Creation of chiral macromolecules with self-replicating and improving abilities

• Project/Area Number: 20750037
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Organic chemistry
• Research Institution: Tokyo University of Science
• Principal Investigator: KAWASAKI Tsuneomi Tokyo University of Science, 総合研究機構, 講師 (40385513)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 不斉自己触媒反応 / ピリミジルアルカノール / 不斉増幅 / デンドリマー / 自己複製 / 自己改善 / ポリスチレン / クリプトキラリティー / 巨大分子 / 不斉自己増殖

Research Abstract

Alkylsilane dendrimers with multi-functionalities of asymmetric autocatalysis were synthesized by the coupling reaction between the dendritic core and pyrimidine moieties. It was found that the chiral dendritic macromolecules possess the ability of the asymmetric autocatalytic self-replication and self-improvement. In addition, the discrimination of cryptochirality of isotactic polystyrene has been achieved in conjunction with asymmetric autocatalysis.

Research Products

• [Journal Article] Reversal Phenomenon of Enantioface Selectivity by the Cooperative Operation of Two Chiral Catalysts (2011)
  • Author(s): Tsuneomi Kawasaki
  • Journal Title: CHEMICAL COMMUNICATIONS Volume: 47 Pages: 5277-5279
  • Peer Reviewed
• [Journal Article] Enantioselective Synthesis Induced by Chiral Crystal Composed of DL-Serine in Conjunction with Asymmetric Autocatalysis (2011)
  • Author(s): Tsuneomi Kawasaki
  • Journal Title: ORGANIC LETTERS Volume: 13
  • Peer Reviewed
• [Journal Article] Enantioselective Synthesis Induced by Compounds with Chirality Arising from Partially Deuterated Methyl Groups in Conjunction with Asymmetric Autocatalysis (2011)
  • Author(s): Tsuneomi Kawasaki
  • Journal Title: CHEMISTRY LETTERS Volume: 40 Pages: 320-321
  • NAID: 10027816038
  • Peer Reviewed
• [Journal Article] Spontaneous absolute asymmetric synthesis promoted by achiral amines in conjunction with asymmetric autocatalysis (2010)
  • Author(s): Kenta Suzuki
  • Journal Title: JOURNAL OF SYSTEMS CHEMISTRY Volume: 1 Pages: 5-5
  • Peer Reviewed
• [Journal Article] Amplification of chirality as a pathway to biological homochirality (2010)
  • Author(s): Tsuneomi Kawasaki
  • Journal Title: JOURNAL OF FLUORINE CHEMISTRY Volume: 131 Pages: 525-534
  • Peer Reviewed
• [Journal Article] Asymmetric Autocatalysis Induced by Chiral Crystals of Achiral Tetraphenylethylenes (2010)
  • Author(s): Tsuneomi Kawasaki, Mai Nakaoda, Nobuhiro Kaito, Taisuke Sasagawa, Kenso Soai
  • Journal Title: ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE 40 Pages: 65-78
  • Peer Reviewed
• [Journal Article] Generation of Absolute Controlled Crystal Chirality by the Removal of Crystal Water from Achiral Crystal of Nucleobase Cytosine (2010)
  • Author(s): Tsuneomi Kawasaki, Yuko Hakoda, Hiroko Mineki, Kenta Suzuki, Kenso Soai
  • Journal Title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132 Pages: 2874-2875
  • Peer Reviewed
