Year and Date
      2009-06-09
    • Related Report
      2009 Final Research Report
  • [Presentation] 大気内光反応により生成する新奇ニトロピレン水酸化体の同定および定量2009

    • Author(s)
      亀田貴之
    • Organizer
      第18回環境化学討論会
    • Place of Presentation
      つくば国際会議場 (茨城県)
    • Year and Date
      2009-06-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光反応によって二次生成するニトロピレン水酸化体の大気内動態2009

    • Author(s)
      亀田貴之, 秋山鮎子, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      日本薬学会第129回年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2009-03-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 光反応により二次生成するヒドロキシニトロピレンの大気内動態2008

    • Author(s)
      亀田貴之, 秋山鮎子, 中山侑希, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      大気環境学会中部支部総会・学術集会
    • Place of Presentation
      富山県民会館(富山)
    • Year and Date
      2008-11-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 光酸化反応によって生成するニトロピレン水酸化体の大気内動態2008

    • Author(s)
      亀田貴之, 秋山鮎子, 中山侑希, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      第49回大気環境学会年会
    • Place of Presentation
      金沢大学(石川)
    • Year and Date
      2008-09-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 大気浮遊粒子中2-ニトロフルオランテン光分解生成物の分析2008

    • Author(s)
      亀田貴之, 秋山鮎子, 鳥羽陽, 唐寧, 早川和一
    • Organizer
      第49回大気環境学会年会
    • Place of Presentation
      金沢大学(石川)
    • Year and Date
      2008-09-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 光酸化反応によって生成するニトロピレン水酸化体の大気内動態2008

    • Author(s)
      亀田貴之
    • Organizer
      第49回大気環境学会年会
    • Place of Presentation
      金沢
    • Year and Date
      2008-09-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] 中国の上海, 瀋陽における大気粉じん中多環芳香族炭化水素の比較2008

    • Author(s)
      唐寧
    • Organizer
      第49回大気環境学会年会
    • Place of Presentation
      金沢
    • Year and Date
      2008-09-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒドロキシ-1-ニトロピレンの内分泌かく乱作用および大気環境中動態2008

    • Author(s)
      亀田貴之, 秋山鮎子, 中山侑希, 鳥羽 陽, 唐寧, 早川和一
    • Organizer
      第17回環境化学討論会
    • Place of Presentation
      神戸国際会議場(兵庫)
    • Year and Date
      2008-06-11
    • Related Report
      2009 Final Research Report
  • [Book] Photochemical degradation of selected nitro- and oxy-polycyclic aromatic hydrocarbons on airborne particles under simulated solar UV-irradiation, Airborne Particulates, (Ming Cheng and Wen Liu, eds. )2009

    • Author(s)
      T. Kameda, Y. Nakayama, T. Goto, T. Koyanagi, H. Bandow, K. Fujimori, A. Toriba, N. Tang, K. Hayakawa
    • Publisher
      Nova Science Publishers
    • Related Report
      2009 Final Research Report
  • [Book] Aiborne Particulates2009

    • Author(s)
      T.Kameda, et al
    • Total Pages
      343
    • Publisher
      Nova Science Publishers
    • Related Report
      2009 Annual Research Report
  • [Book] Airborne Particulates

    • Author(s)
      亀田貴之
    • Publisher
      Nova Science Publishers(In press)
    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] 芳香族ニトロ化合物の製造方法2009

    • Inventor(s)
      亀田貴之, 松木篤
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2009-246879
    • Filing Date
      2009-10-27
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] 芳香族ニトロ化合物の製造方法2009

    • Inventor(s)
      亀田貴之 松木篤
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2009-246879
    • Filing Date
      2009-10-27
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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