Research Project
Grant-in-Aid for Young Scientists (B)
Chondroitin proteoglycans are involved in cell division. We analysed chondroitin proteoglycans and related molecules using model organism C. elegans and found following. 1) Two chondroitin proteoglycans are required for proper assembly of the C. elegans eggshell and osmotic barriear. 2) Chondroitin plays an important role on meiosis in nematode germ line. 3) Chondroitin proteoglycans are imvolved in receptor-mediated transport of vitellogenin during oogenesis. These findings suggest that chondroitin and related molecules are involved in cell division control and molecular transport systems.
All 2010 2009 2008 Other
All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (3 results) Book (2 results) Remarks (3 results) Patent(Industrial Property Rights) (4 results)
FASEB Journal 23
Pages: 2215-2225
Trends in Glycoscience and Glycotechnology 21
Pages: 179-191
10026976648
The FASEB Journal (Published onli ne March 6)
http://srv02.medic.kumamoto-u.ac.jp/dept/tumor/index.html
http://seibutsu.biology.kyushu-u.ac.jp/nomura/index.html