Research Project
Grant-in-Aid for Young Scientists (B)
The mitochondrially-localized superoxide dismutase (SOD) is vital for oxidative stress response. SOD seem to be acetylated at lysine residues. I have studied functional significance and molecular mechanism of the SOD acetylation. I found that two metabolic genes were important for the acetylation of SOD in fission yeast. Reduction in acetylation made SOD slightly more active, but the mutation of the defined acetylated residues did not affect the activity.
All 2009 2008
All Presentation (3 results)