• [Journal Article] Discrimination of Cryptochirality in Chiral Isotactic Polystyrene by Asymmetric Autocatalysis (2009)
  • Author(s): Tsuneomi Kawasaki, Christiane Hohberger, Yuko Araki, Kunihiko Hatase, Klaus Beckerle, Jun Okuda, Kenso Soai
  • Journal Title: Chem. Commun. Pages: 5621-5623
  • Peer Reviewed
• [Journal Article] Asymmetric autocatalysis. Automultiplication of chiral molecules (2009)
  • Author(s): Kenso Soai, Tsuneomi Kawasaki
  • Journal Title: CHIMICA OGGI-CHEMISTRY TODAY 27 Pages: 3-7
  • Peer Reviewed
• [Journal Article] 展望:同位体不斉が引き起こす不斉自己触媒反応-ホモキラリティーの起源としての同位体不斉- (2009)
  • Author(s): Tsuneomi Kawasaki, Kenso Soai
  • Journal Title: Isotope News 11 Pages: 2-6
  • Peer Reviewed
• [Journal Article] 不斉現象に新事実炭素同位体で光学活性体に偏りが生じる! (2009)
  • Author(s): 破合憲三・川崎常臣
  • Journal Title: 化学(Chemistry) 64 Pages: 38-43
  • Peer Reviewed
• [Journal Article] Discrimination of Cryptochirality in Chiral Isotactic Polystyrene by Asymmetric Autocatalysis (2009)
  • Author(s): Tsuneomi Kawasaki, Christiane Hohberger, Yuko Araki, Kunihiko Hatase, Klaus Beckerle, Jun Okuda, Kenso Soai
  • Journal Title: CHEMICAL COMMUNICATIONS 2009 Pages: 5621-5623
  • Peer Reviewed
• [Journal Article] 炭素同位体(^<13>C/^<12>C)置換キラル化合物による不斉合成-不斉自己触媒反応を用いて- (2009)
  • Author(s): 川暗常臣
  • Journal Title: 化学と工業(Chemistry & Chemical Industry) 62 Pages: 898-900
  • Peer Reviewed
• [Journal Article] Asymmetric Autocatalysis Induced by Meteoritic Amino Acids with Hydrogen Isotope Chirality (2009)
  • Author(s): Tsuneomi Kawasaki, Masako Shimizu, Daisuke Nishiyama, Masateru Ito, Hitomi Ozawa, Kenso Soai
  • Journal Title: CHEMICAL COMMUNICATIONS 2009 Pages: 4396-4398
  • Peer Reviewed
• [Journal Article] Asymmetric Autocatalysis Triggered by Carbon Isotope (13C/12C) Chirality (2009)
  • Author(s): Tsuneomi Kawasaki, Yukari Matsumura, Takashi Tsutsumi, Kenta Suzuki, Masateru Ito, Kenso Soai
  • Journal Title: SCIENCE 324 Pages: 492-495
  • Peer Reviewed
• [Journal Article] 研究室紹介-北から南から- (2009)
  • Author(s): 破合憲三・川崎常臣
  • Journal Title: Organometallic News 2009 Pages: 20-21
• [Journal Article] Highly enantioselective asymmetric autocatalysis using chiral ruthenium complex-ion-exchanged synthetic hectorite as a chiral initiator (2009)
  • Author(s): Tsuneomi Kawasaki
  • Journal Title: ORGANIC & BIOMOLECULAR CHEMISTRY 7 Pages: 1073-1075
  • Peer Reviewed
• [Journal Article] 不斉自己触媒反応を用いて不斉の起源に迫る (2008)
  • Author(s): 〓合憲三
  • Journal Title: 化学と教育 56 Pages: 384-385
• [Journal Article] Enantioselective Synthesis Utilizing Enantiomorphous Organic Crystal of Achiral Benzils as a Source of Chirality in Asymmetric Autocatalysis (2008)
  • Author(s): Tsuneomi Kawasaki
  • Journal Title: ORGANIC LETTERS 10 Pages: 4085-4088
  • Peer Reviewed
• [Journal Article] ホモキラリティーの起源解明への化学的アプローチー不斉自己触媒反応を用いて- (2008)
  • Author(s): Kenso Soai
  • Journal Title: Fine Chemicals 37 Pages: 5-16
  • Peer Reviewed
• [Presentation] 炭素および水素同位体キラル化合物が引き起こす不斉自己触媒反応 (2011)
