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Study on autonomic functions of a hypothalamic neuropeptide, GnIH, in the quail

Research Project

Project/Area Number 20770056
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Animal physiology/Animal behavior
Research InstitutionHiroshima University

Principal Investigator

UKENA Kazuyohsi  Hiroshima University, 大学院・総合科学研究科, 准教授 (10304370)

Project Period (FY) 2008 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords神経ペプチド / 自律神経調節 / 鳥類 / 生理作用 / 視床下部ホルモン
Research Abstract

Gonadotropin-inhibitory hormone (GnIH) is a novel avian hypothalamic neuropeptide which plays important roles in the hypothalamo-pituitary gonadal axis. The previous study showed that the most prominent GnIH-immunoreactive fibers were seen in the median eminence of the hypothalamus and in the dorsal motor nucleus of the vagus (DMV) in the medulla oblongata, showing GnIH might participate not only in neuroendocrine functions but also in autonomic functions. In this study, we investigated the neural connections between the paraventricular nucleus in the hypothalamus and the DMV. In addition, the receptor for GnIH was localized in the DMV sending efferent fibers into the visceral tissues.

Report

(3 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • Research Products

    (7 results)

All 2010 2009 2008

All Journal Article (7 results) (of which Peer Reviewed: 7 results)

  • [Journal Article] Identification, localization, and function of a novel avian hypothalamic neuropeptide, 26RFa, and its cognate receptor, G protein-coupled receptor-103.2010

    • Author(s)
      Ukena K, et al.
    • Journal Title

      Endocrinology 151(印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH) in birds: discovery, progress and prospect2009

    • Author(s)
      Tsutsui K, Saigoh E, Yin H, Ubuka T, Chowdhury VS, Osugi T, Ukena K, Sharp PJ, Wingfield JC, Bentley GE
    • Journal Title

      J. Neuroendocrinol 21

      Pages: 271-275

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH) in birds : discovery, progress and prospect.2009

    • Author(s)
      Tsutsui K, et al.
    • Journal Title

      J.Neuroendocrinol. 21

      Pages: 271-275

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The orexigenic effect of GnIH is mediated by central opioid receptors in chicks2008

    • Author(s)
      Tachibana T, Masuda N, Tsutsui K, Ukena K, Ueda H
    • Journal Title

      Comp. Biochem. Physiol. A 150

      Pages: 21-25

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Unique form and osmoregulatory function of a neurohypophysial hormone in a urochordate2008

    • Author(s)
      Ukena K.
    • Journal Title

      Endocrinology 149

      Pages: 5254-5261

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum : A new insight into the biosynthesis, metabolism and multiple actions of progesterone a2008

    • Author(s)
      Sakamoto H.
    • Journal Title

      Cerebellum 7

      Pages: 18-25

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The orexigenic effect of GnIH is mediated by central opioid receptors in chicks2008

    • Author(s)
      Tachibana T.
    • Journal Title

      Comp. Biochem. Physiol. A 150

      Pages: 21-25

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed

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Published: 2008-04-01   Modified: 2016-04-21  

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