Development of Compact Disk Type Surface Plasmon Resonance Sensor

• Project/Area Number: 20750063
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Analytical chemistry
• Research Institution: Tokyo Metropolitan University
• Principal Investigator: NAKAJIMA Hizuru Tokyo Metropolitan University, 都市環境科学研究科, 准教授 (10432858)
• Project Period (FY): 2008 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: チップ分析 / μTAS / Lab-on-a-chip / マイクロチップ / 化学センサ / バイオセンサ / オンサイト測定 / SPR / CD / uTAS / 表面プラズモン共鳴

Research Abstract

A compact disk (CD) type microfluidic device and a rotation device were developed and the flow control based on centrifugal force was evaluated. The introduction sequence of the several solutions into the microchannel could be controlled by changing the rotation speed of the CD. An SPR sensor based on grating coupler was developed and the sensor was successfully applied to the determination of IgA. The SPR sensor developed in this study does not require expensive prism and matching oil. Since the pumps and valves are unnecessary, the sensor would be useful for on-site analysis.

Research Products

• [Journal Article] A Surface Plasmon Resonance Sensor on a Compact Disk-Like Microfluidic Device (2009)
  • Author(s): Hemmi, H. Nakajima, A. Moto, T. Usui, T. Tobita, N. Soh, K. Nakano, K. Uchiyama, T. Imato
  • Journal Title: Proceedings of theμTAS 2009 Pages: 998-1000
  • Peer Reviewed
• [Journal Article] A Surface Plasmon Resonance Sensor on a Compact Disk-Like Microfluidic Device (2009)
  • Author(s): A.Hemmi, H.Nakajima, A.Moto, T.Usui, T.Tobita, N.Soh, K.Nakano, K.Uchiyama, T.Imato
  • Journal Title: The Proceedidngs of μ TAS 2009 1 Pages: 998-1000
  • Peer Reviewed
• [Journal Article] Flow immunoassay for nonionic sunfactants based on surface plasmon resonance sensors (2009)
  • Author(s): M.Tanaka, K.Sakamoto, H.Nakajima, N.Soh, K.Nakano, T.Masadome, T.Imato
  • Journal Title: Analytical Sciences 25 Pages: 999-1005
  • Peer Reviewed
• [Journal Article] Sequential injection flow immunoassay based on surface plasmon resona nce sensors (2008)
  • Author(s): Mayumi Tanaka, et.al.
  • Journal Title: Journal of Flow Injection Analysis 25 Pages: 172-182
  • Peer Reviewed
• [Journal Article] マイクロチップを用いる化学分析システム (2008)
  • Author(s): 中嶋秀ら
  • Journal Title: 分離技術 38 Pages: 381-386
  • Peer Reviewed
• [Journal Article] Flow sandwich immunoassay for specific anti-OVA IgG antibody by use of surface plasmon resonance sensor (2008)
  • Author(s): Yan Li, et.al.
  • Journal Title: Talanta 77 Pages: 473-478
  • Peer Reviewed
• [Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device (2010)
  • Author(s): A. Hemmi, T. Tobita, A. Moto, T. Imato, T. Usui, K. Uchiyama, H. Nakajima
  • Organizer: Pittcon2010
  • Place of Presentation: Orland, Florida, USA
  • Year and Date: 2010-03-01
• [Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device (2010)
  • Author(s): Akihide Hemmi, Tatsuya Tobita, Akihiro Moto, Toshihiko Imato, Takashi Usui, Katsumi Uchiyama, Hizuru Nakajima