  • Author(s): 川崎常臣
  • Organizer: 第28回千葉地域活動若手セミナー(招待講演)
  • Place of Presentation: 千葉・東京理科大学野田キャンパス
  • Year and Date: 2011-03-10
• [Presentation] 炭素および水素同位体キラル化合物が引き起こす不斉自己触媒反応 (2011)
  • Author(s): 川崎常臣
  • Organizer: 第28回千葉地域活動若手セミナー
  • Place of Presentation: 千葉・東理大
  • Year and Date: 2011-03-10
• [Presentation] DL-セリンが形成するキラル結晶を不斉源とする不斉自己触媒反応 (2011)
  • Author(s): 笹川泰介
  • Organizer: The 2nd Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 東京・早稲田大学
  • Year and Date: 2011-03-02
• [Presentation] 不斉の起源としてのアキラルな核酸塩基が形成するキラル結晶 (2011)
  • Author(s): 峯木紘子
  • Organizer: The 2nd Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 東京・早稲田大学
  • Year and Date: 2011-03-02
• [Presentation] 炭素同位体キラル化合物による不斉誘起と不斉自己触媒による高感度不斉認識 (2011)
  • Author(s): 川崎常臣
  • Organizer: 日本農芸化学会関東支部2010年度第2回支部例会シンポジウム
  • Place of Presentation: 東京・東大
• [Presentation] アキラルグリシン臭化水素酸塩が形成するキラル結晶を不斉開始剤とする不斉自己触媒反応 (2011)
  • Author(s): 佐藤奨
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 横浜・神奈川大学
• [Presentation] ピリミジン-5-カルバルデヒド単結晶のエナンチオトピック面を利用したジアルキル亜鉛不斉付加反応と引き続く不斉自己触媒反応 (2011)
  • Author(s): 上村紗耶香
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 横浜・神奈川大学
• [Presentation] 同一の面選択性を示す2種のキラル触媒を用いたエナンチオ選択性の逆転現象(4) (2011)
  • Author(s): 涌島勇貴
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 横浜・神奈川大学
• [Presentation] Chiral Discrimination of Carbon and Hydrogen Isotope Enantiomers by Asymmetric Autocatalysis (2010)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 8th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2010-12-01
• [Presentation] Asymmetric Autocatalysis Mediated by Ferroelectric Triglycine Sulfate (2010)
  • Author(s): Susumu Sato
  • Organizer: 8th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2010-12-01
• [Presentation] Chiral Crystal of Achiral Pyrimidine-5-carbaldehyde Acts as Source of Chirality and Reactant for Asymmetric Autocatalysis (2010)
  • Author(s): Sayaka Kamimura
  • Organizer: 8th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2010-12-01
• [Presentation] Adsorption structures of pyrimidine derivatives observed with atomic force microscopy (AFM) at chiral HgS(10-10) surfaces. (2010)
  • Author(s): Hitoshi Shindo
  • Organizer: 8th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2010-12-01
• [Presentation] Reversal of Enantioselectivity by Two Chiral Aminoalcohols Catalysts in Conjunction with Asymmetric Autocatalysis (2010)
  • Author(s): Yuki Wakushima
  • Organizer: 7th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2010-09-29
• [Presentation] tereospecific Formation of Chiral Cytosine Crystal by Dehydration from Achiral Cytosine? monohydrate Crystal (2010)
  • Author(s): Hiroko Mineki
  • Organizer: 7th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2010-09-29
• [Presentation] Asymmetric Autocatalysis Triggered by Carbon and Hydrogen Isotope Chirality (2010)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 3rd Microsymposium on Asymmetric Catalysis
  • Place of Presentation: Warsaw, Polish Academy of Sciences
  • Year and Date: 2010-09-09
• [Presentation] キラル化合物の高感度不斉認識-不斉自己触媒反応を用いて- (2010)
  • Author(s): 川崎常臣
  • Organizer: 特定非営利活動法人科学知総合研究所(SKIL)第23回合同研究会
  • Place of Presentation: 東京・東大
  • Year and Date: 2010-08-27
• [Presentation] Recent Aspects of Asymmetric Autocatalysis (2010)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 2nd International Symposium on the Soai Reaction and Related Topic
  • Place of Presentation: Mocsolad, Hungary
• [Presentation] 不斉自己触媒反応を用いるキラルセンシング (2010)
  • Author(s): 川崎常臣
  • Organizer: 日本化学会第4回関東支部大会
  • Place of Presentation: つくば・筑波大
• [Presentation] Asymmetric Amplification Induced By Chirally Crystallized Racemic Serine In Conjunction With Asymmetric Autocatalysis (2010)
  • Author(s): Taisuke Sasagawa
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] Asymmetric Induction By Static Electric Field Using Ferroelectric Triglycine Sulfate In Conjunction With Asymmetric Autocatalysis (2010)
  • Author(s): Susumu Sato
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] Reversal Of Enantioface Selectivity By Combination Of Two Chiral Catalysts Of The Same Enantioface Selectivity (2010)
  • Author(s): Yuki Wakushima
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] Absolute Control Of Helical Molecular Arrangement Of Cytosine Crystal By The Crystal Face Selective Dehydration Of Crystal Water (2010)
  • Author(s): Hiroko Mineki
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] Single Crystal Structures Of Asymmetric Autocatalyst. Isopropylzinc Alkoxide Of Pyrimidyl Alkanol (2010)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] Determination Of Absolute Structure And Optical Rotatory Dispersion Of Gamma-Glycine (2010)
  • Author(s): Kazuhiko Ishikawa
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] Asymmetric Autocatalysis Using Chiral Crystal Of Achiral Pyrimidine-5-Carbaldehyde As The Substrate And Source Of Chirality (2010)
  • Author(s): Sayaka Kamimura
  • Organizer: 22nd Internal Symposium on Chirality (Chirality 2010/ISCD-22)
  • Place of Presentation: Sapporo
• [Presentation] 二つのキラルなアミノアルコール混合触媒系におけるエナンチオ選択性の逆転現象 (2010)
  • Author(s): 涌島勇貴
  • Organizer: 平成22年度有機合成化学北陸セミナー
  • Place of Presentation: 金沢・石川県青少年総合研修センター
• [Presentation] DL-セリンが形成するラセミ化合物のキラル結晶を不斉源とする不斉自己触媒反応 (2010)
  • Author(s): 笹川泰介
  • Organizer: 平成22年度有機合成化学北陸セミナー
  • Place of Presentation: 金沢・石川県青少年総合研修センター
• [Presentation] 水素同位体置換による不斉を有するアミノ酸及びその誘導体を不斉源とする不斉自己触媒反応 (2010)
  • Author(s): 小澤瞳
  • Organizer: 平成22年度有機合成化学北陸セミナー
  • Place of Presentation: 金沢・石川県青少年総合研修センター
• [Presentation] アキラルな核酸塩基シトシンのキラル結晶を不斉開始剤として用いる不斉自己触媒反応 (2010)
  • Author(s): 峯木紘子
  • Organizer: 平成22年度有機合成化学北陸セミナー
  • Place of Presentation: 金沢・石川県青少年総合研修センター
• [Presentation] (日)炭素同位体キラル化合物による不斉誘導現象の発見と超高感度不斉認識(英)Asymlnetric Induction Arising from Enantiomerically Enriched Carbon-13 Isotopomers and Highly Sensitive Chiral Discrimination (2010)
  • Author(s): 川暗常臣
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] キラルなHgS(10-10)表面へのピリミジン誘導体の吸着のAFM観察 (2010)
  • Author(s): 城田雄亮・二木かおり・新藤斎・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] 同一の面選択性を示す2種のキラル触媒を用いたエナンチオ選択性の逆転現象(3) (2010)
  • Author(s): 塩沢和也・涌島勇貴・朝比奈真維・木下智之・Luts Francois・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] アキラルグリシン塩酸塩が形成するキラル結晶を不斉開始剤とする不斉自己触媒反応 (2010)
  • Author(s): 貝戸信博・鈴木健太・佐藤奨・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] アキラルグリシン硫酸塩が形成するキラル強誘電体結晶を不斉開始剤とする不斉自己触媒反応 (2010)
  • Author(s): 佐藤奨・鈴木健太・貝戸信博・川崎常臣・朝日透・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] DL-セリンラセミ化合物が形成するキラル結晶を不斉開始剤とする不斉自己触媒反応 (2010)
  • Author(s): 笹川泰介・鈴木健太・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] 2-(2-ジメチルフェニルシリルビニル)ピリミジン-5-カルバルデヒドのキラル結晶を不斉源とする高エナンチオ選択的不斉合成 (2010)
  • Author(s): 上村紗耶香・鈴木健太・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] 単結晶X線構造解析に基づく不斉自己触媒の構造(2) (2010)
  • Author(s): 飛田隆行・笹川泰介・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] 核酸塩基シトシン-水和物アキラル結晶の脱水によるキラリティー発生制御と不斉自己触媒反応 (2010)
  • Author(s): 峯木紘子・箱田裕子・鈴木健太・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] 同一の面選択性を示す2種のキラル触媒を用いたエナンチオ選択性の逆転現象(2) (2010)
  • Author(s): 涌島勇貴・塩沢和也・朝比奈真維・木下智之・Lutz Francois・川崎常臣・〓合憲三
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪・近畿大
• [Presentation] 炭素同位体置換によるキラル化合物が引き起こす不斉自己触媒反応 (2009)
  • Author(s): 川暗常臣
  • Organizer: 錯体化学若手の会関東支部平成21年度第2回勉強会
  • Place of Presentation: 東京・東京理科大学
  • Year and Date: 2009-11-28
• [Presentation] Asymmetric Autocatalysis with Amplification of ee Induced by Chiral Crystals of Achiral Tetrakis(p-halophenyl)ethylenes (2009)
  • Author(s): Nobuhiro Kaito, Taisuke Sasagawa, Mai Nakaoda, Tsuneomi Kawasaki, Kenso Soai
  • Organizer: 6^<th> Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2009-11-25
• [Presentation] Asymmetric Amplification Induced by Chiral Crystal Formed from Racemic Serine in Combination with Asymmetric Autocatalysis (2009)
  • Author(s): Taisuke Sasagawa, Kenta Suzuki, Tsuneomi Kawasaki, Kenso Soai
  • Organizer: 6^<th> Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2009-11-25
• [Presentation] X-ray Single Crystal Structure of Asymmetric Autocatalyst (2009)
  • Author(s): Takayuki Tobita, Taisuke Sasagawa, Tsuneomi Kawasaki, Kenso Soai
  • Organizer: 6th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2009-11-25
• [Presentation] アキラル化合物の不斉結晶化によるキラリティーの発現と不斉自己触媒による高エナンチオ選択的不斉合成反応 (2009)
  • Author(s): 川崎常臣
  • Organizer: 第23回若い世代の特別講演会(日本化学会第89春季年会)
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] 同一の面選択性を示すキラル触媒混合系におけるエナンチオ選択性の逆転現象 (2009)
  • Author(s): 涌島勇貴
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] アキラルなテトラフェニルエチレン及びその誘導体が形成するキラル有機結晶を不斉源として用いる不斉自己触媒反応 (2009)
  • Author(s): 貝戸信博
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] 水素同位体置換による不斉を有するアミノ酸及びその誘導体を不斉源とする不斉自己触媒反応 (2009)
  • Author(s): 小澤瞳
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] 不斉自己触媒反応を用いた炭素同位体置換キラル化合物の不斉認識(3) (2009)
  • Author(s): 松村友香里
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] 単結晶X線構造解析に基づく不斉自己触媒の構造 (2009)
  • Author(s): 飛田隆行
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] アキラル核酸塩基シトシンのキラル結晶を不斉の起源とする不斉自己触媒反応(2) (2009)
  • Author(s): 峯木紘子
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] アキラルな物質存在下での不斉自己触媒による自発的絶対不斉合成 (2009)
  • Author(s): 峯木紘子・鈴木健太・箱田裕子・川崎常臣・挾合憲三
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
  • Year and Date: 2009-03-28
• [Presentation] アイソタクチックなポリスチレンオリゴマーを不斉開始剤として用いる不斉自己触媒反応 (2009)
  • Author(s): 荒木裕子・畑瀬國彦・川崎常臣・奥田純・〓合憲三
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 船橋・日大工学部船橋キャンパス
• [Presentation] Hydrogen isotope substituted chiral meteoritic amino acids triggered asymmetric autocatalysis with amplification of chirality (2009)
  • Author(s): Tsuneomi Kawasaki, Hitomi Ozawa, Masateru Ito, Daisuke Nishiyama, Masako Shimizu, Kenso Soai
  • Organizer: COST-ESF Conference SYSTEMS CHEMISTRY II : EVOLUTION AND SYSTEMS
  • Place of Presentation: Anna Grand Hote, Balaton fured, Lake Balaton, Hungary
• [Presentation] Formation of Chiral Crystal of Cytosine with the Desired Chirality from Achiral Cytosine Without Using Chiral Auxiliary (2009)
  • Author(s): Tsuneomi Kawasaki, Yuko Hakoda, Hiroko Mineki, Kenta Suzuki, Kenso Soai
  • Organizer: COST-ESF Conference SYSTEMS CHEMISTRY II : EVOLUTION AND SYSTEMS
  • Place of Presentation: Anna Grand Hote, Balaton fured, Lake Balaton, Hungary
• [Presentation] 炭素および水素同位体置換キラル化合物が誘起する不斉自己触媒反応 (2009)
  • Author(s): 川崎常臣・小澤瞳・鈴木健太・松村友香里・伊藤真央・西山大亮・清水雅子・〓合憲三
  • Organizer: The Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 東京・早稲田大学小野記念講堂
• [Presentation] Reversal of enantioselectivity by mixing two chiral ligands in asymmetric addition of dialkylzinc in conjunction with asymmetric autocatalysis (2009)
  • Author(s): Tsuneomi Kawasaki, Yuki Wakushima, Mai Asahina, Tomoyuki Kinoshita, Francois Lutz, Kenso Soai
  • Organizer: The 238th National Meeting & Exposition of the American Chemical Society (ACS)
  • Place of Presentation: Washington, DC・Walter E.Washington Convention Center
• [Presentation] Discrimination of Cryptochirality in Isotactic Polystyrene by Asymmetric Autocatalysis (2009)
  • Author(s): Tsuneomi Kawasaki, Yuko Araki, Kunihiko Hatase, Jun Okuda, Kenso Soai
  • Organizer: 21st Internal Symposium on Chirality (Chirality2009)
  • Place of Presentation: Colorado・Beaver Run Conference Center
• [Presentation] Formation of Chiral Crystal from Achiral Crystal and Enantioselective Synthesis Induced by Chiral Crystal of Achiral Nucleobase Cytosine in Combination with Asymmetric Autocatalysis (2009)
  • Author(s): Kenta Suzuki, Yuko Hakoda, Hiroko Mineki, Tsuneomi Kawasaki, Kenso Soai
  • Organizer: 21st Internal Symposium on Chirality (Chirality2009)
  • Place of Presentation: Colorado・Beaver Run Conference Center
• [Presentation] 水素・重水素同位体不斉を有するキラルエステル及びアミノ酸を不斉源とする不斉自己触媒反応 (2009)
