Functions of multi-functional transcription factors in recombination activation
| Project/Area Number |
20770001
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | The University of Tokyo |
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Principal Investigator |
YAMADA Takatomi The University of Tokyo, 大学院・総合文化研究科, 助教 (30451850)
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| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 減数分裂 / 相同組換え / 多機能性転写因子 / ATF / CREB |
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| Research Abstract |
We are interested in mechanisms of homologous recombination in chromatin structure. In this study, we focused on a multi-functional transcription factor Atf1, and examined its molecular features in recombination activation. Our study revealed that Atf1 and its surrounding histones have unique posttranslational modification patterns, and such patterns are in close relationship to recombination activity.
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Report
(3 results)
Research Products
(12 results)
