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Sensory organ developments and responses corresponding to exogenous stimuli in fish.

Research Project

Project/Area Number 20770045
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Morphology/Structure
Research InstitutionKyoto University

Principal Investigator

IIDA Atsuo  Kyoto University, 医学研究科, 研究員(COE) (90437278)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords器官形成 / 側線 / 増殖因子 / 感覚器 / ゼブラフィッシュ / ニューレグリン / 形態形成
Research Abstract

My purpose is a clarification of functions of the neuregulin, known as responsible gene of the schizophrenia, using live animal.
To analyze roles of neuregulin in sensory organ developments and responses corresponding to exogenous stimuli, I chose lateral line, which is a sensory organ in fish, as a model tissue, and zebrafish as a model animal.
In the result, I identify several novel genes as markers of lateral line, but could not trace a detailed behavior of lateral line developments and its responses.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (16 results)

All 2010 2009 2008 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (14 results)

  • [Journal Article] Metalloprotease- Dependent Onset of Blood Circulation In Zebrafish.

    • Author(s)
      Iida, A., et al.
    • Journal Title

      Current Biology. (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Metalloprotease-Dependent Onset of Blood Circulation In Zebrafish

    • Author(s)
      Atsuo Iida, et al.
    • Journal Title

      Current Biology (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Intravascular Proteolysis Triggers Synchronous Start of Blood Circulation in Zebrafish.2010

    • Author(s)
      Atsuo Iida
    • Organizer
      CDBシンポジウム2010「Frontiers in Organogenesis」
    • Place of Presentation
      兵庫県
    • Year and Date
      2010-03-23
    • Related Report
      2009 Final Research Report
  • [Presentation] Intravascular Proteolysis Triggers Synchronous Start of Blood Circulation in Zebrafish2010

    • Author(s)
      Atsuo Iida
    • Organizer
      CDBシンポジウム2010「Frontiers in Organogenesis」
    • Place of Presentation
      兵庫県
    • Year and Date
      2010-03-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] A Novel Role of ADAM Protease in Development.2010

    • Author(s)
      Atsuo Iida, et al.
    • Organizer
      North American Vascular Biology Organization, Developmental Vascular Biology Workshop
    • Place of Presentation
      アメリカ
    • Year and Date
      2010-02-10
    • Related Report
      2009 Final Research Report
  • [Presentation] A Novel Role of ADAM Protease in Development2010

    • Author(s)
      Atsuo Iida, et al.
    • Organizer
      North American Vascular Biology Organization, Developmental Vascular Biology Workshop
    • Place of Presentation
      モントレー(アメリカ)
    • Year and Date
      2010-02-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Intravascular Proteolysis Triggers Synchronous Start of Blood Circulation in Zebrafish2009

    • Author(s)
      飯田敦夫、坂口和弥、佐藤洋旭、岩木彩、瀬原淳子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      神奈川県
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 胚発生における最初の血液循環は、血管内腔への赤血球の移動とプロテアーゼによる細胞接着の解除により開始する2009

    • Author(s)
      飯田敦夫、坂口和弥、佐藤洋旭、岩木彩、瀬原淳子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      神奈川県
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] ADAM8 is an Active Metalloprotease That Can Shed the Ectodomain of PSGL-12009

    • Author(s)
      佐藤洋旭、飯田敦夫、瀬原淳子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      神奈川県
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 膜型プロテアーゼADAMにより制御される血液循環の開始はプロテアーゼ阻害剤の血管内投与により抑制できる2009

    • Author(s)
      岩木彩、飯田敦夫、瀬原淳子
    • Organizer
      第15回小型魚類研究会
    • Place of Presentation
      愛知県
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 胚発生における最初の血液循環は、血管内腔への赤血球の移動とプロテアーゼによる細胞接着の解除により開始する2009

    • Author(s)
      飯田敦夫、坂口和弥、佐藤洋旭、岩木彩、瀬原淳子
    • Organizer
      第15回小型魚類研究会
    • Place of Presentation
      愛知県
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] Roles of ADAM protease Meltrinβ(ADAM19) in the circuatory organ development.2009

    • Author(s)
      Atsuo Iida, et al.
    • Organizer
      International Society for Stem Cell Research 7th Annual Meeting
    • Place of Presentation
      スペイン
    • Year and Date
      2009-07-09
    • Related Report
      2009 Final Research Report
  • [Presentation] Roles of ADAM protease Meltrin β (ADAM19) in the circuatory organ development.2009

    • Author(s)
      Atsuo Iida, et al.
    • Organizer
      International Society for Stem Cell Research 7th Annual Meeting
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2009-07-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] ゼブラフィッシュの筋維持におけるErbBリガンド・ニューレグリンの役割2009

    • Author(s)
      瀬原淳子、佐藤文規、飯田敦夫、佐藤智美
    • Organizer
      第25回宇宙利用シンポジウム
    • Place of Presentation
      神奈川県
    • Year and Date
      2009-01-25
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] ゼブラフィッシュの形態形成におけるadam-8プロテアーゼ因子の役割2008

    • Author(s)
      飯田敦夫、坂口和弥、工藤寛明、坂口泰子、川原敦雄、瀬原淳子
    • Organizer
      BMB2008
    • Place of Presentation
      兵庫県
    • Year and Date
      2008-12-09
    • Related Report
      2009 Final Research Report
  • [Presentation] ゼブラフィッシュの形態形成におけるadam-8プロテアーゼ因子の役割2008

    • Author(s)
      飯田敦夫、坂口和弥、工藤寛明、坂口泰子、川原敦雄、瀬原淳子
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会)
    • Place of Presentation
      兵庫県
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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