| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Research Abstract |
1) The device of near-infrared Suface Plasmon field-enhanced Fluorescence Spectroscopy (SPFS) measurement was constructed by the visible optical suface plasmon field-enhanced fluorescence measurement device improvement.
2) The fast quantification of the tumor marker (AFP ; alpha fetoprotein) with near-infrared SPFS was done. The plasma sample would be measured in 15 minutes, it improved by about 20 times compared with the visible SPFS and the limit of detection was 0.005 ng/mL.
3) It searched for the near-infrared fluorescent probe. The nonspecific adsorption of single-walled carbon nanotube (SWNT) to the sensor surface could not be controlled, and it did not arrive at the spectrum evaluation of characteristics. By taking the appropriate distance of the interval with the sensor surface (surface of gold thin film), it was very high sensitivity when the organic dye was used.
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