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Direct observation of clustered DNA damage using time-of-flight ion mass spectrometer

Research Project

Project/Area Number 20710048
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Risk sciences of radiation/Chemicals
Research InstitutionJapan Atomic Energy Agency

Principal Investigator

FUJII Kentaro  Japan Atomic Energy Agency, 先端基礎研究センター, 副主任研究員 (00360404)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsクラスターDNA損傷 / 軟X線 / イオン / 質量分析 / 電離放射線 / DNA / クラスター損傷 / 放射光
Research Abstract

To investigate the production mechanism of clustered DNA damage, I developed the time-of-flight ion mass spectrometer. If the two ions were produced by a single photon, the coincidence signal can be detected on the ion mass spectrum. Moreover, I measured the clustered DNA lesions induced by monochromatic soft X-rays by an enzymatic method.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (65 results)

All 2011 2010 2009 2008 Other

All Journal Article (24 results) (of which Peer Reviewed: 24 results) Presentation (36 results) Book (3 results) Remarks (2 results)

  • [Journal Article] EPR study of unoccupied electron species in thin films of pyrimidine bases induced by nitrogen and oxygen K-shell photoabsorption2011

    • Author(s)
      岡壽崇
    • Journal Title

      Appl.Phys.Lett.

      Volume: 98

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel technique using DNA denaturation to detect multiply induced single-strand breaks in a hydrated plasmid DNA molecule by X-ray and 4He2+ ion irradiation2011

    • Author(s)
      横谷明徳
    • Journal Title

      Radiat.Protect.Dosim.

      Volume: 143 Pages: 219-225

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A model for analysis of the yield and the level of clustering of radiation-induced DNA strand breaks in hydrated plasmids2011

    • Author(s)
      鹿園直哉
    • Journal Title

      Radiat.Protect.Dosim.

      Volume: 143 Pages: 181-185

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 軟X線照射によるDNA損傷の光子エネルギーによる選択的な依存性(放射線化学会奨励賞受賞記事)2010

    • Author(s)
      藤井健太郎
    • Journal Title

      放射線化学 90

      Pages: 17-22

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 軟X線照射によるDNA損傷の光子エネルギーによる選択的な依存性2010

    • Author(s)
      藤井健太郎
    • Journal Title

      放射線化学

      Volume: 90 Pages: 17-22

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] X-ray absorption spectra for nucleotides (AMP, GMP, and CMP) in liquid water solutions near the nitrogen K-edge.2010

    • Author(s)
      鵜飼正敏
    • Journal Title

      Chem.Phys.Let.

      Volume: 495 Pages: 90-95

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Protective effect of silybin and analogues against X-ray radiation-induced damage2010

    • Author(s)
      Fu, H.
    • Journal Title

      Acta Biochim.Biophys.Sin.

      Volume: 42 Pages: 489-495

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spectral Change of X-ray Absorption Near Edge Structure of DNA Thin Films Irradiated with Monochromatic Soft X-rays.2009

    • Author(s)
      K.Fujii, A.Yokoya
    • Journal Title

      Radiation Physics and Chemistry 78

      Pages: 1188-1191

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nucleobase Lesions and Strand Breaks in Dry DNA Thin Films Selectively Induced by Monochromatic Soft X-rays.2009

    • Author(s)
      K.Fujii, N.Shikazono, A.Yokoya
    • Journal Title

      Journal of Physical Chemistry B 113

      Pages: 16007-16015

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nucleobase Lesions and Strand Breaks in Dry DNA Thin Films Selectively Induced by Monochromatic Soft X-rays2009

    • Author(s)
      K.Fujii, N.Shikazono, A.Yokoya
    • Journal Title

      Journal of Physical Chemistry B 113

      Pages: 16007-16015

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spectral Change of X-ray Absorption Near Edge Structure of DNA Thin Films Irradiated with Monochromatic Soft X-rays2009

    • Author(s)
      K.Fujii, A.Yokoya
    • Journal Title

      Radiation Physics and Chemistry 78

      Pages: 1188-1191

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] EPR Study of Radiation Damage to DNA Irradiated with Synchrotron S oft X-rays around Nitrogen and Oxygen K-edge2009

    • Author(s)
      A.Yokoya, K.Fujii, Y.Fukuda, M.Ukai
    • Journal Title

      Radiation Physics and Chemistry 78

      Pages: 1211-1215

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synchrotron Radiation Photoelectron Studies for Primary Radiation Effects using a Liquid Water Jet in Vacuum : Total and Partial Photoelectron Yields for Liquid Water Near the Oxygen K-edge2009