  • Author(s): 小澤瞳・伊藤真央・川暗常臣・破合憲三
  • Organizer: シンポジウム「モレキュラー・キラリティー2009」(MC2009)
  • Place of Presentation: 大阪・大阪大学
• [Presentation] アキラルな核酸塩基シトシンのキラル結晶を不斉源とする不斉自己触媒反応 (2009)
  • Author(s): 鈴木健太・峯木紘子・箱田裕子・川崎常臣・そ合憲三
  • Organizer: シンポジウム「モレキュラー・キラリティー2009」(MC2009)
  • Place of Presentation: 大阪・大阪大学
• [Presentation] アミノアルコール触媒におけるエナンチオ選択性の逆転現象 (2009)
  • Author(s): 涌島勇貴・朝比奈真維・木下智之・Lutz Francois・川崎常臣・そ合憲三
  • Organizer: シンポジウム「モレキュラー・キラリティー2009」(MC2009)
  • Place of Presentation: 大阪・大阪大学
• [Presentation] アキラルな有機化合物が形成するキラル結晶を不斉開始剤とする不斉自己触媒反応 (2009)
  • Author(s): 鈴木健太、箱田裕子、峯木紘子、畑瀬国彦、原田勇輝、飛田隆行、川崎常臣、〓合憲三
  • Organizer: 第57回有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 東京・早稲田大学(西早稲田キャンパス)
• [Presentation] Asymmetric Autocatalysis Induced by Chiral Crystals Composed of Achiral Organic and Inorganic Compounds as the Possible Route for the Origin and Evolution of Chirality (2008)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 2nd TUS International Collaboration Workshop -Joint Symposium with International Industry-Academia-Government Collaboration-
  • Place of Presentation: Tokyo, Hotel Metropolitan Edmont
  • Year and Date: 2008-12-10
• [Presentation] Spontaneous Absolute Asymmetric Synthesis Mediated by Achiral Amines in Conjunction with Asymmetric Autocatalysis (2008)
  • Author(s): Kenta Suzuki
  • Organizer: 5th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2008-12-01
• [Presentation] Asymmetric Autocatalysis Using Carbon Isotope Substituted Chiral Corn pounds (2008)
  • Author(s): Yukari Matsumura
  • Organizer: 5th Symposium on Chemical Approaches to Chira lity
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2008-12-01
• [Presentation] Discrimination of Cryptochirality in Isotactic Polystyrene Oligomer in Conjunction with Asymmetric Autocatalysis (2008)
  • Author(s): Yuko Araki
  • Organizer: 5th Symposium on Chemical Approaches to Chirality
  • Place of Presentation: Tokyo・Tokyo University of Science
  • Year and Date: 2008-12-01
• [Presentation] Creation of Chiral Dendritic Macromolecules with the Functionalities of Self-Replication and Self-improvement in Combination with Asymmetric Autocatalysis (2008)
  • Author(s): Tsuneomi Kawasaki, Mai Nakaoda, Yutaro Takahashi, Yusuke Kanto, Nanako Kuruhara, Kenji Hosoi, Kenso Soai
  • Organizer: ESF-COST High-Level Research Conference -Systems Chemistry-
  • Place of Presentation: Maratea・Italy
• [Presentation] Spontaneous Absolute Asymmetric Synthesis in the Presence of Achiral Amine in Coniunction with Asymmetric Autocatalysis (2008)
  • Author(s): Kenta Suzuki
  • Organizer: ESF-COST High-Level Research Conference -Systems Chemistry-
  • Place of Presentation: Maratea, Italy, Hotel Villa del Mare
• [Presentation] Creation of chiral dendritic macromolecules with the functionalities of self-replication and self-improvement in combination with asymmetric autocatalysis (2008)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: ESF-COST High-Level Research Conference -Systems Chemistry-
  • Place of Presentation: Maratea, Italy, Hotel Villa del Mare
• [Presentation] Chiral Crystals of Achiral Biological Compounds as an Origin of Homochirality of Biomolecules in Conjunction with Asymmetric Autocatalysis (2008)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 15th International Conference on the Origin of Life (Florence ISSOL'08)
  • Place of Presentation: Florence・Palazzo degli Affari
• [Presentation] Cinnabar, naturally occurring enantiomorphous mineral, mediated enantioselective synthesis of organic compound in conjunction with asymmetri cautocatalysis (2008)
  • Author(s): Tsuneomi Kawasaki
  • Organizer: 20th International Symposium on Chirality (ISCD-20, Chirality 2008)
  • Place of Presentation: Geneva・University of Geneva
• [Presentation] 不斉自己触媒による不斉識別反応の開発および炭素同位体不斉の超高感度不斉認識への展開 (2008)
  • Author(s): 川崎常臣
  • Organizer: シンポジウム「モレキュラー・キラリティー2008」(MC2008)
  • Place of Presentation: 岡山・岡山大学創立五十周年記念館
• [Presentation] 天然由来のキラル無機結晶である辰砂を不斉源とする不斉自己触媒反応 (2008)
  • Author(s): 鈴木健太
  • Organizer: シンポジウム「モレキュラー・キラリティー2008」(MC2008)
  • Place of Presentation: 岡山・岡山大学創立五十周年記念館
• [Presentation] アキラルなテトラフェニルエチレンが形成するキラル結晶を不斉開始剤として用いる高エナンチオ選択的不斉自己触媒反応 (2008)
  • Author(s): 中小田舞
  • Organizer: シンポジウム「モレキュラー・キラリティー2008」(MIC2008)
  • Place of Presentation: 岡山・岡山大学創立五十周年記念館
• [Book] Asymmetric Amplification and Autocatalysis in Catalytic Asymmetric Synthesis, Third Edition, Ed.by Iwao Ojima (2010)
  • Author(s): Kenso Soai, Tsuneomi Kawasaki, Takanori Shibata
  • Total Pages: 40
  • Publisher: John Wiley & Sons, Inc.(Hoboken, New Jersey)
• [Book] Asymmetric Amplification and Autocatalysis in Catalytic Asymmetric Synthesis, Third Edition, Ed. by Iwao Ojima (2010)
  • Author(s): Kenso Soai, Tsuneomi Kawasaki, Takanori Shibata
  • Total Pages: 998
  • Publisher: John Wiley & Sons, Inc. (Hoboken, New Jersey)
• [Book] Asymmetric Autocatalysis of Pyrimidyl Alkanol Using an Organozinc Reagent in Organometallic Chirality, eds. by G. Palyi, C. Zucchi, L. Caglioti (2008)
  • Author(s): Kenso Soai
  • Total Pages: 19
  • Publisher: Accademia Nazionale di Scienze, Lettere e Arti - Mucchi Editore, Modena
• [Book] Asymmetric autocatalysis with amplification of chirality in Topics In Current Chemistry Vol. 284 (Amplification of Chirality) (2008) eds. by K. Soai (2008)
  • Author(s): Kenso Soai
  • Total Pages: 33
  • Publisher: Springer-Verlag Berlin
• [Remarks] ホームページ等
  • URL: http://www.rs.kagu.tus.ac.jp/soai/KawasakiT_engl.html
• [Remarks]
  • URL: http://www.rs.kagu.tus.ac.jp/soai/KawasakiT.html
• [Remarks]
  • URL: http://www.rs.kagu.tus.ac.jp/soai/KawasakiT.html
• [Remarks]
  • URL: http://www.rs.kagu.tus.ac.jp/soai/KawasakiT.html
• [Patent(Industrial Property Rights)] 5-ピリミジルアルカノール化合物の製造方法 (2010)
  • Inventor(s): 〓合憲三・川崎常臣
  • Industrial Property Rights Holder: 学校法人東京理科大学
  • Filing Date: 2010-03-11