• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of solid-state calcium-43 NMR

Research Project

Project/Area Number 20750022
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Physical chemistry
Research InstitutionTokyo Institute of Technology

Principal Investigator

YAMADA Kazuhiko  Tokyo Institute of Technology, 大学院・理工学研究科, 助教 (80373380)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsカルシウム / NMR / 生物物理 / タンパク質 / 蛋白質 / 酵素
Research Abstract

A solid-state calcium-43 Nuclear Magnetic Resonance (NMR) is proposed for investigation of the molecular dynamics of calcium atoms and ions in biological compounds. Although ^1H, ^<13>C, and ^<15>N NMR spectroscopy has made a tremendous impact on the development of biological sciences, much less is known about calcium-43 NMR of biological compounds. In this work, I try to develop the fundamental of spectral analysis for half-integer quadrupole nuclei and possibly the unexplored field of solid-state ^<43>Ca NMR for applications to biological molecules.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (15 results)

All 2011 2010 2009 2008

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (6 results) Book (1 results)

  • [Journal Article] N-(Fluoren-9-ylmethoxycarbonyl)-Laspartic acd 4-tert-butyl ester2009

    • Author(s)
      山田和彦、橋爪大輔、清水禎
    • Journal Title

      Acta Cryst. E65

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] N-(Fluoren-9-ylmethoxycarbonyl)-L-isoleucine2008

    • Author(s)
      山田和彦、橋爪大輔、清水禎、出口健三
    • Journal Title

      Acta Cryst. E64

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] N-(Fluoren-9-ylmethoxycarbonyl)-L-leucine2008

    • Author(s)
      山田和彦、橋爪大輔、清水禎
    • Journal Title

      Acta Cryst. E64

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Determination of the orientations for the ^<17>O NMR tensors in a polycrystalline L-alanine hydrochloride2008

    • Author(s)
      山田和彦、清水禎、山崎俊夫、大木忍
    • Journal Title

      Solid State Nuclear Magnetic Resonance 33

      Pages: 88-94

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Asolid-state ^<17>O NMR study of β-glycine : High sensitivity of ^<17>O NMR parameters to H-bonding interactions2008

    • Author(s)
      山田和彦、清水禎、山崎俊夫、佐藤明
    • Journal Title

      Chemistry Letters 37

      Pages: 472-473

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A solid-state ^<17>O NMR, X-ray, and quantum chemical study of N-α-Fmoc-protected amino acids2008

    • Author(s)
      山田和彦、橋爪大輔、清水禎、大木忍、横山茂之
    • Journal Title

      Journal of Molecular Structure 888

      Pages: 187-196

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Asolid-state ^<17>O NMR study of L-phenylalanine and L-valine hydrochlorides2008

    • Author(s)
      山田和彦、清水禎、大木忍、山崎俊夫
    • Journal Title

      Magnetic Resonance in Chemistry 46

      Pages: 226-234

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Experimental determination of orientations for ^<17>O electric-field-gradient and chemical shielding tensors in L-alanine2008

    • Author(s)
      山田和彦、清水禎、淺沼美和子、山崎俊夫、横山茂之
    • Journal Title

      Solid State Nuclear Magnetic Resonance 33

      Pages: 25-30

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Presentation] 半整数四極子核固体NMRスペクトル解析の基礎と応用2010

    • Author(s)
      山田和彦
    • Organizer
      第48回固体NMR・材料フォーラム及び第5回NIMSナノ計測センターシンポジウム
    • Place of Presentation
      物質・材料研究機構(茨城県つくば市)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 有機・生体分子系のための半整数四極子核固体NMR法の開発2009

    • Author(s)
      山田和彦
    • Organizer
      高分子学会NMR研究会
    • Place of Presentation
      東京工業大学
    • Year and Date
      2009-05-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 生体分子系固体NMR法の開発2008

    • Author(s)
      山田和彦
    • Organizer
      第43回固体NMR・材料フォーラム
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2008-05-12
    • Related Report
      2009 Final Research Report
  • [Presentation] Understanding of ^<17>O NMR tensors in biological solids2008

    • Author(s)
      山田和彦
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      米国サンディエゴ
    • Related Report
      2009 Final Research Report
  • [Presentation] Both experimental and theoretical investigations of ^<17>O NMR tensors in biological solids2008

    • Author(s)
      山田和彦、清水禎、横山茂之、大木忍
    • Organizer
      Gordon Research Conference Computational Aspects-biomolecular NMR
    • Place of Presentation
      イタリア・バーガ
    • Related Report
      2009 Final Research Report
  • [Presentation] Asolid-state NMR study of small biological compounds2008

    • Author(s)
      山田和彦、清水禎、山崎俊夫、大木忍
    • Organizer
      Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      米国カリフォルニア
    • Related Report
      2009 Final Research Report
  • [Book] Annual Reports on NMR spectroscopy, Vol 70. Chapter 3.2011

    • Author(s)
      K.Yamada
    • Total Pages
      43
    • Publisher
      Elsevier Ltd., Academic Press
    • Related Report
      2009 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi