| Project/Area Number |
20710098
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Tokyo University of Technology |
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Principal Investigator |
AKIMOTO Takuo Tokyo University of Technology, 応用生物学部, 講師 (90367194)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | バイオチップ / 蛍光 / バイオ関連機器 / マイクロアレイ / プロテインチップ / 偏光 |
|---|
| Research Abstract |
Fluorescence from an optical waveguide substrate fabricated with a metal and a dielectric was known to be enhanced more than 100 factors. It has been found in recent year that the fluorescence enhancement depends on the polarization of excitation light. Motivated by this finding, we attempted to develop an instrument for highly sensitive detection of fluorescence employing the polarization dependence of the optical waveguide substrate. As a result, approximately 10-times increase of the sensitivity and S/N ratio could be achieved.
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