    • Author(s)
      M.Ukai, A.Yokoya, Y.Nonaka, K.Fujii, Y.Saitoh
    • Journal Title

      Radiation Physics and Chemistry 78

      Pages: 1202-1206

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Free Radical Scavenging and Radioprotective Effects of Carnosine and Anserine2009

    • Author(s)
      H.Fu, Y.Katsumura, M.Lin, Y.Muroya, K.Hata, K.Fujii, A.Yokoya, Y.Hatano
    • Journal Title

      Radiation Physics and Chemistry 78

      Pages: 1192-1197

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spectral Change of X-ray Absorption Near Edge Structure of DNA Thin Films Irradiated with Monochromatic Soft X-rays2009

    • Author(s)
      K. Fujii, A. Yokoya
    • Journal Title

      Radiation Physics and Chemistry (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] EPR Study of Radiation Damage to DNA Irradiated with Synchrotron Soft X-rays around Nitrogen and Oxygen K-edge2009

    • Author(s)
      A. Yokoya, K. Fujii, Y. Fukuda, M. Ukai
    • Journal Title

      Radiation Physics and Chemistry (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synchrotron Radiation Photoelectron Studies for Primary Radiation Effects using a Liquid Water Jet in Vacuum : Total and Partial Photoelectron Yields for Liquid Water Near the Oxygen K-edge2009

    • Author(s)
      M. Ukai, A. Yokoya, Y. Nonaka, K. Fujii, Y. Saitoh
    • Journal Title

      Radiation Physics and Chemistry (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Yield, Processing, and Biological Consequences of Clustered DNA Damage Induced by Ionizing Radiation2009

    • Author(s)
      N. Shikazono, M. Noguchi, K. Fujii, A. Urushibara, A. Yokoya
    • Journal Title

      Journal of Radiation Research 50

      Pages: 27-36

    • NAID

      110007042080

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Induction of Single Strand Breaks, and Base Lesions in Plasmid DNA Films Induced by Carbon, Nitrogen, and Oxygen KLL Auger Process.2008

    • Author(s)
      K.Fujii, A.Yokoya, N.Shikazono
    • Journal Title

      International Journal of Radiation Biology 84

      Pages: 1104-1111

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Induction of Single Strand Breaks, and Base Lesions in Plasmid DNA Films Induced by Carbon, Nitrogen, and Oxygen KLL Auger Process2008

    • Author(s)
      K. Fujii, A. Yokoya, N. Shikazono
    • Journal Title

      International Journal of Radiation Biology 84

      Pages: 1104-1111

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Studies of Soft X-ray-induced Auger Effect on the Induction of DNA Damage2008

    • Author(s)
      A. Yokoya, K. Fujii, N. Shikazono, K. Akamatsu, A. Urushibara, R. Watanabe
    • Journal Title

      International Journal of Radiation Biology 84

      Pages: 1069-1081

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of Lesions Induced in Linear-formed Plasmid DNA by Valence Ionization and Auger Decay at Carbon, Nitrogen and Osygen2008

    • Author(s)
      K. Akamatsu, K. Fujii, A. Yokoya
    • Journal Title

      International Journal of Radiation Biology 84

      Pages: 1082-1092

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DNA Damage Induced by the Direct Effect of Radiation2008

    • Author(s)
      A. Yokoya, N. Shikazono, K. Fujii, A. Urushibara, K. Akamatsu, R. Watanabe
    • Journal Title

      Radiation Physics and Chemistry 77

      Pages: 1280-1285

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] X-ray Absorption Spectrum for Guanine-5'-monophosphate in Water Solution in the Vicinity of the Nitrogen K-edge Observed in Free Liquid Jet in Vacuum2008

    • Author(s)
      M. Ukai, A. Yokoya, K. Fujii, Y. Saitoh
    • Journal Title

      Radiation Physics and Chemistry 77

      Pages: 1265-1269

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 酸素K殻共鳴励起によりプラスミドDNA中に生成する鎖切断、塩基変異及びAPサイト2011

    • Author(s)
      菅谷雄基
    • Organizer
      第24回日本放射光学会年会
    • Place of Presentation
      つくば市
    • Year and Date
      2011-01-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 軟X線照射したDNA薄膜のXANESスペクトル変化2011

    • Author(s)
      藤井健太郎、横谷明徳
    • Organizer
      第24回日本放射光学会年会
    • Place of Presentation
      つくば市
    • Year and Date
      2011-01-09
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 酸素・窒素のK殻イオン化でDNA関連分子薄膜中に生じた不対電子種のESRによる測定2011

    • Author(s)
      岡壽崇
    • Organizer
      第24回日本放射光学会年会
    • Place of Presentation
      つくば市
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] プラスミドDNAの変性-アニーリングを利用した多重塩基損傷検出のための新しい方法の開発2010