  • Organizer: Pittcon2010
  • Place of Presentation: 米国フロリダ州オーランド
• [Presentation] Surface plasmon resonance immunosor using power free pump (2010)
  • Author(s): Tatsuya Tobita, Akihide Hemmi Hizuru Nakajima, Toshihiko Imato
  • Organizer: Pittcon2010
  • Place of Presentation: 米国フロリダ州オーランド
• [Presentation] A Surface Plasmon Resonance Sensor on a Compact Disk-Like Microfluidic Device (2009)
  • Author(s): A. Hemmi, H. Nakajima, A. Moto, T. Usui, T. Tobita, N. Soh, K. Nakano, K. Uchiyama, T. Imato
  • Organizer: μTAS
  • Place of Presentation: Jeju, Korea
  • Year and Date: 2009-11-03
• [Presentation] コンパクトディスク型表面プラズモン共鳴センサの開発 (2009)
  • Author(s): 臼井崇, 本明紘, 辺見彰秀, 飛田達也, 宗伸明, 中野幸二, 今任稔彦, 中嶋秀, 内山一美
  • Organizer: 東京コンファレンス2009
  • Place of Presentation: 幕張メッセ国際会議場
  • Year and Date: 2009-09-04
• [Presentation] A Surface Plasmon Resonance Sensor on a Compact Disk-Like Microfluidic Device (2009)
  • Author(s): H. Nakajima, A. Hemmi, A. Moto, T. Tobita, N. Soh, K. Nakano, T. Imato
  • Organizer: Pittcon 2009
  • Place of Presentation: Chicago, USA
  • Year and Date: 2009-03-09
• [Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device (2009)
  • Author(s): Hizuru Nakajima, et.al.
  • Organizer: PITTCON2009
  • Place of Presentation: アメリカ・シカゴ
  • Year and Date: 2009-03-09
• [Presentation] A surface plasmon resonance sensor on a compact disk-like microfluidic device (2009)
  • Author(s): A.Hemmi, H.Nakajima, A.Moto, T.Usui, T.Tobita, N.Soh, K.Nakano, K.Uchiyama, T.Imato
  • Organizer: The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS2009)
  • Place of Presentation: 韓国済州島
• [Presentation] コンパクトディスク型表面プラズモン共鳴センサの開発 (2008)
  • Author(s): 本明紘, 辺見彰秀, 飛田達也, 中嶋秀, 宗伸明, 中野幸二, 山崎吉一, 諸岡成治, 今任稔彦
  • Organizer: 第18回化学とマイクロ・ナノシステム研究会
  • Place of Presentation: 京都大学
  • Year and Date: 2008-12-09
• [Presentation] コンパクトディスク型表面プラズモン共鳴センサの開発 (2008)
  • Author(s): 中嶋秀, ら
  • Organizer: 第41回日本大学生産工学部学術講演会
  • Place of Presentation: 日本大学
  • Year and Date: 2008-12-06
• [Presentation] コンパクトディスク型表面プラズモン共鳴センサの開発 (2008)
  • Author(s): 本明紘, 辺見彰秀, 飛田達也, 中嶋秀, 宗伸明, 中野幸二, 山崎吉一, 諸岡成治, 今任稔彦
  • Organizer: 日本分析化学会第57年会
  • Place of Presentation: 福岡大学
  • Year and Date: 2008-09-10
• [Presentation] Surface Plasmon Resonance Sensor with Multi Detection Points and Its Application to Simultaneous Immunoassay for IgA and IgG (2008)
  • Author(s): Akihide Hemmi, et.al.
  • Organizer: 12th International Meeting on Chemical Sensors
  • Place of Presentation: アメリカ・コロンバス
  • Year and Date: 2008-07-16
• [Presentation] コンパクトディスク型マイクロチップを用いるポンプレス流れ分析法に関する基礎的検討 (2008)
  • Author(s): 本明紘, 辺見彰秀, 飛田達也, 中嶋秀, 宗伸明, 中野幸二, 山崎吉一, 諸岡成治, 今任稔彦
  • Organizer: 日本分析化学会第69回分析化学討論会
  • Place of Presentation: 名古屋国際会議場
  • Year and Date: 2008-05-15
• [Remarks] ホームページ等
  • URL: http://www.comp.tmu.ac.jp/uchiyama/
• [Remarks]
  • URL: http://www.comp.tmu.ac.jp/uchiyama/
• [Remarks]
  • URL: http://www.comp.tmu.ac.jp/uchiyama/