Total Synthesis of Biologically Active Compounds PossessingCyclohexylamine Skeleton.
| Project/Area Number |
20750036
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
ISHIKAWA Hayato Tokyo University of Science, 工学部, 助教 (80453827)
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| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 有機合成化学 / 有機触媒 / ワンポット反応 / オセルタミビル / ABT-341 / ドミノ反応 / マイクロフローシステム / カラムフリー合成 / カナマイシンA / パンクラチスタチン |
|---|
| Research Abstract |
Efficient total synthesis of Anti-Influenza drug Oseltamivir and diabetes drug ABT-341 were accomplished. The key process of the synthesis for applied to the industrial scale, is our originally developed asymmetric organocatalytic reactions, domino reaction and one-pot process.
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Report
(3 results)
Research Products
(32 results)