    • Author(s)
      横谷明徳
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都市
    • Year and Date
      2010-10-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 軟X線及び電子線照射によりプラスミドDNA中に生成する塩基損傷およびAPサイト2010

    • Author(s)
      菅谷雄基
    • Organizer
      日本放射線影響学会第53回大会
    • Place of Presentation
      京都市
    • Year and Date
      2010-10-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 軟X線照射によるDNA 損傷の光子エネルギーによる選択的な依存性(学会奨励賞受賞講演)2010

    • Author(s)
      藤井健太郎
    • Organizer
      第53回放射線化学討論会
    • Place of Presentation
      名古屋市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 軟X線照射によるDNA損傷の光子エネルギーによる選択的な依存性2010

    • Author(s)
      藤井健太郎
    • Organizer
      第53回放射線化学討論会
    • Place of Presentation
      名古屋市
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Near Edge X-ray Absorption Fine Structure of DNA Thin Film Irradiated with Soft X-rays.2010

    • Author(s)
      K.Fujii, A.Yokoya
    • Organizer
      37th International Conference on Vacuum Ultraviolet and X-ray physics.
    • Place of Presentation
      バンクーバー(カナダ)
    • Year and Date
      2010-07-12
    • Related Report
      2010 Final Research Report
  • [Presentation] Near Edge X-ray Absorption Fine Structure of DNA Thin Film Irradiated with Soft X-rays2010

    • Author(s)
      藤井健太郎
    • Organizer
      37th International Conference on Vacuum Ultraviolet and X-ray physics
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-07-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 単色軟X線による乾燥DNA中に生じる分子変化の照射エネルギー依存性2010

    • Author(s)
      藤井健太郎、鹿園直哉、横谷明徳
    • Organizer
      第23回日本放射光学会年会
    • Place of Presentation
      姫路
    • Year and Date
      2010-01-06
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 酸素及び窒素のK殻イオン化によりDNA関連分子薄膜中に生じた不対電子種のEPR観測2010

    • Author(s)
      横谷明徳、藤井健太郎、福田義博、鵜飼正敏
    • Organizer
      第23回日本放射光学会年会
    • Place of Presentation
      姫路
    • Year and Date
      2010-01-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] 単色軟X線によるDNA鎖切断および塩基損傷の選択的誘発2009

    • Author(s)
      藤井健太郎、鹿園直哉、横谷明徳
    • Organizer
      日本放射線影響学会第52回大会
    • Place of Presentation
      広島市
    • Year and Date
      2009-11-11
    • Related Report
      2010 Final Research Report
  • [Presentation] 単色軟X線によるDNA鎖切断および塩基損傷の選択的誘発2009

    • Author(s)
      藤井健太郎、鹿園直哉、横谷明徳
    • Organizer
      日本放射線影響学会第52回大会
    • Place of Presentation
      広島
    • Year and Date
      2009-11-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] イオンビーム照射により高水和DNAフィルム中に誘発されるDNA鎖切断および塩基損傷収率のLET依存性2009

    • Author(s)
      横谷明徳、鈴木雅雄、牛込剛史、田内広、鶴岡千鶴、野口実穂、藤井健太郎、鹿園直哉、渡邊立子
    • Organizer
      日本放射線影響学会第52回大会
    • Place of Presentation
      広島
    • Year and Date
      2009-11-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] A Novel Technique using DNA Denatureation to Detect Multiplly Induced Single-Strand Breaks in a Hydrated Plasmid DNA Molecule by X-ray and He Ion Irradiation2009

    • Author(s)
      A.Yokoya, N.Shikazono, A.Urushibara, M.Noguchi, K.Fujii
    • Organizer
      15th International Symposium on Microdosimetry : An International Meeting on Ionizing Radiation Quality, Molecular Mechanisms, Cellular Effects, an Their Consequences for Low Level Risk Assessment and Radiation Therapy
    • Place of Presentation
      Verona, Italy
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analysis on the Yield and the Level of Clustering of Radiation-Induced DNA Strand Breaks in Hydrated Plasmids2009

    • Author(s)
      N.Shikasono, A.Yokoya, A.Urushibara, M.Noguchi, K.Fujii
    • Organizer
      15th International Symposium on Microdosimetry : An International Meeting on Ionizing Radiation Quality, Molecular Mechanisms, Cellular Effects, an Their Consequences for Low Level Risk Assessment and Radiation Therapy
    • Place of Presentation
      Verona, Italy
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Near Edge X-ray Absorption Fine Structure of DNA Thin Films Irradiated with soft X-rays.2009

