Structure and function of small RNA-protein complexes
| Project/Area Number |
20770079
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Structural biochemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NISHIMASU Hiroshi The University of Tokyo, 大学院・理学系研究科, 特任助教 (00467044)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | タンパク質 / 核酸 / 結晶構造 |
|---|
| Research Abstract |
We solved the crystal structure of Thermus thermophilus TrmFO, providing a structural basis for the folate/FAD-dependent methylation of tRNA U54. We also solved the crystal structure of Pyrocuccus horikoshii and Methanococcus jannaschii TYW2s, providing a structural basis for the S-adenosylmethionine-dependent transfer of the α-amino-α-carboxypropyl group into tRNA imG-14.
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Report
(4 results)
Research Products
(16 results)