    • Author(s)
      K.Fujii, A.Yokoya
    • Organizer
      11th International Conference on Electronic Spectroscopy & Structure
    • Place of Presentation
      奈良市
    • Year and Date
      2009-10-06
    • Related Report
      2010 Final Research Report
  • [Presentation] Near Edge X-ray Absorption Fine Structure of DNA Thin Films Irradiated with soft X-rays2009

    • Author(s)
      藤井健太郎, 横谷明徳
    • Organizer
      11th International Conference on Electronic Spectroscopy & Structure
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2009-10-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Synchrotron Radiation Photoelectron Studies for Primary Radiation Effects in Biosolutions : Two Dimensional Electron Spectra for Liquid Water in the Soft X-ray Region2009

    • Author(s)
      M.Ukai, Y.Nonaka, R.Sumiya, S.Yashiro, A.Yokoya, K.Fujii, Y.Saitoh
    • Organizer
      11th International Conference on Electronic Spectroscopy & Structure
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2009-10-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] プラスミドDNAに対する高LET放射線による非DSB性多重SSB誘発の可能性2008

    • Author(s)
      横谷明徳, 鹿園直哉, 藤井健太郎
    • Organizer
      日本放射線影響学会第51回大会
    • Place of Presentation
      北九州市
    • Year and Date
      2008-11-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] X線誘発損傷に対するシリビンとその類似体のin vitroでのDNA防護効果2008

    • Author(s)
      付海英, 林銘章, 端邦樹, 室屋裕佐, 藤井健太郎, 勝村庸介, 横谷明徳, 鹿園直哉, 籏野嘉彦
    • Organizer
      日本放射線影響学会第51回大会
    • Place of Presentation
      北九州市
    • Year and Date
      2008-11-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] 軟X線照射によって乾燥プラスミドDNAに生じる分子損傷の収率2008

    • Author(s)
      藤井健太郎、横谷明徳、鹿園直哉
    • Organizer
      第51回放射線化学討論会
    • Place of Presentation
      つくば市
    • Year and Date
      2008-10-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 軟X線照射によって乾燥プラスミドDNAに生じる分子損傷の収率2008

    • Author(s)
      藤井健太郎, 横谷明徳, 鹿園直哉
    • Organizer
      第51回放射線化学討論会
    • Place of Presentation
      つくば
    • Year and Date
      2008-10-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] Free Radical Scavenging Properties of Carnosine and Related Compounds2008

    • Author(s)
      H. Y. Fu, Y. Katusmura, M. Lin, Y. Muroya, K. Hata, K. Fujii, A. Yokoya
    • Organizer
      第51回放射線化学討論会
    • Place of Presentation
      つくば
    • Year and Date
      2008-10-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] 軟X線によってDNA分子内に生じるサイト選択的分子変化2008

    • Author(s)
      藤井健太郎、横谷明徳、鹿園直哉
    • Organizer
      分子科学討論会
    • Place of Presentation
      福岡市
    • Year and Date
      2008-09-25
    • Related Report
      2010 Final Research Report
  • [Presentation] 軟X線によってDNA分子内に生じるサイト選択的分子変化2008

    • Author(s)
      藤井健太郎, 横谷明徳, 鹿園直哉
    • Organizer
      分子科学討論会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Spectral Change of X-ray Absorption Near Edge Structure of DNA Thin Films Irradiated with Monochromatic Soft X-rays.2008

    • Author(s)
      K.Fujii, A.Yokoya
    • Organizer
      2nd Asia-Pasific Symposium on Radiation Chemistry
    • Place of Presentation
      東京都
    • Year and Date
      2008-08-31
    • Related Report
      2010 Final Research Report
  • [Presentation] Spectral Change of X-ray Absorption Near Edge Structure of DNA Thin Films Irradiated with Monochromatic Soft X-rays2008

    • Author(s)
      K. Fujii, A. Yokoya
    • Organizer
      2nd Asia-Pasific Symposium on Radiation Chemistry
    • Place of Presentation
      東京
    • Year and Date
      2008-08-31
    • Related Report
      2008 Annual Research Report
  • [Presentation] EPR Study of Radiation Damage to DNA Irradiated with Synchrotron Soft X-rays around Nitrogen and Oxygen K-edge2008

    • Author(s)
      A. Yokoya, K. Fujii
    • Organizer
      2nd Asia-Pasific Symposium on Radiation Chemistry
    • Place of Presentation
      東京
    • Year and Date
      2008-08-31
    • Related Report
      2008 Annual Research Report
  • [Presentation] Synchrotron Radiation Photoelectron Studies for Primary Radiation Effects in Bio-solutions : Electron Spectra for Liquid Water and Absorption Spectra for Nucleotides in the Soft X-ray Region2008

    • Author(s)
      M. Ukai, A. Yokoya, Y. Nonaka, K. Fujii, Y. Saitoh
    • Organizer
      2nd Asia-Pasific Symposium on Radiation Chemistry
    • Place of Presentation
      東京
    • Year and Date
      2008-08-31
    • Related Report
      2008 Annual Research Report
  • [Presentation] Lethality and Mutagenesis of E. coli Cells Irradiated with Soft X-rays2008

    • Author(s)
      T. Suzaka, N. Shikazono, K. Fujii, A. Yokoya, H. Tauchi
    • Organizer
      2nd Asia-Pasific Symposium on Radiation Chemistry
    • Place of Presentation
      東京
    • Year and Date
      2008-08-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Qualitative Analysis on the Yield of Radiation-induced DNA Strand Breaks in Hydrated Plasmids2008

    • Author(s)
      N. Shikazono, A. Urushibara, K. Fujii, A. Yokoya
    • Organizer
      2nd Asia-Pasific Symposium on Radiation Chemistry
    • Place of Presentation
      東京
    • Year and Date
      2008-08-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Photoelectron Study for DNA and its Damages in Solution using Monochromatic Soft X-rays : Total and Partial Yields of Photoelectrons for Water and Nucleotides2008

    • Author(s)
      M. Ukai, A. Yokoya, Y. Nonaka, K. Fujii, Y. Saitoh
    • Organizer
      10th International Workshop Radiation Damage to DNA
    • Place of Presentation
      Urabandai, Japan
    • Year and Date
      2008-06-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] DNA Damage Spectra in Ultrasoft X-ray Region : Effect of Inner-shell Ionization of Carbon, Nitrogen and Oxygen Atoms on the Damage Induction.2008

    • Author(s)
      K.Fujii, A.Yokoya, N.Shikazono
    • Organizer
      10th International Workshop Radiation Damage to DNA
    • Place of Presentation
      裏磐梯
    • Year and Date
      2008-06-09
    • Related Report
      2010 Final Research Report
  • [Presentation] DNA Damage Specrtra in Ultrasoft X-ray Region : Effect of Inner-shell Ionization of Carbon, Nitrogen and Oxygen Atoms on the Damage Induction2008

    • Author(s)
      K. Fujii, A. Yokoya, N. Shikazono
    • Organizer
      10th International Workshop Radiation Damage to DNA
    • Place of Presentation
      Urabandai, Japan
    • Year and Date
      2008-06-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Novel Technique using DNA Denaturation to Detect Prompt and Enzymatically Induced Single Strand Breaks Produced in a Clustered Damage Site2008

    • Author(s)
      A. Yokoya, N. Shikazono, A. Urushibara, K. Fujii
    • Organizer
      10th International Workshop Radiation Damage to DNA
    • Place of Presentation
      Urabandai, Japan
    • Year and Date
      2008-06-09
    • Related Report
      2008 Annual Research Report
  • [Book] Chap.20 : R Spectroscopic study of radiation-induced DNA lesions and their susceptibility to enzymatic repair. In Charged Particle and Photon Interactions with Matter-Recent Advances, Applications, and Interfaces2010

    • Author(s)
      横谷明徳
    • Publisher
      CRC/Taylor & Francis Group
    • Related Report
      2010 Annual Research Report
  • [Book] Spectroscopic study of radiation-induced DNA lesions and their susceptibility to enzymatic repair, in Charged Particle and Photon Interactions with Matter-Recent Advances, Applications, and Interfaces(ed.by Y.Hatano, Y.Katsumura, A.Mozumder)2010

    • Author(s)
      A.Yokoya, K.Fujii, N.Shikazono, M.Ukai
    • Publisher
      Talor & Francis(印刷中)
    • Related Report
      2009 Annual Research Report
  • [Book] In Charged Particle and Photon Interactions with Matter-Recent Advances, Applications, and Interfaces-(Chap.20 : R Spectroscopic study of radiation-induced DNA lesions and their susceptibility to enzymatic repair.)(ed.by Y.Hatano, Y.Katsumura, and A.Mozumder)

    • Author(s)
      A.Yokoya, K.Fujii, N.Shikazono, M.Ukai
    • Publisher
      CRC/Taylor & Francis Group, USA
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • URL

      http://jglobal.jst.go.jp/detail.php?JGLOBAL_ID=200901099565273528&t=1&d=1&q=%28205%29%3D5000101360

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://asrc.jaea.go.jp/soshiki/gr/eng/mysite3/index.html

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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